| 1 | Sat 7 Aug 2021 | 72-1 v Doncaster RoversDoncaster Rovers 1-2 AFC Wimbledon | Sky Bet League One |
| 2 | Tue 10 Aug 2021 | 71-0 v Charlton AthleticCharlton Athletic 0-1 AFC Wimbledon | Carabao Cup First Round |
| 3 | Sat 14 Aug 2021 | 73-3 v Bolton WanderersAFC Wimbledon 3-3 Bolton Wanderers | Sky Bet League One |
| 4 | Sat 21 Aug 2021 | 70-1 v SunderlandSunderland 1-0 AFC Wimbledon | Sky Bet League One |
| 5 | Sat 28 Aug 2021 | 72-2 v Ipswich TownIpswich Town 2-2 AFC Wimbledon | Sky Bet League One |
| 6 | Tue 7 Sep 2021 | 75-3 v PortsmouthAFC Wimbledon 5-3 Portsmouth | Papa John’s Trophy |
| 7 | Sat 11 Sep 2021 | 74-3 v MorecambeMorecambe 3-4 AFC Wimbledon | Sky Bet League One |
| 8 | Sat 18 Sep 2021 | 70-1 v Plymouth ArgyleAFC Wimbledon 0-1 Plymouth Argyle | Sky Bet League One |
| 9 | Sat 25 Sep 2021 | 71-2 v Shrewsbury TownShrewsbury Town 2-1 AFC Wimbledon | Sky Bet League One |
| 10 | Sat 2 Oct 2021 | 71-1 v Burton AlbionAFC Wimbledon 1-1 Burton Albion | Sky Bet League One |
| 11 | Sat 16 Oct 2021 | 72-2 v Sheffield WednesdayAFC Wimbledon 2-2 Sheffield Wednesday | Sky Bet League One |
| 12 | Sat 23 Oct 2021 | 70-2 v Wigan AthleticAFC Wimbledon 0-2 Wigan Athletic | Sky Bet League One |
| 13 | Sat 30 Oct 2021 | 70-1 v Cambridge UnitedCambridge United 1-0 AFC Wimbledon | Sky Bet League One |
| 14 | Sat 6 Nov 2021 | 71-0 v GuiseleyAFC Wimbledon 1-0 Guiseley | Emirates FA Cup First Round |
| 15 | Tue 11 Jan 2022 | 70-1 v Milton Keynes DonsMilton Keynes Dons 1-0 AFC Wimbledon | Sky Bet League One |
| 16 | Sat 15 Jan 2022 | 70-0 v MorecambeAFC Wimbledon 0-0 Morecambe | Sky Bet League One |
| 17 | Tue 18 Jan 2022 | 70-0 v PortsmouthAFC Wimbledon 0-0 Portsmouth | Sky Bet League One |
| 18 | Sat 22 Jan 2022 | 71-1 v Burton AlbionBurton Albion 1-1 AFC Wimbledon | Sky Bet League One |
| 19 | Tue 1 Feb 2022 | 72-2 v Cheltenham TownAFC Wimbledon 2-2 Cheltenham Town | Sky Bet League One |
| 20 | Tue 8 Feb 2022 | 70-1 v Rotherham UnitedAFC Wimbledon 0-1 Rotherham United | Sky Bet League One |
| 21 | Tue 22 Feb 2022 | 70-0 v GillinghamGillingham 0-0 AFC Wimbledon | Sky Bet League One |
| 22 | Sat 26 Feb 2022 | 72-2 v Doncaster RoversAFC Wimbledon 2-2 Doncaster Rovers | Sky Bet League One |
| 23 | Tue 8 Mar 2022 | 70-2 v Plymouth ArgylePlymouth Argyle 2-0 AFC Wimbledon | Sky Bet League One |
| 24 | Sat 12 Mar 2022 | 70-2 v Lincoln CityAFC Wimbledon 0-2 Lincoln City | Sky Bet League One |
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