| 1 | Sat 18 Sep 2021 | 102-1 v WalsallNewport County 2-1 Walsall | Sky Bet League Two |
| 2 | Fri 24 Sep 2021 | 101-2 v BarrowBarrow 2-1 Newport County | Sky Bet League Two |
| 3 | Sat 2 Oct 2021 | 103-0 v Scunthorpe UnitedNewport County 3-0 Scunthorpe United | Sky Bet League Two |
| 4 | Sat 9 Oct 2021 | 10 0-0 v Bradford CityNewport County 0-0 Bradford City | Sky Bet League Two |
| 5 | Sat 16 Oct 2021 | 10 2-2 v Exeter CityExeter City 2-2 Newport County | Sky Bet League Two |
| 6 | Tue 19 Oct 2021 | 102-2 v Carlisle UnitedNewport County 2-2 Carlisle United | Sky Bet League Two |
| 7 | Sat 23 Oct 2021 | 10 3-1 v Bristol RoversBristol Rovers 1-3 Newport County | Sky Bet League Two |
| 8 | Sat 30 Oct 2021 | 105-0 v StevenageNewport County 5-0 Stevenage | Sky Bet League Two |
| 9 | Sat 6 Nov 2021 | 100-1 v MorecambeMorecambe 1-0 Newport County | Emirates FA Cup First Round |
| 10 | Fri 12 Nov 2021 | 102-1 v Hartlepool UnitedHartlepool United 1-2 Newport County | Sky Bet League Two |
| 11 | Sat 20 Nov 2021 | 101-2 v Swindon TownNewport County 1-2 Swindon Town | Sky Bet League Two |
| 12 | Tue 23 Nov 2021 | 101-1 v Crawley TownCrawley Town 1-1 Newport County | Sky Bet League Two |
| 13 | Fri 26 Nov 2021 | 101-1 v Colchester UnitedColchester United 1-1 Newport County | Sky Bet League Two |
| 14 | Tue 7 Dec 2021 | 103-2 v Sutton UnitedNewport County 3-2 Sutton United | Sky Bet League Two |
| 15 | Sat 11 Dec 2021 | 102-1 v Port ValeNewport County 2-1 Port Vale | Sky Bet League Two |
| 16 | Sat 18 Dec 2021 | 100-3 v RochdaleRochdale 3-0 Newport County | Sky Bet League Two |
| 17 | Sat 1 Jan 2022 | 10 3-3 v WalsallWalsall 3-3 Newport County | Sky Bet League Two |
| 18 | Sat 8 Jan 2022 | 100-2 v Salford CityNewport County 0-2 Salford City | Sky Bet League Two |
| 19 | Sat 15 Jan 2022 | 104-0 v Harrogate TownNewport County 4-0 Harrogate Town | Sky Bet League Two |
| 20 | Sat 22 Jan 2022 | 101-0 v Scunthorpe UnitedScunthorpe United 0-1 Newport County | Sky Bet League Two |
| 21 | Tue 25 Jan 2022 | 101-0 v Leyton OrientLeyton Orient 0-1 Newport County | Sky Bet League Two |
| 22 | Sat 29 Jan 2022 | 102-1 v BarrowNewport County 2-1 Barrow | Sky Bet League Two |
| 23 | Sat 5 Feb 2022 | 100-2 v Forest Green RoversForest Green Rovers 2-0 Newport County | Sky Bet League Two |
| 24 | Tue 8 Feb 2022 | 100-1 v Northampton TownNorthampton Town 1-0 Newport County | Sky Bet League Two |
| 25 | Sat 12 Feb 2022 | 103-3 v Oldham AthleticNewport County 3-3 Oldham Athletic | Sky Bet League Two |
| 26 | Sat 19 Feb 2022 | 10 1-1 v Mansfield TownNewport County 1-1 Mansfield Town | Sky Bet League Two |
| 27 | Sat 2 Apr 2022 | 100-1 v Exeter CityNewport County 0-1 Exeter City | Sky Bet League Two |
| 28 | Sat 9 Apr 2022 | 101-0 v Swindon TownSwindon Town 0-1 Newport County | Sky Bet League Two |
| 29 | Fri 15 Apr 2022 | 101-2 v Crawley TownNewport County 1-2 Crawley Town | Sky Bet League Two |
| 30 | Mon 18 Apr 2022 | 100-1 v Sutton UnitedSutton United 1-0 Newport County | Sky Bet League Two |
| 31 | Fri 22 Apr 2022 | 101-2 v Colchester UnitedNewport County 1-2 Colchester United | Sky Bet League Two |
| 32 | Mon 2 May 2022 | 102-1 v Port ValePort Vale 1-2 Newport County | Sky Bet League Two |
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