| 1 | Sun 1 Aug 2021 | 52-3 v HibernianMotherwell 2-3 Hibernian | Cinch Premiership |
| 2 | Sun 8 Aug 2021 | 51-1 v St JohnstoneSt Johnstone 1-1 Motherwell | Cinch Premiership |
| 3 | Sat 21 Aug 2021 | 52-1 v LivingstonLivingston 1-2 Motherwell | Cinch Premiership |
| 4 | Sat 28 Aug 2021 | 51-0 v DundeeMotherwell 1-0 Dundee | Cinch Premiership |
| 5 | Sat 11 Sep 2021 | 52-0 v AberdeenMotherwell 2-0 Aberdeen | Cinch Premiership |
| 6 | Sun 19 Sep 2021 | 51-1 v RangersRangers 1-1 Motherwell | Cinch Premiership |
| 7 | Sat 2 Oct 2021 | 50-2 v Heart of MidlothianHeart of Midlothian 2-0 Motherwell | Cinch Premiership |
| 8 | Sat 16 Oct 2021 | 5 0-2 v CelticMotherwell 0-2 Celtic | Cinch Premiership |
| 9 | Sat 23 Oct 2021 | 51-2 v Dundee UnitedDundee United 2-1 Motherwell | Cinch Premiership |
| 10 | Wed 27 Oct 2021 | 52-2 v St MirrenMotherwell 2-2 St Mirren | Cinch Premiership |
| 11 | Sun 31 Oct 2021 | 5 1-6 v RangersMotherwell 1-6 Rangers | Cinch Premiership |
| 12 | Sat 6 Nov 2021 | 5 2-0 v AberdeenAberdeen 0-2 Motherwell | Cinch Premiership |
| 13 | Thu 11 Nov 2021 | 51-1 v KenyaUganda 1-1 Kenya | World Cup Qualification (Africa) Group E |
| 14 | Sun 14 Nov 2021 | 5 0-1 v MaliMali 1-0 Uganda | World Cup Qualification (Africa) Group E |
| 15 | Sat 20 Nov 2021 | 52-0 v Heart of MidlothianMotherwell 2-0 Heart of Midlothian | Cinch Premiership |
| 16 | Sat 27 Nov 2021 | 5 0-3 v DundeeDundee 3-0 Motherwell | Cinch Premiership |
| 17 | Tue 30 Nov 2021 | 51-0 v Dundee UnitedMotherwell 1-0 Dundee United | Cinch Premiership |
| 18 | Sat 4 Dec 2021 | 51-1 v HibernianHibernian 1-1 Motherwell | Cinch Premiership |
| 19 | Sun 12 Dec 2021 | 50-1 v CelticCeltic 1-0 Motherwell | Cinch Premiership |
| 20 | Sat 18 Dec 2021 | 52-0 v St JohnstoneMotherwell 2-0 St Johnstone | Cinch Premiership |
| 21 | Sun 26 Dec 2021 | 52-1 v LivingstonMotherwell 2-1 Livingston | Cinch Premiership |
| 22 | Tue 18 Jan 2022 | 51-3 v Ross CountyRoss County 3-1 Motherwell | Cinch Premiership |
| 23 | Tue 1 Feb 2022 | 51-1 v St MirrenSt Mirren 1-1 Motherwell | Cinch Premiership |
| 24 | Sun 6 Feb 2022 | 5 0-4 v CelticMotherwell 0-4 Celtic | Cinch Premiership |
| 25 | Wed 9 Feb 2022 | 50-2 v Dundee UnitedDundee United 2-0 Motherwell | Cinch Premiership |
| 26 | Sat 12 Feb 2022 | 52-1 v AberdeenMotherwell 2-1 Aberdeen | William Hill Scottish Cup Fifth Round |
| 27 | Sat 19 Feb 2022 | 5 1-1 v AberdeenMotherwell 1-1 Aberdeen | Cinch Premiership |
| 28 | Sun 27 Feb 2022 | 52-2 v RangersRangers 2-2 Motherwell | Cinch Premiership |
| 29 | Sun 13 Mar 2022 | 5 1-2 v HibernianMotherwell 1-2 Hibernian | William Hill Scottish Cup Quarter Final |
| 30 | Sat 2 Apr 2022 | 54-2 v St MirrenMotherwell 4-2 St Mirren | Cinch Premiership |
| 31 | Sat 9 Apr 2022 | 52-2 v LivingstonLivingston 2-2 Motherwell | Cinch Premiership |
| 32 | Sat 23 Apr 2022 | 5 1-3 v RangersMotherwell 1-3 Rangers | Cinch Premiership |
| 33 | Sat 30 Apr 2022 | 5 0-1 v Dundee UnitedDundee United 1-0 Motherwell | Cinch Premiership |
| 34 | Wed 11 May 2022 | 52-1 v Heart of MidlothianMotherwell 2-1 Heart of Midlothian | Cinch Premiership |
| 35 | Sat 14 May 2022 | 50-6 v CelticCeltic 6-0 Motherwell | Cinch Premiership |
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