| 1 | Sun 20 Sep 2020 | 52-0 v Real ValladolidReal Betis 2-0 Real Valladolid | Spanish La Liga |
| 2 | Sat 26 Sep 2020 | 5 2-3 v Real MadridReal Betis 2-3 Real Madrid | Spanish La Liga |
| 3 | Tue 29 Sep 2020 | 50-3 v GetafeGetafe 3-0 Real Betis | Spanish La Liga |
| 4 | Sat 3 Oct 2020 | 5 2-0 v ValenciaValencia 0-2 Real Betis | Spanish La Liga |
| 5 | Sun 18 Oct 2020 | 5 0-3 v Real SociedadReal Betis 0-3 Real Sociedad | Spanish La Liga |
| 6 | Sat 24 Oct 2020 | 50-2 v Atlético MadridAtlético Madrid 2-0 Real Betis | Spanish La Liga |
| 7 | Sun 1 Nov 2020 | 53-1 v ElcheReal Betis 3-1 Elche | Spanish La Liga |
| 8 | Sat 7 Nov 2020 | 52-5 v BarcelonaBarcelona 5-2 Real Betis | Spanish La Liga |
| 9 | Mon 30 Nov 2020 | 50-2 v EibarReal Betis 0-2 Eibar | Spanish La Liga |
| 10 | Sun 6 Dec 2020 | 52-0 v OsasunaOsasuna 0-2 Real Betis | Spanish La Liga |
| 11 | Sun 13 Dec 2020 | 51-1 v VillarrealReal Betis 1-1 Villarreal | Spanish La Liga |
| 12 | Sun 20 Dec 2020 | 50-2 v GranadaGranada 2-0 Real Betis | Spanish La Liga |
| 13 | Sun 11 Apr 2021 | 51-1 v Atlético MadridReal Betis 1-1 Atlético Madrid | Spanish La Liga |
| 14 | Wed 21 Apr 2021 | 50-0 v Athletic BilbaoReal Betis 0-0 Athletic Bilbao | Spanish La Liga |
| 15 | Mon 10 May 2021 | 52-1 v GranadaReal Betis 2-1 Granada | Spanish La Liga |
| 16 | Thu 13 May 2021 | 51-1 v EibarEibar 1-1 Real Betis | Spanish La Liga |
| 17 | Sun 16 May 2021 | 51-0 v HuescaReal Betis 1-0 Huesca | Spanish La Liga |
| 18 | Sat 22 May 2021 | 53-2 v Celta VigoCelta Vigo 2-3 Real Betis | Spanish La Liga |
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