| 1 | Tue 9 Aug 2022 | 162-2 v Norwich CityNorwich City 2-2 Birmingham City | Carabao Cup First Round |
| 2 | Sat 20 Aug 2022 | 160-1 v Wigan AthleticBirmingham City 0-1 Wigan Athletic | Sky Bet Championship |
| 3 | Sat 27 Aug 2022 | 160-2 v Rotherham UnitedRotherham United 2-0 Birmingham City | Sky Bet Championship |
| 4 | Sat 3 Sep 2022 | 163-2 v Derby CountyDerby County 2-3 Plymouth Argyle | Sky Bet League One |
| 5 | Tue 13 Sep 2022 | 161-0 v Oxford UnitedPlymouth Argyle 1-0 Oxford United | Sky Bet League One |
| 6 | Sat 17 Sep 2022 | 162-2 v PortsmouthPortsmouth 2-2 Plymouth Argyle | Sky Bet League One |
| 7 | Tue 20 Sep 2022 | 16 3-1 v Swindon TownSwindon Town 1-3 Plymouth Argyle | Papa John’s Trophy |
| 8 | Sun 25 Sep 2022 | 162-1 v Ipswich TownPlymouth Argyle 2-1 Ipswich Town | Sky Bet League One |
| 9 | Sat 1 Oct 2022 | 161-0 v Wycombe WanderersWycombe Wanderers 0-1 Plymouth Argyle | Sky Bet League One |
| 10 | Tue 4 Oct 2022 | 162-1 v Sheffield WednesdayPlymouth Argyle 2-1 Sheffield Wednesday | Sky Bet League One |
| 11 | Sat 8 Oct 2022 | 16 3-0 v Accrington StanleyPlymouth Argyle 3-0 Accrington Stanley | Sky Bet League One |
| 12 | Sat 15 Oct 2022 | 164-1 v Milton Keynes DonsMilton Keynes Dons 1-4 Plymouth Argyle | Sky Bet League One |
| 13 | Tue 25 Oct 2022 | 16 2-1 v Shrewsbury TownPlymouth Argyle 2-1 Shrewsbury Town | Sky Bet League One |
| 14 | Mon 31 Oct 2022 | 164-2 v Exeter CityPlymouth Argyle 4-2 Exeter City | Sky Bet League One |
| 15 | Sat 5 Nov 2022 | 161-5 v Grimsby TownGrimsby Town 5-1 Plymouth Argyle | Emirates FA Cup First Round |
| 16 | Sat 12 Nov 2022 | 161-1 v Lincoln CityLincoln City 1-1 Plymouth Argyle | Sky Bet League One |
| 17 | Sat 19 Nov 2022 | 162-2 v Burton AlbionBurton Albion 2-2 Plymouth Argyle | Sky Bet League One |
| 18 | Tue 22 Nov 2022 | 163-2 v Charlton AthleticPlymouth Argyle 3-2 Charlton Athletic | Papa John’s Trophy Second Round |
| 19 | Fri 2 Dec 2022 | 160-2 v Port ValePlymouth Argyle 0-2 Port Vale | Sky Bet League One |
| 20 | Sat 10 Dec 2022 | 16 0-0 v Cambridge UnitedCambridge United 0-0 Plymouth Argyle | Sky Bet League One |
| 21 | Sat 17 Dec 2022 | 162-1 v MorecambePlymouth Argyle 2-1 Morecambe | Sky Bet League One |
| 22 | Wed 21 Dec 2022 | 16 3-3 v AFC WimbledonPlymouth Argyle 3-3 AFC Wimbledon | Papa John’s Trophy Third Round |
| 23 | Mon 26 Dec 2022 | 161-0 v Cheltenham TownCheltenham Town 0-1 Plymouth Argyle | Sky Bet League One |
| 24 | Thu 29 Dec 2022 | 161-0 v Wycombe WanderersPlymouth Argyle 1-0 Wycombe Wanderers | Sky Bet League One |
| 25 | Sun 1 Jan 2023 | 163-1 v Milton Keynes DonsPlymouth Argyle 3-1 Milton Keynes Dons | Sky Bet League One |
| 26 | Sat 7 Jan 2023 | 160-0 v Bolton WanderersBolton Wanderers 0-0 Plymouth Argyle | Sky Bet League One |
| 27 | Sat 14 Jan 2023 | 161-1 v Ipswich TownIpswich Town 1-1 Plymouth Argyle | Sky Bet League One |
| 28 | Sat 21 Jan 2023 | 164-2 v Cheltenham TownPlymouth Argyle 4-2 Cheltenham Town | Sky Bet League One |
| 29 | Sat 4 Feb 2023 | 160-1 v Sheffield WednesdaySheffield Wednesday 1-0 Plymouth Argyle | Sky Bet League One |
| 30 | Sat 11 Feb 2023 | 163-1 v PortsmouthPlymouth Argyle 3-1 Portsmouth | Sky Bet League One |
| 31 | Tue 14 Feb 2023 | 16 3-1 v Oxford UnitedOxford United 1-3 Plymouth Argyle | Sky Bet League One |
| 32 | Sat 18 Feb 2023 | 160-0 v Fleetwood TownPlymouth Argyle 0-0 Fleetwood Town | Sky Bet League One |
| 33 | Tue 21 Feb 2023 | 161-1 v Cheltenham TownPlymouth Argyle 1-1 Cheltenham Town | Papa John’s Trophy Northern Group E |
| 34 | Sat 25 Feb 2023 | 16 2-5 v Peterborough UnitedPeterborough United 5-2 Plymouth Argyle | Sky Bet League One |
| 35 | Sat 4 Mar 2023 | 162-0 v Charlton AthleticPlymouth Argyle 2-0 Charlton Athletic | Sky Bet League One |
| 36 | Sun 2 Apr 2023 | 16 0-4 v Bolton WanderersBolton Wanderers 4-0 Plymouth Argyle | Papa John’s Trophy Final |
| 37 | Fri 7 Apr 2023 | 163-1 v MorecambeMorecambe 1-3 Plymouth Argyle | Sky Bet League One |
| 38 | Mon 10 Apr 2023 | 160-2 v Lincoln CityPlymouth Argyle 0-2 Lincoln City | Sky Bet League One |
| 39 | Sat 15 Apr 2023 | 161-0 v Exeter CityExeter City 0-1 Plymouth Argyle | Sky Bet League One |
| 40 | Tue 18 Apr 2023 | 16 2-1 v Shrewsbury TownShrewsbury Town 1-2 Plymouth Argyle | Sky Bet League One |
| 41 | Sat 22 Apr 2023 | 163-1 v Cambridge UnitedPlymouth Argyle 3-1 Cambridge United | Sky Bet League One |
| 42 | Tue 25 Apr 2023 | 162-0 v Bristol RoversPlymouth Argyle 2-0 Bristol Rovers | Sky Bet League One |
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