| 1 | Sat 11 Sep 2021 | 5 1-0 v Norwich CityArsenal 1-0 Norwich City | Premier League |
| 2 | Sat 18 Sep 2021 | 51-0 v BurnleyBurnley 0-1 Arsenal | Premier League |
| 3 | Wed 22 Sep 2021 | 53-0 v AFC WimbledonArsenal 3-0 AFC Wimbledon | Carabao Cup Third Round |
| 4 | Sun 26 Sep 2021 | 53-1 v Tottenham HotspurArsenal 3-1 Tottenham Hotspur | Premier League |
| 5 | Sat 2 Oct 2021 | 5 0-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-0 Arsenal | Premier League |
| 6 | Sat 9 Oct 2021 | 63-1 v ZimbabweGhana 3-1 Zimbabwe | World Cup Qualification (Africa) Group G |
| 7 | Tue 12 Oct 2021 | 61-0 v ZimbabweZimbabwe 0-1 Ghana | World Cup Qualification (Africa) Group G |
| 8 | Mon 18 Oct 2021 | 52-2 v Crystal PalaceArsenal 2-2 Crystal Palace | Premier League |
| 9 | Fri 22 Oct 2021 | 53-1 v Aston VillaArsenal 3-1 Aston Villa | Premier League |
| 10 | Sat 30 Oct 2021 | 52-0 v Leicester CityLeicester City 0-2 Arsenal | Premier League |
| 11 | Sat 20 Nov 2021 | 50-4 v LiverpoolLiverpool 4-0 Arsenal | Premier League |
| 12 | Sat 27 Nov 2021 | 52-0 v Newcastle UnitedArsenal 2-0 Newcastle United | Premier League |
| 13 | Thu 2 Dec 2021 | 52-3 v Manchester UnitedManchester United 3-2 Arsenal | Premier League |
| 14 | Mon 6 Dec 2021 | 51-2 v EvertonEverton 2-1 Arsenal | Premier League |
| 15 | Sat 11 Dec 2021 | 53-0 v SouthamptonArsenal 3-0 Southampton | Premier League |
| 16 | Wed 15 Dec 2021 | 52-0 v West Ham UnitedArsenal 2-0 West Ham United | Premier League |
| 17 | Sat 18 Dec 2021 | 54-1 v Leeds UnitedLeeds United 1-4 Arsenal | Premier League |
| 18 | Sun 26 Dec 2021 | 5 5-0 v Norwich CityNorwich City 0-5 Arsenal | Premier League |
| 19 | Sat 1 Jan 2022 | 51-2 v Manchester CityArsenal 1-2 Manchester City | Premier League |
| 20 | Mon 10 Jan 2022 | 50-1 v MoroccoMorocco 1-0 Ghana | Africa Cup of Nations Group C |
| 21 | Fri 14 Jan 2022 | 5 1-1 v GabonGabon 1-1 Ghana | Africa Cup of Nations Group C |
| 22 | Thu 20 Jan 2022 | 5 0-2 v LiverpoolArsenal 0-2 Liverpool | Carabao Cup Semi Final |
| 23 | Thu 10 Feb 2022 | 5 1-0 v Wolverhampton WanderersWolverhampton Wanderers 0-1 Arsenal | Premier League |
| 24 | Sat 19 Feb 2022 | 52-1 v BrentfordArsenal 2-1 Brentford | Premier League |
| 25 | Thu 24 Feb 2022 | 52-1 v Wolverhampton WanderersArsenal 2-1 Wolverhampton Wanderers | Premier League |
| 26 | Sun 6 Mar 2022 | 53-2 v WatfordWatford 2-3 Arsenal | Premier League |
| 27 | Sun 13 Mar 2022 | 52-0 v Leicester CityArsenal 2-0 Leicester City | Premier League |
| 28 | Wed 16 Mar 2022 | 50-2 v LiverpoolArsenal 0-2 Liverpool | Premier League |
| 29 | Sat 19 Mar 2022 | 5 1-0 v Aston VillaAston Villa 0-1 Arsenal | Premier League |
| 30 | Fri 25 Mar 2022 | 50-0 v NigeriaGhana 0-0 Nigeria | World Cup Qualification (Africa) Third Round |
| 31 | Tue 29 Mar 2022 | 5 1-1 v NigeriaNigeria 1-1 Ghana | World Cup Qualification (Africa) Third Round |
| 32 | Mon 4 Apr 2022 | 5 0-3 v Crystal PalaceCrystal Palace 3-0 Arsenal | Premier League |
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