| 1 | Sun 22 Aug 2021 | 261-1 v AjaxFC Twente 1-1 Ajax | Dutch Eredivisie |
| 2 | Sun 19 Sep 2021 | 264-1 v VitesseVitesse 1-4 FC Twente | Dutch Eredivisie |
| 3 | Fri 1 Oct 2021 | 261-1 v FC GroningenFC Groningen 1-1 FC Twente | Dutch Eredivisie |
| 4 | Sun 17 Oct 2021 | 261-1 v Willem IIFC Twente 1-1 Willem II | Dutch Eredivisie |
| 5 | Sun 24 Oct 2021 | 261-2 v NEC NijmegenFC Twente 1-2 NEC Nijmegen | Dutch Eredivisie |
| 6 | Sat 30 Oct 2021 | 262-5 v PSV EindhovenPSV Eindhoven 5-2 FC Twente | Dutch Eredivisie |
| 7 | Sat 20 Nov 2021 | 261-0 v Sparta RotterdamSparta Rotterdam 0-1 FC Twente | Dutch Eredivisie |
| 8 | Sun 12 Dec 2021 | 262-1 v RKC WaalwijkFC Twente 2-1 RKC Waalwijk | Dutch Eredivisie |
| 9 | Sat 18 Dec 2021 | 263-1 v PEC ZwollePEC Zwolle 1-3 FC Twente | Dutch Eredivisie |
| 10 | Sat 15 Jan 2022 | 262-0 v sc HeerenveenFC Twente 2-0 sc Heerenveen | Dutch Eredivisie |
| 11 | Sat 5 Feb 2022 | 263-0 v VitesseFC Twente 3-0 Vitesse | Dutch Eredivisie |
| 12 | Sun 13 Feb 2022 | 260-5 v AjaxAjax 5-0 FC Twente | Dutch Eredivisie |
| 13 | Sat 9 Apr 2022 | 262-0 v NEC NijmegenNEC Nijmegen 0-2 FC Twente | Dutch Eredivisie |
| 14 | Fri 22 Apr 2022 | 262-0 v Sparta RotterdamFC Twente 2-0 Sparta Rotterdam | Dutch Eredivisie |
| 15 | Sat 30 Apr 2022 | 261-1 v Heracles AlmeloHeracles Almelo 1-1 FC Twente | Dutch Eredivisie |
| 16 | Wed 11 May 2022 | 263-0 v FC GroningenFC Twente 3-0 FC Groningen | Dutch Eredivisie |
| 17 | Sun 15 May 2022 | 262-1 v FeyenoordFeyenoord 1-2 FC Twente | Dutch Eredivisie |
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