| 1 | Sat 13 Aug 2022 | 4 2-2 v RB LeipzigRB Leipzig 2-2 1 FC Köln | German Bundesliga |
| 2 | Thu 18 Aug 2022 | 41-2 v Videoton FC Fehervar1 FC Köln 1-2 Videoton FC Fehervar | UEFA Europa Conference League Play-off |
| 3 | Sun 21 Aug 2022 | 41-1 v Eintracht FrankfurtEintracht Frankfurt 1-1 1 FC Köln | German Bundesliga |
| 4 | Thu 25 Aug 2022 | 43-0 v Videoton FC FehervarVideoton FC Fehervar 0-3 1 FC Köln | UEFA Europa Conference League Play-off |
| 5 | Sun 28 Aug 2022 | 40-0 v VfB Stuttgart1 FC Köln 0-0 VfB Stuttgart | German Bundesliga |
| 6 | Sat 3 Sep 2022 | 44-2 v VfL WolfsburgVfL Wolfsburg 2-4 1 FC Köln | German Bundesliga |
| 7 | Thu 8 Sep 2022 | 4 1-1 v NiceNice 1-1 1 FC Köln | UEFA Europa Conference League Group D |
| 8 | Sun 11 Sep 2022 | 40-1 v 1 FC Union Berlin1 FC Köln 0-1 1 FC Union Berlin | German Bundesliga |
| 9 | Thu 15 Sep 2022 | 44-2 v Slovácko1 FC Köln 4-2 Slovácko | UEFA Europa Conference League Group D |
| 10 | Sun 18 Sep 2022 | 4 1-1 v VfL BochumVfL Bochum 1-1 1 FC Köln | German Bundesliga |
| 11 | Sat 1 Oct 2022 | 4 3-2 v Borussia Dortmund1 FC Köln 3-2 Borussia Dortmund | German Bundesliga |
| 12 | Sun 9 Oct 2022 | 42-5 v Borussia MönchengladbachBorussia Mönchengladbach 5-2 1 FC Köln | German Bundesliga |
| 13 | Thu 13 Oct 2022 | 4 0-2 v FK PartizanFK Partizan 2-0 1 FC Köln | UEFA Europa Conference League Group D |
| 14 | Sun 16 Oct 2022 | 43-2 v FC Augsburg1 FC Köln 3-2 FC Augsburg | German Bundesliga |
| 15 | Fri 21 Oct 2022 | 40-5 v Mainz 05Mainz 05 5-0 1 FC Köln | German Bundesliga |
| 16 | Sun 30 Oct 2022 | 41-1 v 1899 Hoffenheim1 FC Köln 1-1 1899 Hoffenheim | German Bundesliga |
| 17 | Thu 3 Nov 2022 | 4 2-2 v Nice1 FC Köln 2-2 Nice | UEFA Europa Conference League Group D |
| 18 | Sat 12 Nov 2022 | 40-2 v Hertha BerlinHertha Berlin 2-0 1 FC Köln | German Bundesliga |
| 19 | Sat 21 Jan 2023 | 47-1 v Werder Bremen1 FC Köln 7-1 Werder Bremen | German Bundesliga |
| 20 | Sun 29 Jan 2023 | 4 0-0 v FC Schalke 04FC Schalke 04 0-0 1 FC Köln | German Bundesliga |
| 21 | Sat 4 Feb 2023 | 40-0 v RB Leipzig1 FC Köln 0-0 RB Leipzig | German Bundesliga |
| 22 | Sun 12 Feb 2023 | 4 3-0 v Eintracht Frankfurt1 FC Köln 3-0 Eintracht Frankfurt | German Bundesliga |
| 23 | Sat 25 Feb 2023 | 40-2 v VfL Wolfsburg1 FC Köln 0-2 VfL Wolfsburg | German Bundesliga |
| 24 | Sat 4 Mar 2023 | 40-0 v 1 FC Union Berlin1 FC Union Berlin 0-0 1 FC Köln | German Bundesliga |
| 25 | Fri 10 Mar 2023 | 40-2 v VfL Bochum1 FC Köln 0-2 VfL Bochum | German Bundesliga |
| 26 | Sat 18 Mar 2023 | 41-6 v Borussia DortmundBorussia Dortmund 6-1 1 FC Köln | German Bundesliga |
| 27 | Sun 2 Apr 2023 | 40-0 v Borussia Mönchengladbach1 FC Köln 0-0 Borussia Mönchengladbach | German Bundesliga |
| 28 | Sat 8 Apr 2023 | 4 3-1 v FC AugsburgFC Augsburg 1-3 1 FC Köln | German Bundesliga |
| 29 | Sat 15 Apr 2023 | 4 1-1 v Mainz 051 FC Köln 1-1 Mainz 05 | German Bundesliga |
| 30 | Sat 22 Apr 2023 | 43-1 v 1899 Hoffenheim1899 Hoffenheim 1-3 1 FC Köln | German Bundesliga |
| 31 | Sat 29 Apr 2023 | 40-1 v SC Freiburg1 FC Köln 0-1 SC Freiburg | German Bundesliga |
| 32 | Fri 5 May 2023 | 42-1 v Bayer 04 LeverkusenBayer 04 Leverkusen 1-2 1 FC Köln | German Bundesliga |
| 33 | Fri 12 May 2023 | 4 5-2 v Hertha Berlin1 FC Köln 5-2 Hertha Berlin | German Bundesliga |
| 34 | Sat 20 May 2023 | 41-1 v Werder BremenWerder Bremen 1-1 1 FC Köln | German Bundesliga |
| 35 | Sat 27 May 2023 | 41-2 v Bayern Munich1 FC Köln 1-2 Bayern Munich | German Bundesliga |
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