| 1 | Sat 30 Jul 2022 | 40-0 v Preston North EndWigan Athletic 0-0 Preston North End | Sky Bet Championship |
| 2 | Sat 6 Aug 2022 | 41-1 v Norwich CityNorwich City 1-1 Wigan Athletic | Sky Bet Championship |
| 3 | Sat 13 Aug 2022 | 41-1 v Bristol CityWigan Athletic 1-1 Bristol City | Sky Bet Championship |
| 4 | Sat 20 Aug 2022 | 4 1-0 v Birmingham CityBirmingham City 0-1 Wigan Athletic | Sky Bet Championship |
| 5 | Sat 27 Aug 2022 | 41-5 v BurnleyWigan Athletic 1-5 Burnley | Sky Bet Championship |
| 6 | Tue 30 Aug 2022 | 41-1 v West Bromwich AlbionWigan Athletic 1-1 West Bromwich Albion | Sky Bet Championship |
| 7 | Sat 3 Sep 2022 | 42-1 v Luton TownLuton Town 1-2 Wigan Athletic | Sky Bet Championship |
| 8 | Tue 13 Sep 2022 | 42-1 v Huddersfield TownHuddersfield Town 1-2 Wigan Athletic | Sky Bet Championship |
| 9 | Sat 17 Sep 2022 | 4 0-1 v ReadingWigan Athletic 0-1 Reading | Sky Bet Championship |
| 10 | Sat 1 Oct 2022 | 42-0 v Rotherham UnitedRotherham United 0-2 Wigan Athletic | Sky Bet Championship |
| 11 | Wed 5 Oct 2022 | 41-2 v Hull CityHull City 2-1 Wigan Athletic | Sky Bet Championship |
| 12 | Sat 8 Oct 2022 | 41-3 v Cardiff CityWigan Athletic 1-3 Cardiff City | Sky Bet Championship |
| 13 | Tue 11 Oct 2022 | 4 1-0 v Blackburn RoversWigan Athletic 1-0 Blackburn Rovers | Sky Bet Championship |
| 14 | Sat 15 Oct 2022 | 41-2 v SunderlandSunderland 2-1 Wigan Athletic | Sky Bet Championship |
| 15 | Sat 22 Oct 2022 | 41-2 v Queens Park RangersQueens Park Rangers 2-1 Wigan Athletic | Sky Bet Championship |
| 16 | Sat 29 Oct 2022 | 40-1 v WatfordWigan Athletic 0-1 Watford | Sky Bet Championship |
| 17 | Wed 2 Nov 2022 | 4 0-1 v Stoke CityWigan Athletic 0-1 Stoke City | Sky Bet Championship |
| 18 | Sat 5 Nov 2022 | 42-2 v Swansea CitySwansea City 2-2 Wigan Athletic | Sky Bet Championship |
| 19 | Sat 12 Nov 2022 | 42-1 v BlackpoolWigan Athletic 2-1 Blackpool | Sky Bet Championship |
| 20 | Sat 10 Dec 2022 | 41-1 v MillwallMillwall 1-1 Wigan Athletic | Sky Bet Championship |
| 21 | Mon 19 Dec 2022 | 41-2 v Sheffield UnitedWigan Athletic 1-2 Sheffield United | Sky Bet Championship |
| 22 | Mon 26 Dec 2022 | 41-4 v MiddlesbroughMiddlesbrough 4-1 Wigan Athletic | Sky Bet Championship |
| 23 | Thu 29 Dec 2022 | 41-4 v SunderlandWigan Athletic 1-4 Sunderland | Sky Bet Championship |
| 24 | Mon 2 Jan 2023 | 41-4 v Hull CityWigan Athletic 1-4 Hull City | Sky Bet Championship |
| 25 | Sat 7 Jan 2023 | 41-1 v Luton TownLuton Town 1-1 Wigan Athletic | Emirates FA Cup Third Round |
| 26 | Sat 14 Jan 2023 | 41-1 v Cardiff CityCardiff City 1-1 Wigan Athletic | Sky Bet Championship |
| 27 | Tue 17 Jan 2023 | 41-2 v Luton TownWigan Athletic 1-2 Luton Town | Emirates FA Cup Third Round |
| 28 | Sat 21 Jan 2023 | 40-2 v Luton TownWigan Athletic 0-2 Luton Town | Sky Bet Championship |
| 29 | Sat 11 Feb 2023 | 41-0 v Huddersfield TownWigan Athletic 1-0 Huddersfield Town | Sky Bet Championship |
| 30 | Wed 15 Feb 2023 | 41-1 v Bristol CityBristol City 1-1 Wigan Athletic | Sky Bet Championship |
| 31 | Sat 11 Mar 2023 | 40-3 v BurnleyBurnley 3-0 Wigan Athletic | Sky Bet Championship |
| 32 | Sat 18 Mar 2023 | 41-1 v WatfordWatford 1-1 Wigan Athletic | Sky Bet Championship |
| 33 | Sat 1 Apr 2023 | 41-0 v Queens Park RangersWigan Athletic 1-0 Queens Park Rangers | Sky Bet Championship |
| 34 | Fri 7 Apr 2023 | 40-1 v Sheffield UnitedSheffield United 1-0 Wigan Athletic | Sky Bet Championship |
| 35 | Mon 10 Apr 2023 | 40-2 v Swansea CityWigan Athletic 0-2 Swansea City | Sky Bet Championship |
| 36 | Sat 15 Apr 2023 | 40-1 v BlackpoolBlackpool 1-0 Wigan Athletic | Sky Bet Championship |
| 37 | Tue 18 Apr 2023 | 41-0 v Stoke CityStoke City 0-1 Wigan Athletic | Sky Bet Championship |
| 38 | Sat 22 Apr 2023 | 42-1 v MillwallWigan Athletic 2-1 Millwall | Sky Bet Championship |
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