| 1 | Sun 27 Sep 2020 | 81-1 v Celta VigoReal Valladolid 1-1 Celta Vigo | Spanish La Liga |
| 2 | Wed 30 Sep 2020 | 80-1 v Real MadridReal Madrid 1-0 Real Valladolid | Spanish La Liga |
| 3 | Sat 3 Oct 2020 | 81-2 v EibarReal Valladolid 1-2 Eibar | Spanish La Liga |
| 4 | Sun 18 Oct 2020 | 82-2 v HuescaHuesca 2-2 Real Valladolid | Spanish La Liga |
| 5 | Sun 25 Oct 2020 | 80-2 v AlavésReal Valladolid 0-2 Alavés | Spanish La Liga |
| 6 | Mon 2 Nov 2020 | 80-2 v VillarrealVillarreal 2-0 Real Valladolid | Spanish La Liga |
| 7 | Sat 5 Dec 2020 | 80-2 v Atlético MadridAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 8 | Fri 11 Dec 2020 | 8 3-2 v OsasunaReal Valladolid 3-2 Osasuna | Spanish La Liga |
| 9 | Tue 22 Dec 2020 | 80-3 v BarcelonaReal Valladolid 0-3 Barcelona | Spanish La Liga |
| 10 | Tue 29 Dec 2020 | 80-0 v CádizCádiz 0-0 Real Valladolid | Spanish La Liga |
| 11 | Sat 2 Jan 2021 | 81-0 v GetafeGetafe 0-1 Real Valladolid | Spanish La Liga |
| 12 | Sun 10 Jan 2021 | 80-1 v ValenciaReal Valladolid 0-1 Valencia | Spanish La Liga |
| 13 | Tue 19 Jan 2021 | 82-2 v ElcheReal Valladolid 2-2 Elche | Spanish La Liga |
| 14 | Fri 22 Jan 2021 | 82-2 v LevanteLevante 2-2 Real Valladolid | Spanish La Liga |
| 15 | Fri 29 Jan 2021 | 81-3 v HuescaReal Valladolid 1-3 Huesca | Spanish La Liga |
| 16 | Fri 5 Feb 2021 | 80-1 v AlavésAlavés 1-0 Real Valladolid | Spanish La Liga |
| 17 | Sat 13 Feb 2021 | 8 1-1 v EibarEibar 1-1 Real Valladolid | Spanish La Liga |
| 18 | Sat 20 Feb 2021 | 80-1 v Real MadridReal Valladolid 0-1 Real Madrid | Spanish La Liga |
| 19 | Sat 20 Mar 2021 | 81-1 v SevillaReal Valladolid 1-1 Sevilla | Spanish La Liga |
| 20 | Sun 2 May 2021 | 81-1 v Real BetisReal Valladolid 1-1 Real Betis | Spanish La Liga |
| 21 | Sun 9 May 2021 | 80-3 v ValenciaValencia 3-0 Real Valladolid | Spanish La Liga |
| 22 | Sun 16 May 2021 | 8 1-4 v Real SociedadReal Sociedad 4-1 Real Valladolid | Spanish La Liga |
| 23 | Sat 22 May 2021 | 81-2 v Atlético MadridReal Valladolid 1-2 Atlético Madrid | Spanish La Liga |
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