| 1 | Tue 4 Oct 2022 | 82-1 v South ShieldsFC United of Manchester 2-1 South Shields | Northern Premier League - Premier Division |
| 2 | Sat 8 Oct 2022 | 140-1 v LiversedgeFC United of Manchester 0-1 Liversedge | Isuzu FA Trophy Third Qualifying Round |
| 3 | Tue 11 Oct 2022 | 84-2 v Morpeth TownFC United of Manchester 4-2 Morpeth Town | Northern Premier League - Premier Division |
| 4 | Sat 15 Oct 2022 | 82-0 v Marske UnitedMarske United 0-2 FC United of Manchester | Northern Premier League - Premier Division |
| 5 | Tue 18 Oct 2022 | 8 1-2 v GuiseleyGuiseley 2-1 FC United of Manchester | Northern Premier League - Premier Division |
| 6 | Sat 22 Oct 2022 | 81-1 v Lancaster CityFC United of Manchester 1-1 Lancaster City | Northern Premier League - Premier Division |
| 7 | Sat 29 Oct 2022 | 84-1 v Stalybridge CelticFC United of Manchester 4-1 Stalybridge Celtic | Manchester Premier Cup First Round |
| 8 | Sat 5 Nov 2022 | 8 2-1 v Stalybridge CelticStalybridge Celtic 1-2 FC United of Manchester | Northern Premier League - Premier Division |
| 9 | Sat 12 Nov 2022 | 82-2 v Warrington RylandsFC United of Manchester 2-2 Warrington Rylands | Northern Premier League - Premier Division |
| 10 | Tue 15 Nov 2022 | 144-1 v KSV BeverenFC United of Manchester 4-1 KSV Beveren | Friendly |
| 11 | Sat 19 Nov 2022 | 141-3 v Gainsborough TrinityFC United of Manchester 1-3 Gainsborough Trinity | Northern Premier League - Premier Division |
| 12 | Sat 26 Nov 2022 | 8 0-1 v Stafford RangersStafford Rangers 1-0 FC United of Manchester | Northern Premier League - Premier Division |
| 13 | Sat 3 Dec 2022 | 82-0 v Belper TownFC United of Manchester 2-0 Belper Town | Northern Premier League - Premier Division |
| 14 | Mon 26 Dec 2022 | 84-0 v Ashton UnitedFC United of Manchester 4-0 Ashton United | Northern Premier League - Premier Division |
| 15 | Mon 2 Jan 2023 | 80-1 v RadcliffeRadcliffe 1-0 FC United of Manchester | Northern Premier League - Premier Division |
| 16 | Sat 7 Jan 2023 | 82-2 v Whitby TownFC United of Manchester 2-2 Whitby Town | Northern Premier League - Premier Division |
| 17 | Sat 14 Jan 2023 | 8 4-4 v Hyde UnitedFC United of Manchester 4-4 Hyde United | Northern Premier League - Premier Division |
| 18 | Tue 24 Jan 2023 | 82-0 v Nantwich TownNantwich Town 0-2 FC United of Manchester | Northern Premier League - Premier Division |
| 19 | Sat 28 Jan 2023 | 8 1-1 v Warrington TownFC United of Manchester 1-1 Warrington Town | Northern Premier League - Premier Division |
| 20 | Sat 4 Feb 2023 | 80-1 v Matlock TownMatlock Town 1-0 FC United of Manchester | Northern Premier League - Premier Division |
| 21 | Tue 14 Mar 2023 | 162-1 v South ShieldsSouth Shields 1-2 FC United of Manchester | Northern Premier League - Premier Division |
| 22 | Sat 18 Mar 2023 | 80-3 v MarineMarine 3-0 FC United of Manchester | Northern Premier League - Premier Division |
| 23 | Sat 25 Mar 2023 | 82-1 v Marske UnitedFC United of Manchester 2-1 Marske United | Northern Premier League - Premier Division |
| 24 | Sat 1 Apr 2023 | 81-0 v Morpeth TownMorpeth Town 0-1 FC United of Manchester | Northern Premier League - Premier Division |
| 25 | Sat 8 Apr 2023 | 85-2 v Bamber BridgeFC United of Manchester 5-2 Bamber Bridge | Northern Premier League - Premier Division |
| 26 | Sat 22 Apr 2023 | 82-1 v Gainsborough TrinityGainsborough Trinity 1-2 FC United of Manchester | Northern Premier League - Premier Division |
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