| 1 | Thu 16 Sep 2021 | 282-2 v RennesRennes 2-2 Tottenham Hotspur | UEFA Europa Conference League |
| 2 | Sun 19 Sep 2021 | 280-3 v ChelseaTottenham Hotspur 0-3 Chelsea | Premier League |
| 3 | Wed 22 Sep 2021 | 28 2-2 v Wolverhampton WanderersWolverhampton Wanderers 2-2 Tottenham Hotspur | Carabao Cup Third Round |
| 4 | Sun 26 Sep 2021 | 281-3 v ArsenalArsenal 3-1 Tottenham Hotspur | Premier League |
| 5 | Sun 3 Oct 2021 | 282-1 v Aston VillaTottenham Hotspur 2-1 Aston Villa | Premier League |
| 6 | Sun 17 Oct 2021 | 283-2 v Newcastle UnitedNewcastle United 2-3 Tottenham Hotspur | Premier League |
| 7 | Sun 24 Oct 2021 | 280-1 v West Ham UnitedWest Ham United 1-0 Tottenham Hotspur | Premier League |
| 8 | Wed 27 Oct 2021 | 281-0 v BurnleyBurnley 0-1 Tottenham Hotspur | Carabao Cup Round of 16 |
| 9 | Sat 30 Oct 2021 | 280-3 v Manchester UnitedTottenham Hotspur 0-3 Manchester United | Premier League |
| 10 | Thu 4 Nov 2021 | 283-2 v VitesseTottenham Hotspur 3-2 Vitesse | UEFA Europa Conference League |
| 11 | Sun 7 Nov 2021 | 28 0-0 v EvertonEverton 0-0 Tottenham Hotspur | Premier League |
| 12 | Thu 25 Nov 2021 | 281-2 v Mura Murska SobotaMura Murska Sobota 2-1 Tottenham Hotspur | UEFA Europa Conference League |
| 13 | Sun 19 Dec 2021 | 282-2 v LiverpoolTottenham Hotspur 2-2 Liverpool | Premier League |
| 14 | Sun 26 Dec 2021 | 283-0 v Crystal PalaceTottenham Hotspur 3-0 Crystal Palace | Premier League |
| 15 | Wed 5 Jan 2022 | 280-2 v ChelseaChelsea 2-0 Tottenham Hotspur | Carabao Cup Semi Final |
| 16 | Sun 9 Jan 2022 | 283-1 v MorecambeTottenham Hotspur 3-1 Morecambe | Emirates FA Cup Third Round |
| 17 | Sat 5 Feb 2022 | 280-2 v MonacoMonaco 2-0 Lyon | French Ligue 1 |
| 18 | Sat 12 Feb 2022 | 282-0 v NiceLyon 2-0 Nice | French Ligue 1 |
| 19 | Sat 19 Feb 2022 | 281-1 v LensLens 1-1 Lyon | French Ligue 1 |
| 20 | Sun 27 Feb 2022 | 280-1 v LilleLyon 0-1 Lille | French Ligue 1 |
| 21 | Wed 9 Mar 2022 | 281-0 v FC PortoFC Porto 0-1 Lyon | UEFA Europa League Round of 16 |
| 22 | Sun 13 Mar 2022 | 28 2-4 v RennesLyon 2-4 Rennes | French Ligue 1 |
| 23 | Thu 17 Mar 2022 | 281-1 v FC PortoLyon 1-1 FC Porto | UEFA Europa League Round of 16 |
| 24 | Sun 3 Apr 2022 | 283-2 v AngersLyon 3-2 Angers | French Ligue 1 |
| 25 | Thu 7 Apr 2022 | 281-1 v West Ham UnitedWest Ham United 1-1 Lyon | UEFA Europa League Quarter Final |
| 26 | Sun 10 Apr 2022 | 281-1 v StrasbourgStrasbourg 1-1 Lyon | French Ligue 1 |
| 27 | Thu 14 Apr 2022 | 280-3 v West Ham UnitedLyon 0-3 West Ham United | UEFA Europa League Quarter Final |
| 28 | Sun 1 May 2022 | 283-0 v MarseilleMarseille 0-3 Lyon | French Ligue 1 |
| 29 | Sun 8 May 2022 | 28 2-3 v MetzMetz 3-2 Lyon | French Ligue 1 |
| 30 | Sat 14 May 2022 | 28 3-2 v NantesLyon 3-2 Nantes | French Ligue 1 |
| 31 | Sat 21 May 2022 | 282-1 v ClermontClermont 1-2 Lyon | French Ligue 1 |
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