| 1 | Sat 14 Aug 2021 | 53-1 v SouthamptonEverton 3-1 Southampton | Premier League |
| 2 | Sat 21 Aug 2021 | 52-2 v Leeds UnitedLeeds United 2-2 Everton | Premier League |
| 3 | Tue 24 Aug 2021 | 52-1 v Huddersfield TownHuddersfield Town 1-2 Everton | Carabao Cup Second Round |
| 4 | Sat 28 Aug 2021 | 52-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-2 Everton | Premier League |
| 5 | Mon 13 Sep 2021 | 53-1 v BurnleyEverton 3-1 Burnley | Premier League |
| 6 | Sat 18 Sep 2021 | 50-3 v Aston VillaAston Villa 3-0 Everton | Premier League |
| 7 | Tue 21 Sep 2021 | 52-2 v Queens Park RangersQueens Park Rangers 2-2 Everton | Carabao Cup Third Round |
| 8 | Sat 25 Sep 2021 | 52-0 v Norwich CityEverton 2-0 Norwich City | Premier League |
| 9 | Sat 2 Oct 2021 | 51-1 v Manchester UnitedManchester United 1-1 Everton | Premier League |
| 10 | Sun 17 Oct 2021 | 50-1 v West Ham UnitedEverton 0-1 West Ham United | Premier League |
| 11 | Sat 23 Oct 2021 | 52-5 v WatfordEverton 2-5 Watford | Premier League |
| 12 | Mon 1 Nov 2021 | 51-2 v Wolverhampton WanderersWolverhampton Wanderers 2-1 Everton | Premier League |
| 13 | Sun 7 Nov 2021 | 50-0 v Tottenham HotspurEverton 0-0 Tottenham Hotspur | Premier League |
| 14 | Sun 21 Nov 2021 | 50-3 v Manchester CityManchester City 3-0 Everton | Premier League |
| 15 | Sun 28 Nov 2021 | 50-1 v BrentfordBrentford 1-0 Everton | Premier League |
| 16 | Wed 1 Dec 2021 | 51-4 v LiverpoolEverton 1-4 Liverpool | Premier League |
| 17 | Mon 6 Dec 2021 | 52-1 v ArsenalEverton 2-1 Arsenal | Premier League |
| 18 | Sun 12 Dec 2021 | 51-3 v Crystal PalaceCrystal Palace 3-1 Everton | Premier League |
| 19 | Thu 16 Dec 2021 | 51-1 v ChelseaChelsea 1-1 Everton | Premier League |
| 20 | Sun 2 Jan 2022 | 52-3 v Brighton & Hove AlbionEverton 2-3 Brighton & Hove Albion | Premier League |
| 21 | Sat 8 Jan 2022 | 53-2 v Hull CityHull City 2-3 Everton | Emirates FA Cup Third Round |
| 22 | Sat 15 Jan 2022 | 5 1-2 v Norwich CityNorwich City 2-1 Everton | Premier League |
| 23 | Sat 5 Feb 2022 | 54-1 v BrentfordEverton 4-1 Brentford | Emirates FA Cup Fourth Round |
| 24 | Tue 8 Feb 2022 | 51-3 v Newcastle UnitedNewcastle United 3-1 Everton | Premier League |
| 25 | Sat 12 Feb 2022 | 53-0 v Leeds UnitedEverton 3-0 Leeds United | Premier League |
| 26 | Sat 19 Feb 2022 | 50-2 v SouthamptonSouthampton 2-0 Everton | Premier League |
| 27 | Sat 26 Feb 2022 | 50-1 v Manchester CityEverton 0-1 Manchester City | Premier League |
| 28 | Thu 3 Mar 2022 | 52-0 v Boreham WoodEverton 2-0 Boreham Wood | Emirates FA Cup Fifth Round |
| 29 | Mon 7 Mar 2022 | 50-5 v Tottenham HotspurTottenham Hotspur 5-0 Everton | Premier League |
| 30 | Thu 17 Mar 2022 | 51-0 v Newcastle UnitedEverton 1-0 Newcastle United | Premier League |
| 31 | Sun 20 Mar 2022 | 50-4 v Crystal PalaceCrystal Palace 4-0 Everton | Emirates FA Cup Sixth Round |
| 32 | Sun 3 Apr 2022 | 5 1-2 v West Ham UnitedWest Ham United 2-1 Everton | Premier League |
| 33 | Sat 9 Apr 2022 | 51-0 v Manchester UnitedEverton 1-0 Manchester United | Premier League |
| 34 | Sun 8 May 2022 | 52-1 v Leicester CityLeicester City 1-2 Everton | Premier League |
| 35 | Wed 11 May 2022 | 50-0 v WatfordWatford 0-0 Everton | Premier League |
| 36 | Thu 19 May 2022 | 5 3-2 v Crystal PalaceEverton 3-2 Crystal Palace | Premier League |
| 37 | Sun 22 May 2022 | 51-5 v ArsenalArsenal 5-1 Everton | Premier League |
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