| 1 | Sat 30 Jul 2022 | 42 0-1 v Derby CountyDerby County 1-0 Oxford United | Sky Bet League One |
| 2 | Sat 6 Aug 2022 | 421-0 v Cambridge UnitedOxford United 1-0 Cambridge United | Sky Bet League One |
| 3 | Tue 9 Aug 2022 | 422-2 v Swansea CityOxford United 2-2 Swansea City | Carabao Cup First Round |
| 4 | Sat 13 Aug 2022 | 42 0-1 v Bristol RoversBristol Rovers 1-0 Oxford United | Sky Bet League One |
| 5 | Tue 16 Aug 2022 | 42 1-2 v Lincoln CityOxford United 1-2 Lincoln City | Sky Bet League One |
| 6 | Sat 20 Aug 2022 | 421-1 v MorecambeOxford United 1-1 Morecambe | Sky Bet League One |
| 7 | Tue 23 Aug 2022 | 420-2 v Crystal PalaceOxford United 0-2 Crystal Palace | Carabao Cup Second Round |
| 8 | Sat 27 Aug 2022 | 422-1 v Cheltenham TownCheltenham Town 1-2 Oxford United | Sky Bet League One |
| 9 | Tue 13 Sep 2022 | 420-1 v Plymouth ArgylePlymouth Argyle 1-0 Oxford United | Sky Bet League One |
| 10 | Tue 18 Oct 2022 | 420-2 v Sutton UnitedSutton United 2-0 Oxford United | Papa John’s Trophy Southern Group G |
| 11 | Tue 25 Oct 2022 | 421-1 v PortsmouthPortsmouth 1-1 Oxford United | Sky Bet League One |
| 12 | Sat 29 Oct 2022 | 42 3-1 v Bolton WanderersBolton Wanderers 1-3 Oxford United | Sky Bet League One |
| 13 | Tue 1 Nov 2022 | 42 1-1 v Fleetwood TownOxford United 1-1 Fleetwood Town | Sky Bet League One |
| 14 | Sat 12 Nov 2022 | 424-0 v Port ValeOxford United 4-0 Port Vale | Sky Bet League One |
| 15 | Wed 16 Nov 2022 | 422-1 v WokingWoking 1-2 Oxford United | Emirates FA Cup First Round |
| 16 | Sat 19 Nov 2022 | 421-1 v Forest Green RoversOxford United 1-1 Forest Green Rovers | Sky Bet League One |
| 17 | Thu 29 Dec 2022 | 423-1 v Charlton AthleticOxford United 3-1 Charlton Athletic | Sky Bet League One |
| 18 | Sat 7 Jan 2023 | 42 1-2 v Bristol RoversCambridge United 1-2 Bristol Rovers | Sky Bet League One |
| 19 | Sat 4 Mar 2023 | 420-1 v PortsmouthCambridge United 0-1 Portsmouth | Sky Bet League One |
| 20 | Tue 7 Mar 2023 | 421-1 v MorecambeCambridge United 1-1 Morecambe | Sky Bet League One |
| 21 | Sat 11 Mar 2023 | 42 0-1 v Milton Keynes DonsMilton Keynes Dons 1-0 Cambridge United | Sky Bet League One |
| 22 | Sat 18 Mar 2023 | 42 1-2 v Charlton AthleticCambridge United 1-2 Charlton Athletic | Sky Bet League One |
| 23 | Fri 7 Apr 2023 | 422-1 v Fleetwood TownCambridge United 2-1 Fleetwood Town | Sky Bet League One |
| 24 | Mon 10 Apr 2023 | 421-1 v Bolton WanderersBolton Wanderers 1-1 Cambridge United | Sky Bet League One |
| 25 | Tue 18 Apr 2023 | 421-2 v Wycombe WanderersCambridge United 1-2 Wycombe Wanderers | Sky Bet League One |
| 26 | Sat 22 Apr 2023 | 421-3 v Plymouth ArgylePlymouth Argyle 3-1 Cambridge United | Sky Bet League One |
| 27 | Sat 29 Apr 2023 | 422-1 v Accrington StanleyAccrington Stanley 1-2 Cambridge United | Sky Bet League One |
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