| 1 | Sun 8 Aug 2021 | 21-1 v LorientSaint Étienne 1-1 Lorient | French Ligue 1 |
| 2 | Sun 15 Aug 2021 | 22-2 v LensLens 2-2 Saint Étienne | French Ligue 1 |
| 3 | Sat 21 Aug 2021 | 21-1 v LilleSaint Étienne 1-1 Lille | French Ligue 1 |
| 4 | Sat 28 Aug 2021 | 21-3 v MarseilleMarseille 3-1 Saint Étienne | French Ligue 1 |
| 5 | Mon 6 Sep 2021 | 41-2 v Côte d'IvoireCôte d'Ivoire 2-1 Cameroon | World Cup Qualification (Africa) Group D |
| 6 | Sun 12 Sep 2021 | 20-2 v MontpellierMontpellier 2-0 Saint Étienne | French Ligue 1 |
| 7 | Sat 18 Sep 2021 | 21-2 v BordeauxSaint Étienne 1-2 Bordeaux | French Ligue 1 |
| 8 | Wed 22 Sep 2021 | 21-3 v MonacoMonaco 3-1 Saint Étienne | French Ligue 1 |
| 9 | Sat 25 Sep 2021 | 20-3 v NiceSaint Étienne 0-3 Nice | French Ligue 1 |
| 10 | Sun 3 Oct 2021 | 21-1 v LyonSaint Étienne 1-1 Lyon | French Ligue 1 |
| 11 | Fri 8 Oct 2021 | 43-1 v MozambiqueCameroon 3-1 Mozambique | World Cup Qualification (Africa) Group D |
| 12 | Mon 11 Oct 2021 | 41-0 v MozambiqueMozambique 0-1 Cameroon | World Cup Qualification (Africa) Group D |
| 13 | Sun 17 Oct 2021 | 2 1-5 v StrasbourgStrasbourg 5-1 Saint Étienne | French Ligue 1 |
| 14 | Fri 22 Oct 2021 | 22-2 v AngersSaint Étienne 2-2 Angers | French Ligue 1 |
| 15 | Sun 28 Nov 2021 | 21-3 v Paris St GermainSaint Étienne 1-3 Paris St Germain | French Ligue 1 |
| 16 | Wed 1 Dec 2021 | 20-1 v BrestBrest 1-0 Saint Étienne | French Ligue 1 |
| 17 | Sun 5 Dec 2021 | 20-5 v RennesSaint Étienne 0-5 Rennes | French Ligue 1 |
| 18 | Mon 17 Jan 2022 | 41-1 v Cape VerdeCape Verde 1-1 Cameroon | Africa Cup of Nations Group A |
| 19 | Thu 3 Feb 2022 | 40-0 v EgyptCameroon 0-0 Egypt | Africa Cup of Nations Semi Final |
| 20 | Sat 5 Feb 2022 | 43-3 v Burkina FasoBurkina Faso 3-3 Cameroon | Africa Cup of Nations |
| 21 | Sat 26 Feb 2022 | 21-3 v Paris St GermainParis St Germain 3-1 Saint Étienne | French Ligue 1 |
| 22 | Fri 11 Mar 2022 | 2 0-0 v LilleLille 0-0 Saint Étienne | French Ligue 1 |
| 23 | Fri 18 Mar 2022 | 21-1 v TroyesSaint Étienne 1-1 Troyes | French Ligue 1 |
| 24 | Sun 3 Apr 2022 | 22-4 v MarseilleSaint Étienne 2-4 Marseille | French Ligue 1 |
| 25 | Fri 8 Apr 2022 | 22-6 v LorientLorient 6-2 Saint Étienne | French Ligue 1 |
| 26 | Wed 20 Apr 2022 | 22-2 v BordeauxBordeaux 2-2 Saint Étienne | French Ligue 1 |
| 27 | Sat 30 Apr 2022 | 20-2 v RennesRennes 2-0 Saint Étienne | French Ligue 1 |
| 28 | Wed 11 May 2022 | 2 2-4 v NiceNice 4-2 Saint Étienne | French Ligue 1 |
| 29 | Sat 14 May 2022 | 21-2 v ReimsSaint Étienne 1-2 Reims | French Ligue 1 |
| 30 | Sat 21 May 2022 | 21-1 v NantesNantes 1-1 Saint Étienne | French Ligue 1 |
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