| 1 | Sat 6 Aug 2022 | 30-0 v AFC WimbledonHartlepool United 0-0 AFC Wimbledon | Sky Bet League Two |
| 2 | Sat 13 Aug 2022 | 31-2 v Northampton TownNorthampton Town 2-1 Hartlepool United | Sky Bet League Two |
| 3 | Tue 16 Aug 2022 | 30-0 v Tranmere RoversHartlepool United 0-0 Tranmere Rovers | Sky Bet League Two |
| 4 | Sat 20 Aug 2022 | 31-3 v Bradford CityHartlepool United 1-3 Bradford City | Sky Bet League Two |
| 5 | Sat 27 Aug 2022 | 32-4 v Leyton OrientLeyton Orient 4-2 Hartlepool United | Sky Bet League Two |
| 6 | Sat 17 Sep 2022 | 30-2 v Sutton UnitedSutton United 2-0 Hartlepool United | Sky Bet League Two |
| 7 | Tue 20 Sep 2022 | 30-0 v MorecambeMorecambe 0-0 Hartlepool United | Papa John’s Trophy |
| 8 | Sat 24 Sep 2022 | 30-0 v GillinghamHartlepool United 0-0 Gillingham | Sky Bet League Two |
| 9 | Fri 30 Sep 2022 | 32-2 v Mansfield TownMansfield Town 2-2 Hartlepool United | Sky Bet League Two |
| 10 | Tue 4 Oct 2022 | 32-1 v Doncaster RoversHartlepool United 2-1 Doncaster Rovers | Sky Bet League Two |
| 11 | Sat 8 Oct 2022 | 31-3 v Carlisle UnitedHartlepool United 1-3 Carlisle United | Sky Bet League Two |
| 12 | Sat 15 Oct 2022 | 31-2 v Harrogate TownHarrogate Town 2-1 Hartlepool United | Sky Bet League Two |
| 13 | Sat 22 Oct 2022 | 31-2 v Swindon TownSwindon Town 2-1 Hartlepool United | Sky Bet League Two |
| 14 | Tue 25 Oct 2022 | 30-2 v Salford CityHartlepool United 0-2 Salford City | Sky Bet League Two |
| 15 | Sat 29 Oct 2022 | 32-1 v Grimsby TownHartlepool United 2-1 Grimsby Town | Sky Bet League Two |
| 16 | Sat 12 Nov 2022 | 30-1 v StevenageStevenage 1-0 Hartlepool United | Sky Bet League Two |
| 17 | Tue 15 Nov 2022 | 31-1 v Solihull MoorsHartlepool United 1-1 Solihull Moors | Emirates FA Cup First Round Replay |
| 18 | Sat 19 Nov 2022 | 31-3 v BarrowBarrow 3-1 Hartlepool United | Sky Bet League Two |
| 19 | Sat 26 Nov 2022 | 33-1 v Harrogate TownHartlepool United 3-1 Harrogate Town | Emirates FA Cup Second Round |
| 20 | Sat 3 Dec 2022 | 30-5 v Stockport CountyHartlepool United 0-5 Stockport County | Sky Bet League Two |
| 21 | Fri 9 Dec 2022 | 32-0 v Crawley TownCrawley Town 0-2 Hartlepool United | Sky Bet League Two |
| 22 | Mon 26 Dec 2022 | 32-1 v RochdaleRochdale 1-2 Hartlepool United | Sky Bet League Two |
| 23 | Thu 29 Dec 2022 | 31-2 v Mansfield TownHartlepool United 1-2 Mansfield Town | Sky Bet League Two |
| 24 | Sun 1 Jan 2023 | 33-3 v Harrogate TownHartlepool United 3-3 Harrogate Town | Sky Bet League Two |
| 25 | Sun 8 Jan 2023 | 30-3 v Stoke CityHartlepool United 0-3 Stoke City | Emirates FA Cup Third Round |
| 26 | Sat 14 Jan 2023 | 30-2 v GillinghamGillingham 2-0 Hartlepool United | Sky Bet League Two |
| 27 | Sat 21 Jan 2023 | 32-0 v RochdaleHartlepool United 2-0 Rochdale | Sky Bet League Two |
| 28 | Tue 24 Jan 2023 | 31-3 v Carlisle UnitedCarlisle United 3-1 Hartlepool United | Sky Bet League Two |
| 29 | Sat 28 Jan 2023 | 31-2 v Colchester UnitedHartlepool United 1-2 Colchester United | Sky Bet League Two |
| 30 | Sat 4 Feb 2023 | 31-0 v Doncaster RoversDoncaster Rovers 0-1 Hartlepool United | Sky Bet League Two |
| 31 | Sat 11 Feb 2023 | 3 2-2 v Sutton UnitedHartlepool United 2-2 Sutton United | Sky Bet League Two |
| 32 | Tue 14 Feb 2023 | 30-2 v Crewe AlexandraCrewe Alexandra 2-0 Hartlepool United | Sky Bet League Two |
| 33 | Sat 18 Feb 2023 | 32-2 v AFC WimbledonAFC Wimbledon 2-2 Hartlepool United | Sky Bet League Two |
| 34 | Tue 21 Feb 2023 | 30-1 v Newport CountyHartlepool United 0-1 Newport County | Sky Bet League Two |
| 35 | Sat 25 Feb 2023 | 33-3 v WalsallHartlepool United 3-3 Walsall | Sky Bet League Two |
| 36 | Sat 4 Mar 2023 | 31-1 v Tranmere RoversTranmere Rovers 1-1 Hartlepool United | Sky Bet League Two |
| 37 | Sat 11 Mar 2023 | 31-1 v Northampton TownHartlepool United 1-1 Northampton Town | Sky Bet League Two |
| 38 | Sat 18 Mar 2023 | 32-2 v Bradford CityBradford City 2-2 Hartlepool United | Sky Bet League Two |
| 39 | Sat 25 Mar 2023 | 31-1 v Leyton OrientHartlepool United 1-1 Leyton Orient | Sky Bet League Two |
| 40 | Sat 1 Apr 2023 | 32-1 v Swindon TownHartlepool United 2-1 Swindon Town | Sky Bet League Two |
| 41 | Fri 7 Apr 2023 | 34-1 v Grimsby TownGrimsby Town 1-4 Hartlepool United | Sky Bet League Two |
| 42 | Mon 10 Apr 2023 | 31-1 v StevenageHartlepool United 1-1 Stevenage | Sky Bet League Two |
| 43 | Sat 15 Apr 2023 | 30-2 v Newport CountyNewport County 2-0 Hartlepool United | Sky Bet League Two |
| 44 | Tue 18 Apr 2023 | 30-2 v Salford CitySalford City 2-0 Hartlepool United | Sky Bet League Two |
| 45 | Sat 22 Apr 2023 | 30-2 v Crawley TownHartlepool United 0-2 Crawley Town | Sky Bet League Two |
| 46 | Sat 29 Apr 2023 | 33-1 v BarrowHartlepool United 3-1 Barrow | Sky Bet League Two |
| 47 | Mon 8 May 2023 | 3 1-1 v Stockport CountyStockport County 1-1 Hartlepool United | Sky Bet League Two |
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