| 1 | Sat 30 Jul 2022 | 20-0 v Birmingham CityLuton Town 0-0 Birmingham City | Sky Bet Championship |
| 2 | Sat 6 Aug 2022 | 21-1 v BurnleyBurnley 1-1 Luton Town | Sky Bet Championship |
| 3 | Sat 13 Aug 2022 | 20-1 v Preston North EndLuton Town 0-1 Preston North End | Sky Bet Championship |
| 4 | Tue 16 Aug 2022 | 20-2 v Bristol CityBristol City 2-0 Luton Town | Sky Bet Championship |
| 5 | Sat 20 Aug 2022 | 22-0 v Swansea CitySwansea City 0-2 Luton Town | Sky Bet Championship |
| 6 | Fri 26 Aug 2022 | 21-1 v Sheffield UnitedLuton Town 1-1 Sheffield United | Sky Bet Championship |
| 7 | Tue 30 Aug 2022 | 22-1 v Cardiff CityCardiff City 1-2 Luton Town | Sky Bet Championship |
| 8 | Sat 3 Sep 2022 | 21-2 v Wigan AthleticLuton Town 1-2 Wigan Athletic | Sky Bet Championship |
| 9 | Wed 14 Sep 2022 | 22-2 v Coventry CityLuton Town 2-2 Coventry City | Sky Bet Championship |
| 10 | Sat 17 Sep 2022 | 22-0 v Blackburn RoversLuton Town 2-0 Blackburn Rovers | Sky Bet Championship |
| 11 | Fri 30 Sep 2022 | 2 2-0 v Hull CityHull City 0-2 Luton Town | Sky Bet Championship |
| 12 | Tue 4 Oct 2022 | 23-3 v Huddersfield TownLuton Town 3-3 Huddersfield Town | Sky Bet Championship |
| 13 | Sat 8 Oct 2022 | 20-0 v West Bromwich AlbionWest Bromwich Albion 0-0 Luton Town | Sky Bet Championship |
| 14 | Sat 15 Oct 2022 | 23-1 v Queens Park RangersLuton Town 3-1 Queens Park Rangers | Sky Bet Championship |
| 15 | Tue 18 Oct 2022 | 21-0 v Norwich CityNorwich City 0-1 Luton Town | Sky Bet Championship |
| 16 | Sun 23 Oct 2022 | 20-4 v WatfordWatford 4-0 Luton Town | Sky Bet Championship |
| 17 | Sat 29 Oct 2022 | 21-1 v SunderlandLuton Town 1-1 Sunderland | Sky Bet Championship |
| 18 | Tue 1 Nov 2022 | 20-0 v ReadingLuton Town 0-0 Reading | Sky Bet Championship |
| 19 | Sat 5 Nov 2022 | 21-0 v BlackpoolBlackpool 0-1 Luton Town | Sky Bet Championship |
| 20 | Tue 8 Nov 2022 | 20-2 v Stoke CityStoke City 2-0 Luton Town | Sky Bet Championship |
| 21 | Sat 12 Nov 2022 | 21-1 v Rotherham UnitedLuton Town 1-1 Rotherham United | Sky Bet Championship |
| 22 | Sat 10 Dec 2022 | 2 1-2 v MiddlesbroughMiddlesbrough 2-1 Luton Town | Sky Bet Championship |
| 23 | Mon 26 Dec 2022 | 22-1 v Norwich CityLuton Town 2-1 Norwich City | Sky Bet Championship |
| 24 | Thu 29 Dec 2022 | 23-0 v Queens Park RangersQueens Park Rangers 0-3 Luton Town | Sky Bet Championship |
| 25 | Sun 1 Jan 2023 | 22-1 v Huddersfield TownHuddersfield Town 1-2 Luton Town | Sky Bet Championship |
| 26 | Sat 7 Jan 2023 | 21-1 v Wigan AthleticLuton Town 1-1 Wigan Athletic | Emirates FA Cup Third Round |
| 27 | Sat 14 Jan 2023 | 2 2-3 v West Bromwich AlbionLuton Town 2-3 West Bromwich Albion | Sky Bet Championship |
| 28 | Tue 17 Jan 2023 | 22-1 v Wigan AthleticWigan Athletic 1-2 Luton Town | Emirates FA Cup Third Round |
| 29 | Sat 21 Jan 2023 | 22-0 v Wigan AthleticWigan Athletic 0-2 Luton Town | Sky Bet Championship |
| 30 | Tue 31 Jan 2023 | 141-2 v Newcastle UnitedNewcastle United 2-1 Southampton | Carabao Cup Semi Final |
| 31 | Sat 4 Feb 2023 | 140-3 v BrentfordBrentford 3-0 Southampton | Premier League |
| 32 | Sat 11 Feb 2023 | 141-2 v Wolverhampton WanderersSouthampton 1-2 Wolverhampton Wanderers | Premier League |
| 33 | Wed 15 Mar 2023 | 140-2 v BrentfordSouthampton 0-2 Brentford | Premier League |
| 34 | Sun 21 May 2023 | 14 1-3 v Brighton & Hove AlbionBrighton & Hove Albion 3-1 Southampton | Premier League |
| 35 | Sun 28 May 2023 | 144-4 v LiverpoolSouthampton 4-4 Liverpool | Premier League |
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