| 1 | Sun 7 Aug 2022 | 30-2 v Manchester CityWest Ham United 0-2 Manchester City | Premier League |
| 2 | Sun 14 Aug 2022 | 30-1 v Nottingham ForestNottingham Forest 1-0 West Ham United | Premier League |
| 3 | Sun 21 Aug 2022 | 3 0-2 v Brighton & Hove AlbionWest Ham United 0-2 Brighton & Hove Albion | Premier League |
| 4 | Thu 25 Aug 2022 | 3 3-0 v ViborgViborg 0-3 West Ham United | UEFA Europa Conference League Play-off |
| 5 | Sun 28 Aug 2022 | 31-0 v Aston VillaAston Villa 0-1 West Ham United | Premier League |
| 6 | Wed 31 Aug 2022 | 31-1 v Tottenham HotspurWest Ham United 1-1 Tottenham Hotspur | Premier League |
| 7 | Thu 15 Sep 2022 | 3 3-2 v Silkeborg IFSilkeborg IF 2-3 West Ham United | UEFA Europa Conference League Group B |
| 8 | Sun 18 Sep 2022 | 30-1 v EvertonEverton 1-0 West Ham United | Premier League |
| 9 | Sat 1 Oct 2022 | 3 2-0 v Wolverhampton WanderersWest Ham United 2-0 Wolverhampton Wanderers | Premier League |
| 10 | Sun 9 Oct 2022 | 33-1 v FulhamWest Ham United 3-1 Fulham | Premier League |
| 11 | Thu 13 Oct 2022 | 32-1 v RSC AnderlechtWest Ham United 2-1 RSC Anderlecht | UEFA Europa Conference League Group B |
| 12 | Sun 16 Oct 2022 | 31-1 v SouthamptonSouthampton 1-1 West Ham United | Premier League |
| 13 | Wed 19 Oct 2022 | 30-1 v LiverpoolLiverpool 1-0 West Ham United | Premier League |
| 14 | Mon 24 Oct 2022 | 32-0 v AFC BournemouthWest Ham United 2-0 AFC Bournemouth | Premier League |
| 15 | Sun 30 Oct 2022 | 30-1 v Manchester UnitedManchester United 1-0 West Ham United | Premier League |
| 16 | Sun 6 Nov 2022 | 31-2 v Crystal PalaceWest Ham United 1-2 Crystal Palace | Premier League |
| 17 | Wed 9 Nov 2022 | 32-2 v Blackburn RoversWest Ham United 2-2 Blackburn Rovers | Carabao Cup Third Round |
| 18 | Sat 12 Nov 2022 | 30-2 v Leicester CityWest Ham United 0-2 Leicester City | Premier League |
| 19 | Mon 26 Dec 2022 | 31-3 v ArsenalArsenal 3-1 West Ham United | Premier League |
| 20 | Fri 30 Dec 2022 | 30-2 v BrentfordWest Ham United 0-2 Brentford | Premier League |
| 21 | Wed 4 Jan 2023 | 32-2 v Leeds UnitedLeeds United 2-2 West Ham United | Premier League |
| 22 | Sat 14 Jan 2023 | 30-1 v Wolverhampton WanderersWolverhampton Wanderers 1-0 West Ham United | Premier League |
| 23 | Mon 30 Jan 2023 | 32-0 v Derby CountyDerby County 0-2 West Ham United | Emirates FA Cup Fourth Round |
| 24 | Sat 25 Feb 2023 | 34-0 v Nottingham ForestWest Ham United 4-0 Nottingham Forest | Premier League |
| 25 | Thu 9 Mar 2023 | 32-0 v AEK LarnacaAEK Larnaca 0-2 West Ham United | UEFA Europa Conference League Round of 16 |
| 26 | Thu 16 Mar 2023 | 34-0 v AEK LarnacaWest Ham United 4-0 AEK Larnaca | UEFA Europa Conference League Round of 16 |
| 27 | Sun 2 Apr 2023 | 31-0 v SouthamptonWest Ham United 1-0 Southampton | Premier League |
| 28 | Sat 8 Apr 2023 | 31-0 v FulhamFulham 0-1 West Ham United | Premier League |
| 29 | Thu 13 Apr 2023 | 31-1 v KAA GentKAA Gent 1-1 West Ham United | UEFA Europa Conference League Quarter Final |
| 30 | Sun 16 Apr 2023 | 3 2-2 v ArsenalWest Ham United 2-2 Arsenal | Premier League |
| 31 | Sun 23 Apr 2023 | 34-0 v AFC BournemouthAFC Bournemouth 0-4 West Ham United | Premier League |
| 32 | Wed 26 Apr 2023 | 31-2 v LiverpoolWest Ham United 1-2 Liverpool | Premier League |
| 33 | Sat 29 Apr 2023 | 33-4 v Crystal PalaceCrystal Palace 4-3 West Ham United | Premier League |
| 34 | Wed 3 May 2023 | 30-3 v Manchester CityManchester City 3-0 West Ham United | Premier League |
| 35 | Sun 7 May 2023 | 31-0 v Manchester UnitedWest Ham United 1-0 Manchester United | Premier League |
| 36 | Thu 11 May 2023 | 32-1 v AZ AlkmaarWest Ham United 2-1 AZ Alkmaar | UEFA Europa Conference League Semi Final |
| 37 | Thu 18 May 2023 | 31-0 v AZ AlkmaarAZ Alkmaar 0-1 West Ham United | UEFA Europa Conference League Semi Final |
| 38 | Sun 28 May 2023 | 31-2 v Leicester CityLeicester City 2-1 West Ham United | Premier League |
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