| 1 | Sat 7 Aug 2021 | 151-1 v Crewe AlexandraCrewe Alexandra 1-1 Cheltenham Town | Sky Bet League One |
| 2 | Tue 10 Aug 2021 | 152-0 v Bristol RoversBristol Rovers 0-2 Cheltenham Town | Carabao Cup First Round |
| 3 | Sat 14 Aug 2021 | 151-3 v Wycombe WanderersCheltenham Town 1-3 Wycombe Wanderers | Sky Bet League One |
| 4 | Tue 17 Aug 2021 | 152-1 v Ipswich TownCheltenham Town 2-1 Ipswich Town | Sky Bet League One |
| 5 | Sat 21 Aug 2021 | 152-3 v Fleetwood TownFleetwood Town 3-2 Cheltenham Town | Sky Bet League One |
| 6 | Tue 24 Aug 2021 | 151-1 v GillinghamGillingham 1-1 Cheltenham Town | Carabao Cup Second Round |
| 7 | Fri 27 Aug 2021 | 151-1 v Burton AlbionBurton Albion 1-1 Cheltenham Town | Sky Bet League One |
| 8 | Sat 4 Sep 2021 | 151-1 v Milton Keynes DonsCheltenham Town 1-1 Milton Keynes Dons | Sky Bet League One |
| 9 | Sat 11 Sep 2021 | 152-1 v Charlton AthleticCharlton Athletic 1-2 Cheltenham Town | Sky Bet League One |
| 10 | Sat 18 Sep 2021 | 151-0 v Oxford UnitedCheltenham Town 1-0 Oxford United | Sky Bet League One |
| 11 | Sat 16 Oct 2021 | 15 1-0 v Accrington StanleyCheltenham Town 1-0 Accrington Stanley | Sky Bet League One |
| 12 | Sat 1 Jan 2022 | 151-1 v Oxford UnitedOxford United 1-1 Cheltenham Town | Sky Bet League One |
| 13 | Sat 8 Jan 2022 | 151-1 v Burton AlbionCheltenham Town 1-1 Burton Albion | Sky Bet League One |
| 14 | Sat 15 Jan 2022 | 151-1 v Charlton AthleticCheltenham Town 1-1 Charlton Athletic | Sky Bet League One |
| 15 | Sat 22 Jan 2022 | 15 0-1 v Rotherham UnitedRotherham United 1-0 Cheltenham Town | Sky Bet League One |
| 16 | Sat 29 Jan 2022 | 150-0 v Wigan AthleticCheltenham Town 0-0 Wigan Athletic | Sky Bet League One |
| 17 | Tue 1 Feb 2022 | 152-2 v AFC WimbledonAFC Wimbledon 2-2 Cheltenham Town | Sky Bet League One |
| 18 | Tue 8 Feb 2022 | 15 2-1 v SunderlandCheltenham Town 2-1 Sunderland | Sky Bet League One |
| 19 | Sat 12 Feb 2022 | 152-0 v Fleetwood TownCheltenham Town 2-0 Fleetwood Town | Sky Bet League One |
| 20 | Sat 19 Feb 2022 | 155-5 v Wycombe WanderersWycombe Wanderers 5-5 Cheltenham Town | Sky Bet League One |
| 21 | Sat 26 Feb 2022 | 15 1-2 v Crewe AlexandraCheltenham Town 1-2 Crewe Alexandra | Sky Bet League One |
| 22 | Sat 5 Mar 2022 | 15 4-0 v Doncaster RoversCheltenham Town 4-0 Doncaster Rovers | Sky Bet League One |
| 23 | Tue 8 Mar 2022 | 151-3 v Milton Keynes DonsMilton Keynes Dons 3-1 Cheltenham Town | Sky Bet League One |
| 24 | Sat 12 Mar 2022 | 153-1 v MorecambeMorecambe 1-3 Cheltenham Town | Sky Bet League One |
| 25 | Sat 19 Mar 2022 | 153-1 v AFC WimbledonCheltenham Town 3-1 AFC Wimbledon | Sky Bet League One |
| 26 | Tue 22 Mar 2022 | 150-2 v Plymouth ArgylePlymouth Argyle 2-0 Cheltenham Town | Sky Bet League One |
| 27 | Sat 26 Mar 2022 | 15 1-4 v Sheffield WednesdaySheffield Wednesday 4-1 Cheltenham Town | Sky Bet League One |
| 28 | Sat 2 Apr 2022 | 15 4-4 v Accrington StanleyAccrington Stanley 4-4 Cheltenham Town | Sky Bet League One |
| 29 | Sat 9 Apr 2022 | 151-0 v PortsmouthCheltenham Town 1-0 Portsmouth | Sky Bet League One |
| 30 | Fri 15 Apr 2022 | 152-2 v GillinghamCheltenham Town 2-2 Gillingham | Sky Bet League One |
| 31 | Mon 18 Apr 2022 | 150-3 v Lincoln CityLincoln City 3-0 Cheltenham Town | Sky Bet League One |
| 32 | Sat 23 Apr 2022 | 151-2 v Bolton WanderersCheltenham Town 1-2 Bolton Wanderers | Sky Bet League One |
| 33 | Sat 30 Apr 2022 | 15 2-2 v Cambridge UnitedCambridge United 2-2 Cheltenham Town | Sky Bet League One |
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