| 1 | Fri 5 Aug 2022 | 11-6 v Bayern MunichEintracht Frankfurt 1-6 Bayern Munich | German Bundesliga |
| 2 | Wed 10 Aug 2022 | 10-2 v Real MadridReal Madrid 2-0 Eintracht Frankfurt | UEFA Super Cup Final |
| 3 | Sat 13 Aug 2022 | 11-1 v Hertha BerlinHertha Berlin 1-1 Eintracht Frankfurt | German Bundesliga |
| 4 | Sun 21 Aug 2022 | 11-1 v 1 FC KölnEintracht Frankfurt 1-1 1 FC Köln | German Bundesliga |
| 5 | Sun 28 Aug 2022 | 1 4-3 v Werder BremenWerder Bremen 3-4 Eintracht Frankfurt | German Bundesliga |
| 6 | Sat 3 Sep 2022 | 14-0 v RB LeipzigEintracht Frankfurt 4-0 RB Leipzig | German Bundesliga |
| 7 | Wed 7 Sep 2022 | 10-3 v Sporting LisbonEintracht Frankfurt 0-3 Sporting Lisbon | UEFA Champions League Group D |
| 8 | Sat 10 Sep 2022 | 10-1 v VfL WolfsburgEintracht Frankfurt 0-1 VfL Wolfsburg | German Bundesliga |
| 9 | Tue 13 Sep 2022 | 11-0 v MarseilleMarseille 0-1 Eintracht Frankfurt | UEFA Champions League Group D |
| 10 | Sat 17 Sep 2022 | 13-1 v VfB StuttgartVfB Stuttgart 1-3 Eintracht Frankfurt | German Bundesliga |
| 11 | Sat 1 Oct 2022 | 12-0 v 1 FC Union BerlinEintracht Frankfurt 2-0 1 FC Union Berlin | German Bundesliga |
| 12 | Tue 4 Oct 2022 | 10-0 v Tottenham HotspurEintracht Frankfurt 0-0 Tottenham Hotspur | UEFA Champions League Group D |
| 13 | Sat 8 Oct 2022 | 10-3 v VfL BochumVfL Bochum 3-0 Eintracht Frankfurt | German Bundesliga |
| 14 | Wed 12 Oct 2022 | 12-3 v Tottenham HotspurTottenham Hotspur 3-2 Eintracht Frankfurt | UEFA Champions League Group D |
| 15 | Sat 15 Oct 2022 | 15-1 v Bayer 04 LeverkusenEintracht Frankfurt 5-1 Bayer 04 Leverkusen | German Bundesliga |
| 16 | Sat 22 Oct 2022 | 13-1 v Borussia MönchengladbachBorussia Mönchengladbach 1-3 Eintracht Frankfurt | German Bundesliga |
| 17 | Wed 26 Oct 2022 | 12-1 v MarseilleEintracht Frankfurt 2-1 Marseille | UEFA Champions League Group D |
| 18 | Sat 29 Oct 2022 | 1 1-2 v Borussia DortmundEintracht Frankfurt 1-2 Borussia Dortmund | German Bundesliga |
| 19 | Tue 1 Nov 2022 | 12-1 v Sporting LisbonSporting Lisbon 1-2 Eintracht Frankfurt | UEFA Champions League Group D |
| 20 | Sat 5 Nov 2022 | 12-1 v FC AugsburgFC Augsburg 1-2 Eintracht Frankfurt | German Bundesliga |
| 21 | Wed 9 Nov 2022 | 14-2 v 1899 HoffenheimEintracht Frankfurt 4-2 1899 Hoffenheim | German Bundesliga |
| 22 | Sun 13 Nov 2022 | 11-1 v Mainz 05Mainz 05 1-1 Eintracht Frankfurt | German Bundesliga |
| 23 | Sat 21 Jan 2023 | 13-0 v FC Schalke 04Eintracht Frankfurt 3-0 FC Schalke 04 | German Bundesliga |
| 24 | Sat 28 Jan 2023 | 11-1 v Bayern MunichBayern Munich 1-1 Eintracht Frankfurt | German Bundesliga |
| 25 | Sat 4 Feb 2023 | 13-0 v Hertha BerlinEintracht Frankfurt 3-0 Hertha Berlin | German Bundesliga |
| 26 | Sun 12 Feb 2023 | 10-3 v 1 FC Köln1 FC Köln 3-0 Eintracht Frankfurt | German Bundesliga |
| 27 | Sat 18 Feb 2023 | 12-0 v Werder BremenEintracht Frankfurt 2-0 Werder Bremen | German Bundesliga |
| 28 | Tue 21 Feb 2023 | 10-2 v NapoliEintracht Frankfurt 0-2 Napoli | UEFA Champions League Round of 16 |
| 29 | Sat 25 Feb 2023 | 11-2 v RB LeipzigRB Leipzig 2-1 Eintracht Frankfurt | German Bundesliga |
| 30 | Sun 5 Mar 2023 | 12-2 v VfL WolfsburgVfL Wolfsburg 2-2 Eintracht Frankfurt | German Bundesliga |
| 31 | Sat 11 Mar 2023 | 11-1 v VfB StuttgartEintracht Frankfurt 1-1 VfB Stuttgart | German Bundesliga |
| 32 | Wed 15 Mar 2023 | 10-3 v NapoliNapoli 3-0 Eintracht Frankfurt | UEFA Champions League Round of 16 |
| 33 | Sun 19 Mar 2023 | 10-2 v 1 FC Union Berlin1 FC Union Berlin 2-0 Eintracht Frankfurt | German Bundesliga |
| 34 | Fri 31 Mar 2023 | 11-1 v VfL BochumEintracht Frankfurt 1-1 VfL Bochum | German Bundesliga |
| 35 | Sat 8 Apr 2023 | 11-3 v Bayer 04 LeverkusenBayer 04 Leverkusen 3-1 Eintracht Frankfurt | German Bundesliga |
| 36 | Sat 15 Apr 2023 | 11-1 v Borussia MönchengladbachEintracht Frankfurt 1-1 Borussia Mönchengladbach | German Bundesliga |
| 37 | Sat 22 Apr 2023 | 10-4 v Borussia DortmundBorussia Dortmund 4-0 Eintracht Frankfurt | German Bundesliga |
| 38 | Sat 29 Apr 2023 | 11-1 v FC AugsburgEintracht Frankfurt 1-1 FC Augsburg | German Bundesliga |
| 39 | Sat 6 May 2023 | 1 1-3 v 1899 Hoffenheim1899 Hoffenheim 3-1 Eintracht Frankfurt | German Bundesliga |
| 40 | Sat 13 May 2023 | 13-0 v Mainz 05Eintracht Frankfurt 3-0 Mainz 05 | German Bundesliga |
| 41 | Sat 20 May 2023 | 12-2 v FC Schalke 04FC Schalke 04 2-2 Eintracht Frankfurt | German Bundesliga |
| 42 | Sat 27 May 2023 | 12-1 v SC FreiburgEintracht Frankfurt 2-1 SC Freiburg | German Bundesliga |
| 43 | Mon 12 Jun 2023 | 123-3 v UkraineGermany 3-3 Ukraine | International Friendly |
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