| 1 | Sun 20 Sep 2020 | 60-2 v Real BetisReal Betis 2-0 Real Valladolid | Spanish La Liga |
| 2 | Sun 27 Sep 2020 | 6 1-1 v Celta VigoReal Valladolid 1-1 Celta Vigo | Spanish La Liga |
| 3 | Wed 30 Sep 2020 | 6 0-1 v Real MadridReal Madrid 1-0 Real Valladolid | Spanish La Liga |
| 4 | Sun 18 Oct 2020 | 6 2-2 v HuescaHuesca 2-2 Real Valladolid | Spanish La Liga |
| 5 | Mon 2 Nov 2020 | 60-2 v VillarrealVillarreal 2-0 Real Valladolid | Spanish La Liga |
| 6 | Sun 8 Nov 2020 | 62-1 v Athletic BilbaoReal Valladolid 2-1 Athletic Bilbao | Spanish La Liga |
| 7 | Sun 22 Nov 2020 | 63-1 v GranadaGranada 1-3 Real Valladolid | Spanish La Liga |
| 8 | Fri 27 Nov 2020 | 61-1 v LevanteReal Valladolid 1-1 Levante | Spanish La Liga |
| 9 | Sat 5 Dec 2020 | 60-2 v Atlético MadridAtlético Madrid 2-0 Real Valladolid | Spanish La Liga |
| 10 | Fri 11 Dec 2020 | 63-2 v OsasunaReal Valladolid 3-2 Osasuna | Spanish La Liga |
| 11 | Sat 19 Dec 2020 | 6 1-1 v SevillaSevilla 1-1 Real Valladolid | Spanish La Liga |
| 12 | Tue 29 Dec 2020 | 60-0 v CádizCádiz 0-0 Real Valladolid | Spanish La Liga |
| 13 | Sat 2 Jan 2021 | 61-0 v GetafeGetafe 0-1 Real Valladolid | Spanish La Liga |
| 14 | Sun 10 Jan 2021 | 6 0-1 v ValenciaReal Valladolid 0-1 Valencia | Spanish La Liga |
| 15 | Fri 22 Jan 2021 | 62-2 v LevanteLevante 2-2 Real Valladolid | Spanish La Liga |
| 16 | Fri 29 Jan 2021 | 61-3 v HuescaReal Valladolid 1-3 Huesca | Spanish La Liga |
| 17 | Fri 5 Feb 2021 | 6 0-1 v AlavésAlavés 1-0 Real Valladolid | Spanish La Liga |
| 18 | Sat 13 Feb 2021 | 61-1 v EibarEibar 1-1 Real Valladolid | Spanish La Liga |
| 19 | Sat 20 Feb 2021 | 60-1 v Real MadridReal Valladolid 0-1 Real Madrid | Spanish La Liga |
| 20 | Sun 28 Feb 2021 | 61-1 v Celta VigoCelta Vigo 1-1 Real Valladolid | Spanish La Liga |
| 21 | Sat 13 Mar 2021 | 60-0 v OsasunaOsasuna 0-0 Real Valladolid | Spanish La Liga |
| 22 | Sat 20 Mar 2021 | 61-1 v SevillaReal Valladolid 1-1 Sevilla | Spanish La Liga |
| 23 | Mon 5 Apr 2021 | 6 0-1 v BarcelonaBarcelona 1-0 Real Valladolid | Spanish La Liga |
| 24 | Sun 11 Apr 2021 | 6 1-2 v GranadaReal Valladolid 1-2 Granada | Spanish La Liga |
| 25 | Wed 21 Apr 2021 | 61-1 v ElcheElche 1-1 Real Valladolid | Spanish La Liga |
| 26 | Thu 13 May 2021 | 60-2 v VillarrealReal Valladolid 0-2 Villarreal | Spanish La Liga |
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