1 | Sat 7 Aug 2021 | 18 1-1 v Salford CitySalford City 1-1 Leyton Orient | Sky Bet League Two |
2 | Wed 11 Aug 2021 | 181-1 v Queens Park RangersLeyton Orient 1-1 Queens Park Rangers | Carabao Cup First Round |
3 | Sat 14 Aug 2021 | 183-0 v Exeter CityLeyton Orient 3-0 Exeter City | Sky Bet League Two |
4 | Sat 21 Aug 2021 | 181-1 v Carlisle UnitedCarlisle United 1-1 Leyton Orient | Sky Bet League Two |
5 | Tue 24 Aug 2021 | 180-2 v Harrogate TownLeyton Orient 0-2 Harrogate Town | Sky Bet League Two |
6 | Sat 28 Aug 2021 | 182-0 v Bradford CityLeyton Orient 2-0 Bradford City | Sky Bet League Two |
7 | Sat 4 Sep 2021 | 182-2 v Newport CountyNewport County 2-2 Leyton Orient | Sky Bet League Two |
8 | Sat 11 Sep 2021 | 184-0 v Oldham AthleticLeyton Orient 4-0 Oldham Athletic | Sky Bet League Two |
9 | Sat 18 Sep 2021 | 18 3-1 v Bristol RoversBristol Rovers 1-3 Leyton Orient | Sky Bet League Two |
10 | Sat 25 Sep 2021 | 180-0 v Mansfield TownLeyton Orient 0-0 Mansfield Town | Sky Bet League Two |
11 | Sat 2 Oct 2021 | 182-3 v Port ValePort Vale 3-2 Leyton Orient | Sky Bet League Two |
12 | Sat 9 Oct 2021 | 181-1 v BarrowBarrow 1-1 Leyton Orient | Sky Bet League Two |
13 | Sat 16 Oct 2021 | 180-0 v WalsallLeyton Orient 0-0 Walsall | Sky Bet League Two |
14 | Tue 19 Oct 2021 | 18 1-1 v Forest Green RoversLeyton Orient 1-1 Forest Green Rovers | Sky Bet League Two |
15 | Sat 23 Oct 2021 | 180-0 v StevenageStevenage 0-0 Leyton Orient | Sky Bet League Two |
16 | Sat 30 Oct 2021 | 18 5-0 v Hartlepool UnitedLeyton Orient 5-0 Hartlepool United | Sky Bet League Two |
17 | Sat 6 Nov 2021 | 181-0 v Ebbsfleet UnitedLeyton Orient 1-0 Ebbsfleet United | Emirates FA Cup First Round |
18 | Sat 13 Nov 2021 | 182-2 v RochdaleRochdale 2-2 Leyton Orient | Sky Bet League Two |
19 | Sat 20 Nov 2021 | 184-1 v Sutton UnitedLeyton Orient 4-1 Sutton United | Sky Bet League Two |
20 | Tue 23 Nov 2021 | 181-1 v Scunthorpe UnitedScunthorpe United 1-1 Leyton Orient | Sky Bet League Two |
21 | Sat 27 Nov 2021 | 180-1 v Northampton TownNorthampton Town 1-0 Leyton Orient | Sky Bet League Two |
22 | Sat 4 Dec 2021 | 184-0 v Tranmere RoversLeyton Orient 4-0 Tranmere Rovers | Emirates FA Cup Second Round |
23 | Sat 11 Dec 2021 | 18 1-2 v Crawley TownLeyton Orient 1-2 Crawley Town | Sky Bet League Two |
24 | Sun 9 Jan 2022 | 180-2 v Stoke CityStoke City 2-0 Leyton Orient | Emirates FA Cup Third Round |
25 | Sat 22 Jan 2022 | 180-0 v Port ValeLeyton Orient 0-0 Port Vale | Sky Bet League Two |
26 | Tue 1 Feb 2022 | 181-1 v Bradford CityBradford City 1-1 Leyton Orient | Sky Bet League Two |
27 | Sat 5 Feb 2022 | 180-1 v Colchester UnitedLeyton Orient 0-1 Colchester United | Sky Bet League Two |
28 | Tue 8 Feb 2022 | 18 0-1 v Exeter CityExeter City 1-0 Leyton Orient | Sky Bet League Two |
29 | Sat 12 Feb 2022 | 180-2 v Salford CityLeyton Orient 0-2 Salford City | Sky Bet League Two |
30 | Tue 22 Feb 2022 | 18 0-2 v Bristol RoversLeyton Orient 0-2 Bristol Rovers | Sky Bet League Two |
31 | Sat 26 Feb 2022 | 180-1 v Carlisle UnitedLeyton Orient 0-1 Carlisle United | Sky Bet League Two |
32 | Tue 1 Mar 2022 | 182-2 v Colchester UnitedColchester United 2-2 Leyton Orient | Sky Bet League Two |
33 | Sat 5 Mar 2022 | 182-2 v StevenageLeyton Orient 2-2 Stevenage | Sky Bet League Two |
34 | Sat 19 Mar 2022 | 183-1 v RochdaleLeyton Orient 3-1 Rochdale | Sky Bet League Two |
35 | Tue 22 Mar 2022 | 183-0 v Harrogate TownHarrogate Town 0-3 Leyton Orient | Sky Bet League Two |
36 | Sat 26 Mar 2022 | 18 2-0 v BarrowLeyton Orient 2-0 Barrow | Sky Bet League Two |
37 | Tue 29 Mar 2022 | 18 0-2 v Oldham AthleticOldham Athletic 2-0 Leyton Orient | Sky Bet League Two |
38 | Sat 2 Apr 2022 | 182-0 v WalsallWalsall 0-2 Leyton Orient | Sky Bet League Two |
39 | Sat 9 Apr 2022 | 180-1 v Sutton UnitedSutton United 1-0 Leyton Orient | Sky Bet League Two |
40 | Mon 18 Apr 2022 | 18 2-1 v Swindon TownSwindon Town 1-2 Leyton Orient | Sky Bet League Two |
41 | Sat 23 Apr 2022 | 182-4 v Northampton TownLeyton Orient 2-4 Northampton Town | Sky Bet League Two |
42 | Sat 7 May 2022 | 180-1 v Tranmere RoversLeyton Orient 0-1 Tranmere Rovers | Sky Bet League Two |