| 1 | Sun 7 Aug 2022 | 12-2 v Leicester CityLeicester City 2-2 Brentford | Premier League |
| 2 | Sat 13 Aug 2022 | 14-0 v Manchester UnitedBrentford 4-0 Manchester United | Premier League |
| 3 | Sat 20 Aug 2022 | 12-3 v FulhamFulham 3-2 Brentford | Premier League |
| 4 | Sat 27 Aug 2022 | 11-1 v EvertonBrentford 1-1 Everton | Premier League |
| 5 | Tue 30 Aug 2022 | 11-1 v Crystal PalaceCrystal Palace 1-1 Brentford | Premier League |
| 6 | Sat 3 Sep 2022 | 15-2 v Leeds UnitedBrentford 5-2 Leeds United | Premier League |
| 7 | Sun 18 Sep 2022 | 10-3 v ArsenalBrentford 0-3 Arsenal | Premier League |
| 8 | Sat 1 Oct 2022 | 10-0 v AFC BournemouthAFC Bournemouth 0-0 Brentford | Premier League |
| 9 | Sat 8 Oct 2022 | 11-5 v Newcastle UnitedNewcastle United 5-1 Brentford | Premier League |
| 10 | Fri 14 Oct 2022 | 12-0 v Brighton & Hove AlbionBrentford 2-0 Brighton & Hove Albion | Premier League |
| 11 | Wed 19 Oct 2022 | 10-0 v ChelseaBrentford 0-0 Chelsea | Premier League |
| 12 | Sun 23 Oct 2022 | 10-4 v Aston VillaAston Villa 4-0 Brentford | Premier League |
| 13 | Sat 29 Oct 2022 | 11-1 v Wolverhampton WanderersBrentford 1-1 Wolverhampton Wanderers | Premier League |
| 14 | Sat 5 Nov 2022 | 12-2 v Nottingham ForestNottingham Forest 2-2 Brentford | Premier League |
| 15 | Tue 8 Nov 2022 | 11-1 v GillinghamBrentford 1-1 Gillingham | Carabao Cup Third Round |
| 16 | Sat 12 Nov 2022 | 12-1 v Manchester CityManchester City 1-2 Brentford | Premier League |
| 17 | Thu 17 Nov 2022 | 133-1 v JordanJordan 1-3 Spain | International Friendly |
| 18 | Mon 26 Dec 2022 | 12-2 v Tottenham HotspurBrentford 2-2 Tottenham Hotspur | Premier League |
| 19 | Fri 30 Dec 2022 | 12-0 v West Ham UnitedWest Ham United 0-2 Brentford | Premier League |
| 20 | Mon 2 Jan 2023 | 13-1 v LiverpoolBrentford 3-1 Liverpool | Premier League |
| 21 | Sat 14 Jan 2023 | 1 2-0 v AFC BournemouthBrentford 2-0 AFC Bournemouth | Premier League |
| 22 | Sun 22 Jan 2023 | 10-0 v Leeds UnitedLeeds United 0-0 Brentford | Premier League |
| 23 | Sat 4 Feb 2023 | 13-0 v SouthamptonBrentford 3-0 Southampton | Premier League |
| 24 | Sat 11 Feb 2023 | 11-1 v ArsenalArsenal 1-1 Brentford | Premier League |
| 25 | Sat 18 Feb 2023 | 11-1 v Crystal PalaceBrentford 1-1 Crystal Palace | Premier League |
| 26 | Mon 6 Mar 2023 | 13-2 v FulhamBrentford 3-2 Fulham | Premier League |
| 27 | Sat 11 Mar 2023 | 10-1 v EvertonEverton 1-0 Brentford | Premier League |
| 28 | Wed 15 Mar 2023 | 12-0 v SouthamptonSouthampton 0-2 Brentford | Premier League |
| 29 | Sat 18 Mar 2023 | 11-1 v Leicester CityBrentford 1-1 Leicester City | Premier League |
| 30 | Sat 1 Apr 2023 | 13-3 v Brighton & Hove AlbionBrighton & Hove Albion 3-3 Brentford | Premier League |
| 31 | Wed 5 Apr 2023 | 10-1 v Manchester UnitedManchester United 1-0 Brentford | Premier League |
| 32 | Sat 8 Apr 2023 | 11-2 v Newcastle UnitedBrentford 1-2 Newcastle United | Premier League |
| 33 | Sat 15 Apr 2023 | 10-2 v Wolverhampton WanderersWolverhampton Wanderers 2-0 Brentford | Premier League |
| 34 | Sat 22 Apr 2023 | 11-1 v Aston VillaBrentford 1-1 Aston Villa | Premier League |
| 35 | Wed 26 Apr 2023 | 12-0 v ChelseaChelsea 0-2 Brentford | Premier League |
| 36 | Sat 29 Apr 2023 | 12-1 v Nottingham ForestBrentford 2-1 Nottingham Forest | Premier League |
| 37 | Sat 6 May 2023 | 10-1 v LiverpoolLiverpool 1-0 Brentford | Premier League |
| 38 | Sun 14 May 2023 | 12-0 v West Ham UnitedBrentford 2-0 West Ham United | Premier League |
| 39 | Sat 20 May 2023 | 13-1 v Tottenham HotspurTottenham Hotspur 1-3 Brentford | Premier League |
| 40 | Sun 28 May 2023 | 11-0 v Manchester CityBrentford 1-0 Manchester City | Premier League |
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