| 1 | Sat 14 Aug 2021 | 81-1 v Real BetisMallorca 1-1 Real Betis | Spanish La Liga |
| 2 | Sat 21 Aug 2021 | 81-0 v AlavésAlavés 0-1 Mallorca | Spanish La Liga |
| 3 | Fri 27 Aug 2021 | 81-0 v EspanyolMallorca 1-0 Espanyol | Spanish La Liga |
| 4 | Sun 19 Sep 2021 | 80-0 v VillarrealMallorca 0-0 Villarreal | Spanish La Liga |
| 5 | Sun 26 Sep 2021 | 82-3 v OsasunaMallorca 2-3 Osasuna | Spanish La Liga |
| 6 | Sat 16 Oct 2021 | 80-1 v Real SociedadReal Sociedad 1-0 Mallorca | Spanish La Liga |
| 7 | Wed 27 Oct 2021 | 81-1 v SevillaMallorca 1-1 Sevilla | Spanish La Liga |
| 8 | Sun 31 Oct 2021 | 81-1 v CádizCádiz 1-1 Mallorca | Spanish La Liga |
| 9 | Sun 7 Nov 2021 | 82-2 v ElcheMallorca 2-2 Elche | Spanish La Liga |
| 10 | Sun 19 Dec 2021 | 81-4 v GranadaGranada 4-1 Mallorca | Spanish La Liga |
| 11 | Sat 8 Jan 2022 | 80-2 v LevanteLevante 2-0 Mallorca | Spanish La Liga |
| 12 | Sat 22 Jan 2022 | 80-3 v VillarrealVillarreal 3-0 Mallorca | Spanish La Liga |
| 13 | Sat 5 Feb 2022 | 82-1 v CádizMallorca 2-1 Cádiz | Spanish La Liga |
| 14 | Mon 14 Feb 2022 | 83-2 v Athletic BilbaoMallorca 3-2 Athletic Bilbao | Spanish La Liga |
| 15 | Sun 20 Feb 2022 | 81-2 v Real BetisReal Betis 2-1 Mallorca | Spanish La Liga |
| 16 | Sat 26 Feb 2022 | 80-1 v ValenciaMallorca 0-1 Valencia | Spanish La Liga |
| 17 | Wed 2 Mar 2022 | 80-2 v Real SociedadMallorca 0-2 Real Sociedad | Spanish La Liga |
| 18 | Sun 6 Mar 2022 | 83-4 v Celta VigoCelta Vigo 4-3 Mallorca | Spanish La Liga |
| 19 | Mon 14 Mar 2022 | 80-3 v Real MadridMallorca 0-3 Real Madrid | Spanish La Liga |
| 20 | Sun 20 Mar 2022 | 80-1 v EspanyolEspanyol 1-0 Mallorca | Spanish La Liga |
| 21 | Sat 2 Apr 2022 | 8 0-1 v GetafeGetafe 1-0 Mallorca | Spanish La Liga |
| 22 | Sat 16 Apr 2022 | 80-3 v ElcheElche 3-0 Mallorca | Spanish La Liga |
| 23 | Tue 19 Apr 2022 | 82-1 v AlavésMallorca 2-1 Alavés | Spanish La Liga |
| 24 | Sun 1 May 2022 | 81-2 v BarcelonaBarcelona 2-1 Mallorca | Spanish La Liga |
| 25 | Sat 7 May 2022 | 82-6 v GranadaMallorca 2-6 Granada | Spanish La Liga |
| 26 | Wed 11 May 2022 | 8 0-0 v SevillaSevilla 0-0 Mallorca | Spanish La Liga |
| 27 | Sun 15 May 2022 | 82-1 v Rayo VallecanoMallorca 2-1 Rayo Vallecano | Spanish La Liga |
| 28 | Sun 22 May 2022 | 82-0 v OsasunaOsasuna 0-2 Mallorca | Spanish La Liga |
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