| 1 | Sat 14 Aug 2021 | 275-2 v Eintracht FrankfurtBorussia Dortmund 5-2 Eintracht Frankfurt | German Bundesliga |
| 2 | Sat 23 Oct 2021 | 273-1 v Arminia BielefeldArminia Bielefeld 1-3 Borussia Dortmund | German Bundesliga |
| 3 | Sat 30 Oct 2021 | 272-0 v 1. FC KölnBorussia Dortmund 2-0 1. FC Köln | German Bundesliga |
| 4 | Wed 3 Nov 2021 | 271-3 v AjaxBorussia Dortmund 1-3 Ajax | UEFA Champions League Group C |
| 5 | Sat 20 Nov 2021 | 272-1 v VfB StuttgartBorussia Dortmund 2-1 VfB Stuttgart | German Bundesliga |
| 6 | Wed 24 Nov 2021 | 271-3 v Sporting LisbonSporting Lisbon 3-1 Borussia Dortmund | UEFA Champions League Group C |
| 7 | Sat 4 Dec 2021 | 272-3 v Bayern MunichBorussia Dortmund 2-3 Bayern Munich | German Bundesliga |
| 8 | Wed 15 Dec 2021 | 273-0 v Greuther FürthBorussia Dortmund 3-0 Greuther Fürth | German Bundesliga |
| 9 | Sat 18 Dec 2021 | 272-3 v Hertha BerlinHertha Berlin 3-2 Borussia Dortmund | German Bundesliga |
| 10 | Sun 6 Feb 2022 | 272-5 v Bayer 04 LeverkusenBorussia Dortmund 2-5 Bayer 04 Leverkusen | German Bundesliga |
| 11 | Sun 13 Feb 2022 | 273-0 v 1. FC Union Berlin1. FC Union Berlin 0-3 Borussia Dortmund | German Bundesliga |
| 12 | Thu 17 Feb 2022 | 272-4 v RangersBorussia Dortmund 2-4 Rangers | UEFA Europa League Round of 32 |
| 13 | Thu 24 Feb 2022 | 272-2 v RangersRangers 2-2 Borussia Dortmund | UEFA Europa League Round of 32 |
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