| 1 | Sat 14 Aug 2021 | 33-0 v Crystal PalaceChelsea 3-0 Crystal Palace | Premier League |
| 2 | Sun 22 Aug 2021 | 32-0 v ArsenalArsenal 0-2 Chelsea | Premier League |
| 3 | Sat 28 Aug 2021 | 31-1 v LiverpoolLiverpool 1-1 Chelsea | Premier League |
| 4 | Sat 11 Sep 2021 | 3 3-0 v Aston VillaChelsea 3-0 Aston Villa | Premier League |
| 5 | Tue 14 Sep 2021 | 31-0 v Zenit St PetersburgChelsea 1-0 Zenit St Petersburg | UEFA Champions League Group H |
| 6 | Sun 19 Sep 2021 | 33-0 v Tottenham HotspurTottenham Hotspur 0-3 Chelsea | Premier League |
| 7 | Sat 25 Sep 2021 | 3 0-1 v Manchester CityChelsea 0-1 Manchester City | Premier League |
| 8 | Wed 29 Sep 2021 | 3 0-1 v JuventusJuventus 1-0 Chelsea | UEFA Champions League Group H |
| 9 | Sun 10 Oct 2021 | 171-2 v FranceSpain 1-2 France | UEFA Nations League Final |
| 10 | Wed 20 Oct 2021 | 34-0 v Malmö FFChelsea 4-0 Malmö FF | UEFA Champions League Group H |
| 11 | Tue 26 Oct 2021 | 31-1 v SouthamptonChelsea 1-1 Southampton | Carabao Cup Round of 16 |
| 12 | Tue 2 Nov 2021 | 31-0 v Malmö FFMalmö FF 0-1 Chelsea | UEFA Champions League Group H |
| 13 | Sun 28 Nov 2021 | 31-1 v Manchester UnitedChelsea 1-1 Manchester United | Premier League |
| 14 | Wed 1 Dec 2021 | 3 2-1 v WatfordWatford 1-2 Chelsea | Premier League |
| 15 | Sat 4 Dec 2021 | 32-3 v West Ham UnitedWest Ham United 3-2 Chelsea | Premier League |
| 16 | Wed 8 Dec 2021 | 33-3 v Zenit St PetersburgZenit St Petersburg 3-3 Chelsea | UEFA Champions League Group H |
| 17 | Sat 11 Dec 2021 | 33-2 v Leeds UnitedChelsea 3-2 Leeds United | Premier League |
| 18 | Thu 16 Dec 2021 | 31-1 v EvertonChelsea 1-1 Everton | Premier League |
| 19 | Sun 19 Dec 2021 | 30-0 v Wolverhampton WanderersWolverhampton Wanderers 0-0 Chelsea | Premier League |
| 20 | Wed 22 Dec 2021 | 32-0 v BrentfordBrentford 0-2 Chelsea | Carabao Cup Quarter Final |
| 21 | Sun 26 Dec 2021 | 3 3-1 v Aston VillaAston Villa 1-3 Chelsea | Premier League |
| 22 | Wed 29 Dec 2021 | 31-1 v Brighton & Hove AlbionChelsea 1-1 Brighton & Hove Albion | Premier League |
| 23 | Sun 2 Jan 2022 | 32-2 v LiverpoolChelsea 2-2 Liverpool | Premier League |
| 24 | Wed 5 Jan 2022 | 32-0 v Tottenham HotspurChelsea 2-0 Tottenham Hotspur | Carabao Cup Semi Final |
| 25 | Wed 12 Jan 2022 | 31-0 v Tottenham HotspurTottenham Hotspur 0-1 Chelsea | Carabao Cup Semi Final |
| 26 | Sat 15 Jan 2022 | 3 0-1 v Manchester CityManchester City 1-0 Chelsea | Premier League |
| 27 | Tue 18 Jan 2022 | 3 1-1 v Brighton & Hove AlbionBrighton & Hove Albion 1-1 Chelsea | Premier League |
| 28 | Sun 23 Jan 2022 | 32-0 v Tottenham HotspurChelsea 2-0 Tottenham Hotspur | Premier League |
| 29 | Sat 5 Feb 2022 | 32-1 v Plymouth ArgyleChelsea 2-1 Plymouth Argyle | Emirates FA Cup Fourth Round |
| 30 | Sat 19 Feb 2022 | 31-0 v Crystal PalaceCrystal Palace 0-1 Chelsea | Premier League |
| 31 | Tue 22 Feb 2022 | 32-0 v LilleChelsea 2-0 Lille | UEFA Champions League Round of 16 |
| 32 | Sun 27 Feb 2022 | 30-0 v LiverpoolChelsea 0-0 Liverpool | Carabao Cup Final |
| 33 | Wed 16 Mar 2022 | 32-1 v LilleLille 1-2 Chelsea | UEFA Champions League Round of 16 |
| 34 | Tue 29 Mar 2022 | 175-0 v IcelandSpain 5-0 Iceland | International Friendly |
| 35 | Sat 2 Apr 2022 | 31-4 v BrentfordChelsea 1-4 Brentford | Premier League |
| 36 | Sat 9 Apr 2022 | 36-0 v SouthamptonSouthampton 0-6 Chelsea | Premier League |
| 37 | Tue 12 Apr 2022 | 33-2 v Real MadridReal Madrid 2-3 Chelsea | UEFA Champions League Quarter Final |
| 38 | Sun 17 Apr 2022 | 32-0 v Crystal PalaceChelsea 2-0 Crystal Palace | Emirates FA Cup Semi Final |
| 39 | Wed 20 Apr 2022 | 32-4 v ArsenalChelsea 2-4 Arsenal | Premier League |
| 40 | Sun 24 Apr 2022 | 3 1-0 v West Ham UnitedChelsea 1-0 West Ham United | Premier League |
| 41 | Thu 28 Apr 2022 | 31-1 v Manchester UnitedManchester United 1-1 Chelsea | Premier League |
| 42 | Sun 1 May 2022 | 3 0-1 v EvertonEverton 1-0 Chelsea | Premier League |
| 43 | Sat 7 May 2022 | 32-2 v Wolverhampton WanderersChelsea 2-2 Wolverhampton Wanderers | Premier League |
| 44 | Wed 11 May 2022 | 33-0 v Leeds UnitedLeeds United 0-3 Chelsea | Premier League |
| 45 | Sat 14 May 2022 | 30-0 v LiverpoolChelsea 0-0 Liverpool | Emirates FA Cup Final |
| 46 | Thu 19 May 2022 | 31-1 v Leicester CityChelsea 1-1 Leicester City | Premier League |
| 47 | Sun 5 Jun 2022 | 172-2 v Czech RepublicCzech Republic 2-2 Spain | UEFA Nations League League A Group 2 |
| 48 | Sun 12 Jun 2022 | 172-0 v Czech RepublicSpain 2-0 Czech Republic | UEFA Nations League League A Group 2 |
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