| 1 | Sat 21 Aug 2021 | 60-0 v VillarrealEspanyol 0-0 Villarreal | Spanish La Liga |
| 2 | Fri 27 Aug 2021 | 6 0-1 v MallorcaMallorca 1-0 Espanyol | Spanish La Liga |
| 3 | Sun 12 Sep 2021 | 61-2 v Atlético MadridEspanyol 1-2 Atlético Madrid | Spanish La Liga |
| 4 | Sun 19 Sep 2021 | 6 2-2 v Real BetisReal Betis 2-2 Espanyol | Spanish La Liga |
| 5 | Wed 22 Sep 2021 | 61-0 v AlavésEspanyol 1-0 Alavés | Spanish La Liga |
| 6 | Sun 3 Oct 2021 | 62-1 v Real MadridEspanyol 2-1 Real Madrid | Spanish La Liga |
| 7 | Mon 18 Oct 2021 | 62-0 v CádizEspanyol 2-0 Cádiz | Spanish La Liga |
| 8 | Sat 23 Oct 2021 | 62-2 v ElcheElche 2-2 Espanyol | Spanish La Liga |
| 9 | Tue 26 Oct 2021 | 61-1 v Athletic BilbaoEspanyol 1-1 Athletic Bilbao | Spanish La Liga |
| 10 | Sun 31 Oct 2021 | 61-2 v GetafeGetafe 2-1 Espanyol | Spanish La Liga |
| 11 | Sat 6 Nov 2021 | 62-0 v GranadaEspanyol 2-0 Granada | Spanish La Liga |
| 12 | Sat 20 Nov 2021 | 60-1 v BarcelonaBarcelona 1-0 Espanyol | Spanish La Liga |
| 13 | Sun 28 Nov 2021 | 61-0 v Real SociedadEspanyol 1-0 Real Sociedad | Spanish La Liga |
| 14 | Sun 5 Dec 2021 | 60-1 v Rayo VallecanoRayo Vallecano 1-0 Espanyol | Spanish La Liga |
| 15 | Sat 11 Dec 2021 | 64-3 v LevanteEspanyol 4-3 Levante | Spanish La Liga |
| 16 | Fri 17 Dec 2021 | 61-3 v Celta VigoCelta Vigo 3-1 Espanyol | Spanish La Liga |
| 17 | Fri 31 Dec 2021 | 62-1 v ValenciaValencia 1-2 Espanyol | Spanish La Liga |
| 18 | Mon 10 Jan 2022 | 61-2 v ElcheEspanyol 1-2 Elche | Spanish La Liga |
| 19 | Tue 18 Jan 2022 | 62-2 v CádizCádiz 2-2 Espanyol | Spanish La Liga |
| 20 | Fri 21 Jan 2022 | 6 1-4 v Real BetisEspanyol 1-4 Real Betis | Spanish La Liga |
| 21 | Mon 7 Feb 2022 | 6 1-2 v Athletic BilbaoAthletic Bilbao 2-1 Espanyol | Spanish La Liga |
| 22 | Sun 13 Feb 2022 | 6 2-2 v BarcelonaEspanyol 2-2 Barcelona | Spanish La Liga |
| 23 | Sun 20 Mar 2022 | 6 1-0 v MallorcaEspanyol 1-0 Mallorca | Spanish La Liga |
| 24 | Sun 17 Apr 2022 | 6 1-2 v Atlético MadridAtlético Madrid 2-1 Espanyol | Spanish La Liga |
| 25 | Thu 21 Apr 2022 | 60-1 v Rayo VallecanoEspanyol 0-1 Rayo Vallecano | Spanish La Liga |
| 26 | Sat 30 Apr 2022 | 60-4 v Real MadridReal Madrid 4-0 Espanyol | Spanish La Liga |
| 27 | Sun 8 May 2022 | 61-1 v OsasunaEspanyol 1-1 Osasuna | Spanish La Liga |
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