| 1 | Wed 20 Oct 2021 | 61-3 v SV Red Bull SalzburgSV Red Bull Salzburg 3-1 VfL Wolfsburg | UEFA Champions League Group G |
| 2 | Sat 23 Oct 2021 | 60-2 v SC FreiburgVfL Wolfsburg 0-2 SC Freiburg | German Bundesliga |
| 3 | Sat 30 Oct 2021 | 62-0 v Bayer 04 LeverkusenBayer 04 Leverkusen 0-2 VfL Wolfsburg | German Bundesliga |
| 4 | Tue 2 Nov 2021 | 62-1 v SV Red Bull SalzburgVfL Wolfsburg 2-1 SV Red Bull Salzburg | UEFA Champions League Group G |
| 5 | Sat 6 Nov 2021 | 61-0 v FC AugsburgVfL Wolfsburg 1-0 FC Augsburg | German Bundesliga |
| 6 | Sat 20 Nov 2021 | 62-2 v Arminia BielefeldArminia Bielefeld 2-2 VfL Wolfsburg | German Bundesliga |
| 7 | Tue 23 Nov 2021 | 60-2 v SevillaSevilla 2-0 VfL Wolfsburg | UEFA Champions League Group G |
| 8 | Sat 27 Nov 2021 | 61-3 v Borussia DortmundVfL Wolfsburg 1-3 Borussia Dortmund | German Bundesliga |
| 9 | Sat 4 Dec 2021 | 60-3 v Mainz 05Mainz 05 3-0 VfL Wolfsburg | German Bundesliga |
| 10 | Wed 8 Dec 2021 | 61-3 v LilleVfL Wolfsburg 1-3 Lille | UEFA Champions League Group G |
| 11 | Sat 11 Dec 2021 | 60-2 v VfB StuttgartVfL Wolfsburg 0-2 VfB Stuttgart | German Bundesliga |
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