| 1 | Fri 5 Aug 2022 | 4 2-0 v Crystal PalaceCrystal Palace 0-2 Arsenal | Premier League |
| 2 | Sat 13 Aug 2022 | 44-2 v Leicester CityArsenal 4-2 Leicester City | Premier League |
| 3 | Sat 20 Aug 2022 | 43-0 v AFC BournemouthAFC Bournemouth 0-3 Arsenal | Premier League |
| 4 | Sat 27 Aug 2022 | 4 2-1 v FulhamArsenal 2-1 Fulham | Premier League |
| 5 | Wed 31 Aug 2022 | 42-1 v Aston VillaArsenal 2-1 Aston Villa | Premier League |
| 6 | Sun 4 Sep 2022 | 41-3 v Manchester UnitedManchester United 3-1 Arsenal | Premier League |
| 7 | Sun 18 Sep 2022 | 43-0 v BrentfordBrentford 0-3 Arsenal | Premier League |
| 8 | Sat 1 Oct 2022 | 43-1 v Tottenham HotspurArsenal 3-1 Tottenham Hotspur | Premier League |
| 9 | Sun 9 Oct 2022 | 43-2 v LiverpoolArsenal 3-2 Liverpool | Premier League |
| 10 | Sun 16 Oct 2022 | 41-0 v Leeds UnitedLeeds United 0-1 Arsenal | Premier League |
| 11 | Thu 20 Oct 2022 | 41-0 v PSV EindhovenArsenal 1-0 PSV Eindhoven | UEFA Europa League Group A |
| 12 | Sun 23 Oct 2022 | 41-1 v SouthamptonSouthampton 1-1 Arsenal | Premier League |
| 13 | Thu 27 Oct 2022 | 40-2 v PSV EindhovenPSV Eindhoven 2-0 Arsenal | UEFA Europa League Group A |
| 14 | Sun 30 Oct 2022 | 45-0 v Nottingham ForestArsenal 5-0 Nottingham Forest | Premier League |
| 15 | Thu 3 Nov 2022 | 41-0 v FC ZurichArsenal 1-0 FC Zurich | UEFA Europa League Group A |
| 16 | Sun 6 Nov 2022 | 4 1-0 v ChelseaChelsea 0-1 Arsenal | Premier League |
| 17 | Sat 12 Nov 2022 | 42-0 v Wolverhampton WanderersWolverhampton Wanderers 0-2 Arsenal | Premier League |
| 18 | Mon 26 Dec 2022 | 43-1 v West Ham UnitedArsenal 3-1 West Ham United | Premier League |
| 19 | Sat 31 Dec 2022 | 44-2 v Brighton & Hove AlbionBrighton & Hove Albion 2-4 Arsenal | Premier League |
| 20 | Tue 3 Jan 2023 | 40-0 v Newcastle UnitedArsenal 0-0 Newcastle United | Premier League |
| 21 | Mon 9 Jan 2023 | 43-0 v Oxford UnitedOxford United 0-3 Arsenal | Emirates FA Cup Third Round |
| 22 | Sun 15 Jan 2023 | 42-0 v Tottenham HotspurTottenham Hotspur 0-2 Arsenal | Premier League |
| 23 | Sun 22 Jan 2023 | 4 3-2 v Manchester UnitedArsenal 3-2 Manchester United | Premier League |
| 24 | Sat 4 Feb 2023 | 40-1 v EvertonEverton 1-0 Arsenal | Premier League |
| 25 | Sat 11 Feb 2023 | 41-1 v BrentfordArsenal 1-1 Brentford | Premier League |
| 26 | Wed 15 Feb 2023 | 41-3 v Manchester CityArsenal 1-3 Manchester City | Premier League |
| 27 | Sat 18 Feb 2023 | 44-2 v Aston VillaAston Villa 2-4 Arsenal | Premier League |
| 28 | Sat 25 Feb 2023 | 41-0 v Leicester CityLeicester City 0-1 Arsenal | Premier League |
| 29 | Wed 1 Mar 2023 | 44-0 v EvertonArsenal 4-0 Everton | Premier League |
| 30 | Sat 4 Mar 2023 | 43-2 v AFC BournemouthArsenal 3-2 AFC Bournemouth | Premier League |
| 31 | Thu 9 Mar 2023 | 42-2 v Sporting LisbonSporting Lisbon 2-2 Arsenal | UEFA Europa League Round of 16 |
| 32 | Sun 12 Mar 2023 | 43-0 v FulhamFulham 0-3 Arsenal | Premier League |
| 33 | Thu 16 Mar 2023 | 41-1 v Sporting LisbonArsenal 1-1 Sporting Lisbon | UEFA Europa League Round of 16 |
| 34 | Sun 19 Mar 2023 | 44-1 v Crystal PalaceArsenal 4-1 Crystal Palace | Premier League |
| 35 | Sat 1 Apr 2023 | 44-1 v Leeds UnitedArsenal 4-1 Leeds United | Premier League |
| 36 | Sun 9 Apr 2023 | 4 2-2 v LiverpoolLiverpool 2-2 Arsenal | Premier League |
| 37 | Sun 16 Apr 2023 | 42-2 v West Ham UnitedWest Ham United 2-2 Arsenal | Premier League |
| 38 | Fri 21 Apr 2023 | 43-3 v SouthamptonArsenal 3-3 Southampton | Premier League |
| 39 | Wed 26 Apr 2023 | 41-4 v Manchester CityManchester City 4-1 Arsenal | Premier League |
| 40 | Tue 2 May 2023 | 43-1 v ChelseaArsenal 3-1 Chelsea | Premier League |
| 41 | Sun 7 May 2023 | 42-0 v Newcastle UnitedNewcastle United 0-2 Arsenal | Premier League |
| 42 | Sun 14 May 2023 | 40-3 v Brighton & Hove AlbionArsenal 0-3 Brighton & Hove Albion | Premier League |
| 43 | Sat 20 May 2023 | 40-1 v Nottingham ForestNottingham Forest 1-0 Arsenal | Premier League |
| 44 | Sun 28 May 2023 | 45-0 v Wolverhampton WanderersArsenal 5-0 Wolverhampton Wanderers | Premier League |
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