| 1 | Sat 20 Aug 2022 | 13-0 v BarnsleyBarnsley 0-3 Wycombe Wanderers | Sky Bet League One |
| 2 | Sat 27 Aug 2022 | 11-1 v Charlton AthleticWycombe Wanderers 1-1 Charlton Athletic | Sky Bet League One |
| 3 | Sat 3 Sep 2022 | 1 1-1 v Fleetwood TownFleetwood Town 1-1 Wycombe Wanderers | Sky Bet League One |
| 4 | Tue 13 Sep 2022 | 11-0 v Accrington StanleyWycombe Wanderers 1-0 Accrington Stanley | Sky Bet League One |
| 5 | Sat 17 Sep 2022 | 11-2 v Derby CountyDerby County 2-1 Wycombe Wanderers | Sky Bet League One |
| 6 | Sat 24 Sep 2022 | 11-3 v Sheffield WednesdaySheffield Wednesday 3-1 Wycombe Wanderers | Sky Bet League One |
| 7 | Sat 1 Oct 2022 | 10-1 v Plymouth ArgyleWycombe Wanderers 0-1 Plymouth Argyle | Sky Bet League One |
| 8 | Sat 8 Oct 2022 | 11-0 v Oxford UnitedOxford United 0-1 Wycombe Wanderers | Sky Bet League One |
| 9 | Sat 15 Oct 2022 | 13-1 v Peterborough UnitedWycombe Wanderers 3-1 Peterborough United | Sky Bet League One |
| 10 | Tue 18 Oct 2022 | 11-1 v Peterborough UnitedWycombe Wanderers 1-1 Peterborough United | Papa John’s Trophy Southern Group D |
| 11 | Sat 22 Oct 2022 | 11-0 v Milton Keynes DonsMilton Keynes Dons 0-1 Wycombe Wanderers | Sky Bet League One |
| 12 | Tue 25 Oct 2022 | 12-3 v Cambridge UnitedWycombe Wanderers 2-3 Cambridge United | Sky Bet League One |
| 13 | Sat 29 Oct 2022 | 1 1-1 v MorecambeWycombe Wanderers 1-1 Morecambe | Sky Bet League One |
| 14 | Tue 1 Nov 2022 | 12-2 v Port ValeWycombe Wanderers 2-2 Port Vale | Sky Bet League One |
| 15 | Sat 5 Nov 2022 | 10-2 v WalsallWycombe Wanderers 0-2 Walsall | Emirates FA Cup First Round |
| 16 | Sat 12 Nov 2022 | 12-0 v Forest Green RoversForest Green Rovers 0-2 Wycombe Wanderers | Sky Bet League One |
| 17 | Sat 19 Nov 2022 | 10-1 v Cheltenham TownCheltenham Town 1-0 Wycombe Wanderers | Sky Bet League One |
| 18 | Sun 4 Dec 2022 | 12-0 v PortsmouthWycombe Wanderers 2-0 Portsmouth | Sky Bet League One |
| 19 | Sat 10 Dec 2022 | 10-0 v Lincoln CityLincoln City 0-0 Wycombe Wanderers | Sky Bet League One |
| 20 | Sat 17 Dec 2022 | 11-0 v Ipswich TownWycombe Wanderers 1-0 Ipswich Town | Sky Bet League One |
| 21 | Mon 26 Dec 2022 | 12-1 v Bristol RoversWycombe Wanderers 2-1 Bristol Rovers | Sky Bet League One |
| 22 | Thu 29 Dec 2022 | 10-1 v Plymouth ArgylePlymouth Argyle 1-0 Wycombe Wanderers | Sky Bet League One |
| 23 | Sun 1 Jan 2023 | 13-0 v Peterborough UnitedPeterborough United 0-3 Wycombe Wanderers | Sky Bet League One |
| 24 | Sat 14 Jan 2023 | 10-1 v Sheffield WednesdayWycombe Wanderers 0-1 Sheffield Wednesday | Sky Bet League One |
| 25 | Tue 24 Jan 2023 | 1 2-0 v Oxford UnitedWycombe Wanderers 2-0 Oxford United | Sky Bet League One |
| 26 | Sat 4 Feb 2023 | 13-0 v Port ValePort Vale 0-3 Wycombe Wanderers | Sky Bet League One |
| 27 | Sat 11 Feb 2023 | 1 3-2 v Derby CountyWycombe Wanderers 3-2 Derby County | Sky Bet League One |
| 28 | Tue 14 Feb 2023 | 12-0 v Accrington StanleyAccrington Stanley 0-2 Wycombe Wanderers | Sky Bet League One |
| 29 | Sat 18 Feb 2023 | 11-0 v Bolton WanderersWycombe Wanderers 1-0 Bolton Wanderers | Sky Bet League One |
| 30 | Sat 25 Feb 2023 | 10-2 v Shrewsbury TownShrewsbury Town 2-0 Wycombe Wanderers | Sky Bet League One |
| 31 | Sat 4 Mar 2023 | 11-1 v Exeter CityWycombe Wanderers 1-1 Exeter City | Sky Bet League One |
| 32 | Tue 7 Mar 2023 | 12-0 v Fleetwood TownWycombe Wanderers 2-0 Fleetwood Town | Sky Bet League One |
| 33 | Sat 11 Mar 2023 | 11-2 v Burton AlbionBurton Albion 2-1 Wycombe Wanderers | Sky Bet League One |
| 34 | Tue 14 Mar 2023 | 12-0 v Bristol RoversBristol Rovers 0-2 Wycombe Wanderers | Sky Bet League One |
| 35 | Sat 18 Mar 2023 | 10-1 v BarnsleyWycombe Wanderers 0-1 Barnsley | Sky Bet League One |
| 36 | Sat 25 Mar 2023 | 11-1 v Charlton AthleticCharlton Athletic 1-1 Wycombe Wanderers | Sky Bet League One |
| 37 | Sat 1 Apr 2023 | 12-2 v Milton Keynes DonsWycombe Wanderers 2-2 Milton Keynes Dons | Sky Bet League One |
| 38 | Fri 7 Apr 2023 | 10-4 v Ipswich TownIpswich Town 4-0 Wycombe Wanderers | Sky Bet League One |
| 39 | Mon 10 Apr 2023 | 12-0 v Forest Green RoversWycombe Wanderers 2-0 Forest Green Rovers | Sky Bet League One |
| 40 | Sat 15 Apr 2023 | 10-1 v MorecambeMorecambe 1-0 Wycombe Wanderers | Sky Bet League One |
| 41 | Tue 18 Apr 2023 | 12-1 v Cambridge UnitedCambridge United 1-2 Wycombe Wanderers | Sky Bet League One |
| 42 | Sat 22 Apr 2023 | 10-2 v Lincoln CityWycombe Wanderers 0-2 Lincoln City | Sky Bet League One |
| 43 | Sun 7 May 2023 | 12-2 v PortsmouthPortsmouth 2-2 Wycombe Wanderers | Sky Bet League One |
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