| 1 | Sat 7 Aug 2021 | 21-2 v Wycombe WanderersWycombe Wanderers 2-1 Accrington Stanley | Sky Bet League One |
| 2 | Sat 14 Aug 2021 | 2 2-1 v Cambridge UnitedAccrington Stanley 2-1 Cambridge United | Sky Bet League One |
| 3 | Tue 17 Aug 2021 | 21-0 v Doncaster RoversAccrington Stanley 1-0 Doncaster Rovers | Sky Bet League One |
| 4 | Sat 21 Aug 2021 | 21-0 v Crewe AlexandraCrewe Alexandra 0-1 Accrington Stanley | Sky Bet League One |
| 5 | Tue 24 Aug 2021 | 20-0 v Oldham AthleticOldham Athletic 0-0 Accrington Stanley | Carabao Cup Second Round |
| 6 | Sat 28 Aug 2021 | 20-2 v Milton Keynes DonsMilton Keynes Dons 2-0 Accrington Stanley | Sky Bet League One |
| 7 | Tue 9 Nov 2021 | 24-1 v Fleetwood TownFleetwood Town 1-4 Accrington Stanley | Papa John’s Trophy |
| 8 | Sat 13 Nov 2021 | 21-4 v Plymouth ArgyleAccrington Stanley 1-4 Plymouth Argyle | Sky Bet League One |
| 9 | Sat 20 Nov 2021 | 22-3 v Sheffield WednesdayAccrington Stanley 2-3 Sheffield Wednesday | Sky Bet League One |
| 10 | Tue 23 Nov 2021 | 20-4 v Burton AlbionBurton Albion 4-0 Accrington Stanley | Sky Bet League One |
| 11 | Sat 27 Nov 2021 | 2 1-0 v Lincoln CityLincoln City 0-1 Accrington Stanley | Sky Bet League One |
| 12 | Sat 4 Dec 2021 | 25-1 v Fleetwood TownAccrington Stanley 5-1 Fleetwood Town | Sky Bet League One |
| 13 | Tue 7 Dec 2021 | 20-2 v AFC WimbledonAccrington Stanley 0-2 AFC Wimbledon | Sky Bet League One |
| 14 | Sat 11 Dec 2021 | 21-0 v Bolton WanderersAccrington Stanley 1-0 Bolton Wanderers | Sky Bet League One |
| 15 | Wed 29 Dec 2021 | 20-0 v Shrewsbury TownShrewsbury Town 0-0 Accrington Stanley | Sky Bet League One |
| 16 | Sat 19 Feb 2022 | 20-2 v Cambridge UnitedCambridge United 2-0 Accrington Stanley | Sky Bet League One |
| 17 | Tue 22 Feb 2022 | 20-2 v Doncaster RoversDoncaster Rovers 2-0 Accrington Stanley | Sky Bet League One |
| 18 | Sat 26 Feb 2022 | 23-2 v Wycombe WanderersAccrington Stanley 3-2 Wycombe Wanderers | Sky Bet League One |
| 19 | Sat 5 Mar 2022 | 20-4 v PortsmouthPortsmouth 4-0 Accrington Stanley | Sky Bet League One |
| 20 | Sat 12 Mar 2022 | 22-1 v Charlton AthleticAccrington Stanley 2-1 Charlton Athletic | Sky Bet League One |
| 21 | Tue 15 Mar 2022 | 21-1 v Sheffield WednesdaySheffield Wednesday 1-1 Accrington Stanley | Sky Bet League One |
| 22 | Sat 19 Mar 2022 | 20-4 v Plymouth ArgylePlymouth Argyle 4-0 Accrington Stanley | Sky Bet League One |
| 23 | Sat 26 Mar 2022 | 21-2 v GillinghamAccrington Stanley 1-2 Gillingham | Sky Bet League One |
| 24 | Sat 9 Apr 2022 | 2 2-1 v Fleetwood TownFleetwood Town 1-2 Accrington Stanley | Sky Bet League One |
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