| 1 | Sat 30 Jul 2022 | 63-3 v Sheffield WednesdaySheffield Wednesday 3-3 Portsmouth | Sky Bet League One |
| 2 | Sat 6 Aug 2022 | 60-0 v Lincoln CityPortsmouth 0-0 Lincoln City | Sky Bet League One |
| 3 | Sat 13 Aug 2022 | 62-0 v Cheltenham TownCheltenham Town 0-2 Portsmouth | Sky Bet League One |
| 4 | Tue 16 Aug 2022 | 64-1 v Cambridge UnitedPortsmouth 4-1 Cambridge United | Sky Bet League One |
| 5 | Sat 20 Aug 2022 | 63-1 v Bristol RoversPortsmouth 3-1 Bristol Rovers | Sky Bet League One |
| 6 | Tue 23 Aug 2022 | 62-3 v Newport CountyNewport County 3-2 Portsmouth | Carabao Cup Second Round |
| 7 | Sat 27 Aug 2022 | 61-0 v Port ValePort Vale 0-1 Portsmouth | Sky Bet League One |
| 8 | Tue 13 Sep 2022 | 62-0 v Burton AlbionBurton Albion 0-2 Portsmouth | Sky Bet League One |
| 9 | Sat 17 Sep 2022 | 62-2 v Plymouth ArgylePortsmouth 2-2 Plymouth Argyle | Sky Bet League One |
| 10 | Sat 1 Oct 2022 | 62-3 v Ipswich TownIpswich Town 3-2 Portsmouth | Sky Bet League One |
| 11 | Sat 8 Oct 2022 | 61-1 v Fleetwood TownPortsmouth 1-1 Fleetwood Town | Sky Bet League One |
| 12 | Mon 17 Oct 2022 | 60-3 v Charlton AthleticCharlton Athletic 3-0 Portsmouth | Sky Bet League One |
| 13 | Sat 22 Oct 2022 | 61-0 v Forest Green RoversForest Green Rovers 0-1 Portsmouth | Sky Bet League One |
| 14 | Tue 25 Oct 2022 | 61-1 v Oxford UnitedPortsmouth 1-1 Oxford United | Sky Bet League One |
| 15 | Sat 29 Oct 2022 | 61-1 v Shrewsbury TownPortsmouth 1-1 Shrewsbury Town | Sky Bet League One |
| 16 | Tue 1 Nov 2022 | 61-1 v AFC WimbledonPortsmouth 1-1 AFC Wimbledon | Papa John’s Trophy Northern Group A |
| 17 | Fri 4 Nov 2022 | 63-1 v HerefordHereford 1-3 Portsmouth | Emirates FA Cup First Round |
| 18 | Sat 12 Nov 2022 | 61-1 v MorecambeMorecambe 1-1 Portsmouth | Sky Bet League One |
| 19 | Fri 18 Nov 2022 | 60-0 v Derby CountyPortsmouth 0-0 Derby County | Sky Bet League One |
| 20 | Tue 22 Nov 2022 | 62-0 v Ipswich TownIpswich Town 0-2 Portsmouth | Papa John’s Trophy Second Round |
| 21 | Sat 26 Nov 2022 | 63-2 v Milton Keynes DonsPortsmouth 3-2 Milton Keynes Dons | Emirates FA Cup Second Round |
| 22 | Sun 4 Dec 2022 | 6 0-2 v Wycombe WanderersWycombe Wanderers 2-0 Portsmouth | Sky Bet League One |
| 23 | Tue 13 Dec 2022 | 63-0 v StevenagePortsmouth 3-0 Stevenage | Papa John’s Trophy Third Round |
| 24 | Sat 17 Dec 2022 | 6 0-2 v Milton Keynes DonsPortsmouth 0-2 Milton Keynes Dons | Sky Bet League One |
| 25 | Thu 29 Dec 2022 | 62-2 v Ipswich TownPortsmouth 2-2 Ipswich Town | Sky Bet League One |
| 26 | Sun 1 Jan 2023 | 61-3 v Charlton AthleticPortsmouth 1-3 Charlton Athletic | Sky Bet League One |
| 27 | Sat 7 Jan 2023 | 60-1 v Tottenham HotspurTottenham Hotspur 1-0 Portsmouth | Emirates FA Cup Third Round |
| 28 | Tue 10 Jan 2023 | 60-1 v Bolton WanderersBolton Wanderers 1-0 Portsmouth | Papa John’s Trophy Northern Group D |
| 29 | Sat 14 Jan 2023 | 60-3 v Bolton WanderersBolton Wanderers 3-0 Portsmouth | Sky Bet League One |
| 30 | Sat 21 Jan 2023 | 62-0 v Exeter CityPortsmouth 2-0 Exeter City | Sky Bet League One |
| 31 | Tue 24 Jan 2023 | 6 2-0 v Fleetwood TownFleetwood Town 0-2 Portsmouth | Sky Bet League One |
| 32 | Sat 28 Jan 2023 | 61-2 v Peterborough UnitedPeterborough United 2-1 Portsmouth | Sky Bet League One |
| 33 | Sat 4 Feb 2023 | 61-1 v BarnsleyPortsmouth 1-1 Barnsley | Sky Bet League One |
| 34 | Sat 11 Feb 2023 | 61-3 v Plymouth ArgylePlymouth Argyle 3-1 Portsmouth | Sky Bet League One |
| 35 | Tue 14 Feb 2023 | 61-0 v Burton AlbionPortsmouth 1-0 Burton Albion | Sky Bet League One |
| 36 | Sat 18 Feb 2023 | 60-0 v Lincoln CityLincoln City 0-0 Portsmouth | Sky Bet League One |
| 37 | Sat 25 Feb 2023 | 6 4-0 v Cheltenham TownPortsmouth 4-0 Cheltenham Town | Sky Bet League One |
| 38 | Tue 28 Feb 2023 | 63-1 v Bolton WanderersPortsmouth 3-1 Bolton Wanderers | Sky Bet League One |
| 39 | Sat 4 Mar 2023 | 61-0 v Cambridge UnitedCambridge United 0-1 Portsmouth | Sky Bet League One |
| 40 | Tue 7 Mar 2023 | 61-3 v BarnsleyBarnsley 3-1 Portsmouth | Sky Bet League One |
| 41 | Sat 11 Mar 2023 | 60-1 v Sheffield WednesdayPortsmouth 0-1 Sheffield Wednesday | Sky Bet League One |
| 42 | Tue 14 Mar 2023 | 63-1 v Accrington StanleyAccrington Stanley 1-3 Portsmouth | Sky Bet League One |
| 43 | Sat 18 Mar 2023 | 62-0 v Bristol RoversBristol Rovers 0-2 Portsmouth | Sky Bet League One |
| 44 | Sat 25 Mar 2023 | 62-2 v Port ValePortsmouth 2-2 Port Vale | Sky Bet League One |
| 45 | Sat 1 Apr 2023 | 61-0 v Forest Green RoversPortsmouth 1-0 Forest Green Rovers | Sky Bet League One |
| 46 | Fri 7 Apr 2023 | 6 1-1 v Milton Keynes DonsMilton Keynes Dons 1-1 Portsmouth | Sky Bet League One |
| 47 | Sat 15 Apr 2023 | 61-1 v Shrewsbury TownShrewsbury Town 1-1 Portsmouth | Sky Bet League One |
| 48 | Tue 18 Apr 2023 | 61-1 v Oxford UnitedOxford United 1-1 Portsmouth | Sky Bet League One |
| 49 | Sat 22 Apr 2023 | 61-0 v Accrington StanleyPortsmouth 1-0 Accrington Stanley | Sky Bet League One |
| 50 | Sat 29 Apr 2023 | 61-1 v Derby CountyDerby County 1-1 Portsmouth | Sky Bet League One |
| 51 | Sun 7 May 2023 | 62-2 v Wycombe WanderersPortsmouth 2-2 Wycombe Wanderers | Sky Bet League One |
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