| 1 | Sat 1 Oct 2022 | 41-3 v ArsenalArsenal 3-1 Tottenham Hotspur | Premier League |
| 2 | Sat 8 Oct 2022 | 41-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-1 Tottenham Hotspur | Premier League |
| 3 | Wed 12 Oct 2022 | 43-2 v Eintracht FrankfurtTottenham Hotspur 3-2 Eintracht Frankfurt | UEFA Champions League Group D |
| 4 | Sat 15 Oct 2022 | 42-0 v EvertonTottenham Hotspur 2-0 Everton | Premier League |
| 5 | Wed 19 Oct 2022 | 40-2 v Manchester UnitedManchester United 2-0 Tottenham Hotspur | Premier League |
| 6 | Sun 23 Oct 2022 | 4 1-2 v Newcastle UnitedTottenham Hotspur 1-2 Newcastle United | Premier League |
| 7 | Sat 29 Oct 2022 | 43-2 v AFC BournemouthAFC Bournemouth 2-3 Tottenham Hotspur | Premier League |
| 8 | Tue 1 Nov 2022 | 42-1 v MarseilleMarseille 1-2 Tottenham Hotspur | UEFA Champions League Group D |
| 9 | Wed 9 Nov 2022 | 40-2 v Nottingham ForestNottingham Forest 2-0 Tottenham Hotspur | Carabao Cup Third Round |
| 10 | Sun 1 Jan 2023 | 40-2 v Aston VillaTottenham Hotspur 0-2 Aston Villa | Premier League |
| 11 | Wed 4 Jan 2023 | 4 4-0 v Crystal PalaceCrystal Palace 0-4 Tottenham Hotspur | Premier League |
| 12 | Sat 28 Jan 2023 | 43-0 v Preston North EndPreston North End 0-3 Tottenham Hotspur | Emirates FA Cup Fourth Round |
| 13 | Tue 14 Feb 2023 | 40-1 v AC MilanAC Milan 1-0 Tottenham Hotspur | UEFA Champions League Round of 16 |
| 14 | Sun 19 Feb 2023 | 4 2-0 v West Ham UnitedTottenham Hotspur 2-0 West Ham United | Premier League |
| 15 | Sun 26 Feb 2023 | 42-0 v ChelseaTottenham Hotspur 2-0 Chelsea | Premier League |
| 16 | Wed 1 Mar 2023 | 40-1 v Sheffield UnitedSheffield United 1-0 Tottenham Hotspur | Emirates FA Cup Fifth Round |
| 17 | Sat 4 Mar 2023 | 40-1 v Wolverhampton WanderersWolverhampton Wanderers 1-0 Tottenham Hotspur | Premier League |
| 18 | Wed 8 Mar 2023 | 4 0-0 v AC MilanTottenham Hotspur 0-0 AC Milan | UEFA Champions League Round of 16 |
| 19 | Sat 11 Mar 2023 | 4 3-1 v Nottingham ForestTottenham Hotspur 3-1 Nottingham Forest | Premier League |
| 20 | Sat 18 Mar 2023 | 4 3-3 v SouthamptonSouthampton 3-3 Tottenham Hotspur | Premier League |
| 21 | Mon 3 Apr 2023 | 41-1 v EvertonEverton 1-1 Tottenham Hotspur | Premier League |
| 22 | Sat 8 Apr 2023 | 42-1 v Brighton & Hove AlbionTottenham Hotspur 2-1 Brighton & Hove Albion | Premier League |
| 23 | Sat 15 Apr 2023 | 42-3 v AFC BournemouthTottenham Hotspur 2-3 AFC Bournemouth | Premier League |
| 24 | Sun 23 Apr 2023 | 4 1-6 v Newcastle UnitedNewcastle United 6-1 Tottenham Hotspur | Premier League |
| 25 | Thu 27 Apr 2023 | 42-2 v Manchester UnitedTottenham Hotspur 2-2 Manchester United | Premier League |
| 26 | Sun 30 Apr 2023 | 43-4 v LiverpoolLiverpool 4-3 Tottenham Hotspur | Premier League |
| 27 | Sat 6 May 2023 | 41-0 v Crystal PalaceTottenham Hotspur 1-0 Crystal Palace | Premier League |
| 28 | Sat 13 May 2023 | 4 1-2 v Aston VillaAston Villa 2-1 Tottenham Hotspur | Premier League |
| 29 | Sat 20 May 2023 | 41-3 v BrentfordTottenham Hotspur 1-3 Brentford | Premier League |
| 30 | Sun 28 May 2023 | 44-1 v Leeds UnitedLeeds United 1-4 Tottenham Hotspur | Premier League |
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