| 1 | Sat 30 Jul 2022 | 29 0-2 v Leyton OrientLeyton Orient 2-0 Grimsby Town | Sky Bet League Two |
| 2 | Sat 6 Aug 2022 | 291-1 v Northampton TownGrimsby Town 1-1 Northampton Town | Sky Bet League Two |
| 3 | Sat 13 Aug 2022 | 291-0 v RochdaleRochdale 0-1 Grimsby Town | Sky Bet League Two |
| 4 | Sat 20 Aug 2022 | 290-0 v Sutton UnitedGrimsby Town 0-0 Sutton United | Sky Bet League Two |
| 5 | Tue 23 Aug 2022 | 290-3 v Nottingham ForestGrimsby Town 0-3 Nottingham Forest | Carabao Cup Second Round |
| 6 | Sat 27 Aug 2022 | 292-1 v WalsallWalsall 1-2 Grimsby Town | Sky Bet League Two |
| 7 | Sat 3 Sep 2022 | 292-0 v Newport CountyNewport County 0-2 Grimsby Town | Sky Bet League Two |
| 8 | Tue 13 Sep 2022 | 291-1 v GillinghamGrimsby Town 1-1 Gillingham | Sky Bet League Two |
| 9 | Sat 17 Sep 2022 | 291-0 v Colchester UnitedColchester United 0-1 Grimsby Town | Sky Bet League Two |
| 10 | Sat 24 Sep 2022 | 291-2 v Swindon TownGrimsby Town 1-2 Swindon Town | Sky Bet League Two |
| 11 | Sat 8 Oct 2022 | 29 3-0 v Crawley TownGrimsby Town 3-0 Crawley Town | Sky Bet League Two |
| 12 | Sat 15 Oct 2022 | 29 3-1 v Stockport CountyStockport County 1-3 Grimsby Town | Sky Bet League Two |
| 13 | Sat 22 Oct 2022 | 290-0 v Bradford CityGrimsby Town 0-0 Bradford City | Sky Bet League Two |
| 14 | Tue 25 Oct 2022 | 290-1 v BarrowBarrow 1-0 Grimsby Town | Sky Bet League Two |
| 15 | Sat 29 Oct 2022 | 291-2 v Hartlepool UnitedHartlepool United 2-1 Grimsby Town | Sky Bet League Two |
| 16 | Sat 18 Feb 2023 | 29 2-1 v Northampton TownNorthampton Town 1-2 Grimsby Town | Sky Bet League Two |
| 17 | Wed 1 Mar 2023 | 292-1 v SouthamptonSouthampton 1-2 Grimsby Town | Emirates FA Cup Fifth Round |
| 18 | Sat 4 Mar 2023 | 290-2 v Carlisle UnitedCarlisle United 2-0 Grimsby Town | Sky Bet League Two |
| 19 | Tue 7 Mar 2023 | 291-1 v Newport CountyGrimsby Town 1-1 Newport County | Sky Bet League Two |
| 20 | Sat 11 Mar 2023 | 291-0 v RochdaleGrimsby Town 1-0 Rochdale | Sky Bet League Two |
| 21 | Tue 14 Mar 2023 | 291-0 v Sutton UnitedSutton United 0-1 Grimsby Town | Sky Bet League Two |
| 22 | Sun 19 Mar 2023 | 290-5 v Brighton & Hove AlbionBrighton & Hove Albion 5-0 Grimsby Town | Emirates FA Cup Quarter Final |
| 23 | Wed 22 Mar 2023 | 290-0 v Mansfield TownMansfield Town 0-0 Grimsby Town | Sky Bet League Two |
| 24 | Sat 25 Mar 2023 | 291-1 v WalsallGrimsby Town 1-1 Walsall | Sky Bet League Two |
| 25 | Sat 1 Apr 2023 | 292-3 v Bradford CityBradford City 3-2 Grimsby Town | Sky Bet League Two |
| 26 | Fri 7 Apr 2023 | 29 1-4 v Hartlepool UnitedGrimsby Town 1-4 Hartlepool United | Sky Bet League Two |
| 27 | Mon 10 Apr 2023 | 29 2-1 v Doncaster RoversDoncaster Rovers 1-2 Grimsby Town | Sky Bet League Two |
| 28 | Sat 15 Apr 2023 | 291-1 v Mansfield TownGrimsby Town 1-1 Mansfield Town | Sky Bet League Two |
| 29 | Sat 22 Apr 2023 | 290-2 v Tranmere RoversTranmere Rovers 2-0 Grimsby Town | Sky Bet League Two |
| 30 | Sat 29 Apr 2023 | 290-2 v StevenageStevenage 2-0 Grimsby Town | Sky Bet League Two |
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