| 1 | Tue 7 Sep 2021 | 240-1 v GillinghamColchester United 0-1 Gillingham | Papa John’s Trophy |
| 2 | Tue 9 Nov 2021 | 240-0 v Ipswich TownIpswich Town 0-0 Colchester United | Papa John’s Trophy |
| 3 | Sat 20 Nov 2021 | 240-1 v StevenageStevenage 1-0 Colchester United | Sky Bet League Two |
| 4 | Tue 23 Nov 2021 | 243-1 v Exeter CityColchester United 3-1 Exeter City | Sky Bet League Two |
| 5 | Fri 26 Nov 2021 | 241-1 v Newport CountyColchester United 1-1 Newport County | Sky Bet League Two |
| 6 | Sun 5 Dec 2021 | 241-2 v Wigan AthleticColchester United 1-2 Wigan Athletic | Emirates FA Cup Second Round |
| 7 | Wed 8 Dec 2021 | 240-0 v Bradford CityBradford City 0-0 Colchester United | Sky Bet League Two |
| 8 | Sat 11 Dec 2021 | 240-3 v WalsallWalsall 3-0 Colchester United | Sky Bet League Two |
| 9 | Sat 1 Jan 2022 | 241-3 v Crawley TownCrawley Town 3-1 Colchester United | Sky Bet League Two |
| 10 | Tue 4 Jan 2022 | 241-2 v Sutton UnitedSutton United 2-1 Colchester United | Papa John’s Trophy Third Round |
| 11 | Tue 11 Jan 2022 | 240-2 v Forest Green RoversForest Green Rovers 2-0 Colchester United | Sky Bet League Two |
| 12 | Sat 15 Jan 2022 | 240-2 v BarrowColchester United 0-2 Barrow | Sky Bet League Two |
| 13 | Tue 18 Jan 2022 | 242-3 v Sutton UnitedSutton United 3-2 Colchester United | Sky Bet League Two |
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