| 1 | Sat 31 Jul 2021 | 70-0 v Sporting de CharleroiSporting de Charleroi 0-0 Sint-Truidense VV | Belgian First Division A |
| 2 | Sat 7 Aug 2021 | 71-3 v SV Zulte WaregemSint-Truidense VV 1-3 SV Zulte Waregem | Belgian First Division A |
| 3 | Sat 14 Aug 2021 | 71-2 v KAS EupenKAS Eupen 2-1 Sint-Truidense VV | Belgian First Division A |
| 4 | Sat 21 Aug 2021 | 70-2 v KV KortrijkSint-Truidense VV 0-2 KV Kortrijk | Belgian First Division A |
| 5 | Sat 28 Aug 2021 | 71-0 v Cercle BruggeCercle Brugge 0-1 Sint-Truidense VV | Belgian First Division A |
| 6 | Thu 16 Sep 2021 | 71-0 v FC Flora TallinnFC Flora Tallinn 0-1 KAA Gent | UEFA Europa Conference League |
| 7 | Sun 19 Sep 2021 | 70-1 v KV KortrijkKV Kortrijk 1-0 KAA Gent | Belgian First Division A |
| 8 | Thu 23 Sep 2021 | 71-1 v RSC AnderlechtRSC Anderlecht 1-1 KAA Gent | Belgian First Division A |
| 9 | Sun 26 Sep 2021 | 72-1 v Cercle BruggeKAA Gent 2-1 Cercle Brugge | Belgian First Division A |
| 10 | Sun 17 Oct 2021 | 72-0 v KAS EupenKAA Gent 2-0 KAS Eupen | Belgian First Division A |
| 11 | Thu 21 Oct 2021 | 71-0 v FK PartizanFK Partizan 0-1 KAA Gent | UEFA Europa Conference League |
| 12 | Sun 24 Oct 2021 | 7 3-0 v KRC GenkKRC Genk 0-3 KAA Gent | Belgian First Division A |
| 13 | Thu 25 Nov 2021 | 70-1 v Anorthosis FamagustaAnorthosis Famagusta 1-0 KAA Gent | UEFA Europa Conference League |
| 14 | Sun 28 Nov 2021 | 73-1 v Standard LiègeKAA Gent 3-1 Standard Liège | Belgian First Division A |
| 15 | Thu 9 Dec 2021 | 71-0 v FC Flora TallinnKAA Gent 1-0 FC Flora Tallinn | UEFA Europa Conference League |
| 16 | Fri 14 Jan 2022 | 72-2 v KV KortrijkKAA Gent 2-2 KV Kortrijk | Belgian First Division A |
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