| 1 | Sat 8 Jan 2022 | 21-0 v Birmingham CityBirmingham City 0-1 Plymouth Argyle | Emirates FA Cup Third Round |
| 2 | Sat 15 Jan 2022 | 22-4 v Sheffield WednesdaySheffield Wednesday 4-2 Plymouth Argyle | Sky Bet League One |
| 3 | Sat 29 Jan 2022 | 23-1 v Doncaster RoversDoncaster Rovers 1-3 Plymouth Argyle | Sky Bet League One |
| 4 | Sat 12 Feb 2022 | 2 1-0 v Shrewsbury TownPlymouth Argyle 1-0 Shrewsbury Town | Sky Bet League One |
| 5 | Sat 19 Feb 2022 | 22-0 v GillinghamGillingham 0-2 Plymouth Argyle | Sky Bet League One |
| 6 | Tue 22 Feb 2022 | 2 0-2 v Cambridge UnitedCambridge United 2-0 Plymouth Argyle | Sky Bet League One |
| 7 | Sat 26 Feb 2022 | 20-1 v Rotherham UnitedPlymouth Argyle 0-1 Rotherham United | Sky Bet League One |
| 8 | Sat 5 Mar 2022 | 22-0 v MorecambePlymouth Argyle 2-0 Morecambe | Sky Bet League One |
| 9 | Tue 8 Mar 2022 | 22-0 v AFC WimbledonPlymouth Argyle 2-0 AFC Wimbledon | Sky Bet League One |
| 10 | Sat 12 Mar 2022 | 21-0 v Bolton WanderersBolton Wanderers 0-1 Plymouth Argyle | Sky Bet League One |
| 11 | Tue 15 Mar 2022 | 21-0 v PortsmouthPlymouth Argyle 1-0 Portsmouth | Sky Bet League One |
| 12 | Sat 19 Mar 2022 | 24-0 v Accrington StanleyPlymouth Argyle 4-0 Accrington Stanley | Sky Bet League One |
| 13 | Tue 22 Mar 2022 | 22-0 v Cheltenham TownPlymouth Argyle 2-0 Cheltenham Town | Sky Bet League One |
| 14 | Sat 26 Mar 2022 | 20-1 v Ipswich TownIpswich Town 1-0 Plymouth Argyle | Sky Bet League One |
| 15 | Sat 2 Apr 2022 | 21-0 v Oxford UnitedPlymouth Argyle 1-0 Oxford United | Sky Bet League One |
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