| 1 | Sat 14 Aug 2021 | 231-0 v VfL BochumVfL Wolfsburg 1-0 VfL Bochum | German Bundesliga |
| 2 | Sat 21 Aug 2021 | 232-1 v Hertha BerlinHertha Berlin 1-2 VfL Wolfsburg | German Bundesliga |
| 3 | Sun 29 Aug 2021 | 23 1-0 v RB LeipzigVfL Wolfsburg 1-0 RB Leipzig | German Bundesliga |
| 4 | Sat 11 Sep 2021 | 232-0 v Greuther FürthGreuther Fürth 0-2 VfL Wolfsburg | German Bundesliga |
| 5 | Tue 14 Sep 2021 | 23 0-0 v LilleLille 0-0 VfL Wolfsburg | UEFA Champions League Group G |
| 6 | Sun 19 Sep 2021 | 23 1-1 v Eintracht FrankfurtVfL Wolfsburg 1-1 Eintracht Frankfurt | German Bundesliga |
| 7 | Sat 25 Sep 2021 | 231-3 v 1899 Hoffenheim1899 Hoffenheim 3-1 VfL Wolfsburg | German Bundesliga |
| 8 | Wed 29 Sep 2021 | 23 1-1 v SevillaVfL Wolfsburg 1-1 Sevilla | UEFA Champions League Group G |
| 9 | Sat 2 Oct 2021 | 231-3 v Borussia MönchengladbachVfL Wolfsburg 1-3 Borussia Mönchengladbach | German Bundesliga |
| 10 | Sat 16 Oct 2021 | 230-2 v 1. FC Union Berlin1. FC Union Berlin 2-0 VfL Wolfsburg | German Bundesliga |
| 11 | Sat 23 Oct 2021 | 23 0-2 v SC FreiburgVfL Wolfsburg 0-2 SC Freiburg | German Bundesliga |
| 12 | Sat 30 Oct 2021 | 232-0 v Bayer 04 LeverkusenBayer 04 Leverkusen 0-2 VfL Wolfsburg | German Bundesliga |
| 13 | Tue 2 Nov 2021 | 232-1 v SV Red Bull SalzburgVfL Wolfsburg 2-1 SV Red Bull Salzburg | UEFA Champions League Group G |
| 14 | Sat 6 Nov 2021 | 23 1-0 v FC AugsburgVfL Wolfsburg 1-0 FC Augsburg | German Bundesliga |
| 15 | Tue 23 Nov 2021 | 23 0-2 v SevillaSevilla 2-0 VfL Wolfsburg | UEFA Champions League Group G |
| 16 | Sat 27 Nov 2021 | 231-3 v Borussia DortmundVfL Wolfsburg 1-3 Borussia Dortmund | German Bundesliga |
| 17 | Sat 4 Dec 2021 | 230-3 v Mainz 05Mainz 05 3-0 VfL Wolfsburg | German Bundesliga |
| 18 | Wed 8 Dec 2021 | 231-3 v LilleVfL Wolfsburg 1-3 Lille | UEFA Champions League Group G |
| 19 | Sat 11 Dec 2021 | 230-2 v VfB StuttgartVfL Wolfsburg 0-2 VfB Stuttgart | German Bundesliga |
| 20 | Fri 17 Dec 2021 | 230-4 v Bayern MunichBayern Munich 4-0 VfL Wolfsburg | German Bundesliga |
| 21 | Sun 6 Feb 2022 | 230-5 v ReimsReims 5-0 Bordeaux | French Ligue 1 |
| 22 | Sun 13 Feb 2022 | 23 2-3 v LensLens 3-2 Bordeaux | French Ligue 1 |
| 23 | Sun 20 Feb 2022 | 23 1-1 v MonacoBordeaux 1-1 Monaco | French Ligue 1 |
| 24 | Sun 27 Feb 2022 | 231-1 v ClermontClermont 1-1 Bordeaux | French Ligue 1 |
| 25 | Sun 13 Mar 2022 | 23 0-3 v Paris St GermainParis St Germain 3-0 Bordeaux | French Ligue 1 |
| 26 | Sun 20 Mar 2022 | 230-2 v MontpellierBordeaux 0-2 Montpellier | French Ligue 1 |
| 27 | Sun 10 Apr 2022 | 233-1 v MetzBordeaux 3-1 Metz | French Ligue 1 |
| 28 | Sun 17 Apr 2022 | 231-6 v LyonLyon 6-1 Bordeaux | French Ligue 1 |
| 29 | Wed 20 Apr 2022 | 232-2 v Saint ÉtienneBordeaux 2-2 Saint Étienne | French Ligue 1 |
| 30 | Sun 24 Apr 2022 | 233-5 v NantesNantes 5-3 Bordeaux | French Ligue 1 |
| 31 | Sun 1 May 2022 | 230-1 v NiceBordeaux 0-1 Nice | French Ligue 1 |
| 32 | Sun 8 May 2022 | 23 1-4 v AngersAngers 4-1 Bordeaux | French Ligue 1 |
| 33 | Sat 14 May 2022 | 230-0 v LorientBordeaux 0-0 Lorient | French Ligue 1 |
| 34 | Sat 21 May 2022 | 234-2 v BrestBrest 2-4 Bordeaux | French Ligue 1 |
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