| 1 | Sun 25 Oct 2020 | 180-2 v AlavésReal Valladolid 0-2 Alavés | Spanish La Liga |
| 2 | Sun 22 Nov 2020 | 18 3-1 v GranadaGranada 1-3 Real Valladolid | Spanish La Liga |
| 3 | Fri 27 Nov 2020 | 181-1 v LevanteReal Valladolid 1-1 Levante | Spanish La Liga |
| 4 | Sat 5 Dec 2020 | 180-2 v Atlético MadridAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 5 | Fri 11 Dec 2020 | 183-2 v OsasunaReal Valladolid 3-2 Osasuna | Spanish La Liga |
| 6 | Sat 20 Feb 2021 | 180-1 v Real MadridReal Valladolid 0-1 Real Madrid | Spanish La Liga |
| 7 | Sun 28 Feb 2021 | 181-1 v Celta VigoCelta Vigo 1-1 Real Valladolid | Spanish La Liga |
| 8 | Sat 6 Mar 2021 | 182-1 v GetafeReal Valladolid 2-1 Getafe | Spanish La Liga |
| 9 | Sat 13 Mar 2021 | 180-0 v OsasunaOsasuna 0-0 Real Valladolid | Spanish La Liga |
| 10 | Sat 20 Mar 2021 | 181-1 v SevillaReal Valladolid 1-1 Sevilla | Spanish La Liga |
| 11 | Mon 5 Apr 2021 | 180-1 v BarcelonaBarcelona 1-0 Real Valladolid | Spanish La Liga |
| 12 | Sun 11 Apr 2021 | 18 1-2 v GranadaReal Valladolid 1-2 Granada | Spanish La Liga |
| 13 | Wed 21 Apr 2021 | 18 1-1 v ElcheElche 1-1 Real Valladolid | Spanish La Liga |
| 14 | Wed 28 Apr 2021 | 182-2 v Athletic BilbaoAthletic Bilbao 2-2 Real Valladolid | Spanish La Liga |
| 15 | Sun 2 May 2021 | 18 1-1 v Real BetisReal Valladolid 1-1 Real Betis | Spanish La Liga |
| 16 | Sun 9 May 2021 | 180-3 v ValenciaValencia 3-0 Real Valladolid | Spanish La Liga |
| 17 | Thu 13 May 2021 | 180-2 v VillarrealReal Valladolid 0-2 Villarreal | Spanish La Liga |
| 18 | Sat 22 May 2021 | 181-2 v Atlético MadridReal Valladolid 1-2 Atlético Madrid | Spanish La Liga |
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