| 1 | Sat 19 Aug | 223-1 v FrosinoneFrosinone 1-3 Napoli | Italian Serie A |
| 2 | Sun 27 Aug | 222-0 v SassuoloNapoli 2-0 Sassuolo | Italian Serie A |
| 3 | Sat 2 Sep | 221-2 v LazioNapoli 1-2 Lazio | Italian Serie A |
| 4 | Sat 16 Sep | 222-2 v GenoaGenoa 2-2 Napoli | Italian Serie A |
| 5 | Wed 20 Sep | 222-1 v Sporting BragaSporting Braga 1-2 Napoli | UEFA Champions League Group C |
| 6 | Sun 24 Sep | 220-0 v BolognaBologna 0-0 Napoli | Italian Serie A |
| 7 | Wed 27 Sep | 224-1 v UdineseNapoli 4-1 Udinese | Italian Serie A |
| 8 | Sat 30 Sep | 224-0 v LecceLecce 0-4 Napoli | Italian Serie A |
| 9 | Tue 3 Oct | 222-3 v Real MadridNapoli 2-3 Real Madrid | UEFA Champions League Group C |
| 10 | Sun 8 Oct | 221-3 v FiorentinaNapoli 1-3 Fiorentina | Italian Serie A |
| 11 | Sat 21 Oct | 223-1 v Hellas VeronaHellas Verona 1-3 Napoli | Italian Serie A |
| 12 | Tue 24 Oct | 221-0 v 1 FC Union Berlin1 FC Union Berlin 0-1 Napoli | UEFA Champions League Group C |
| 13 | Sun 29 Oct | 22 2-2 v AC MilanNapoli 2-2 AC Milan | Italian Serie A |
| 14 | Sat 4 Nov | 22 2-0 v SalernitanaSalernitana 0-2 Napoli | Italian Serie A |
| 15 | Wed 8 Nov | 221-1 v 1 FC Union BerlinNapoli 1-1 1 FC Union Berlin | UEFA Champions League Group C |
| 16 | Sun 12 Nov | 220-1 v EmpoliNapoli 0-1 Empoli | Italian Serie A |
| 17 | Sat 25 Nov | 22 2-1 v AtalantaAtalanta 1-2 Napoli | Italian Serie A |
| 18 | Wed 29 Nov | 222-4 v Real MadridReal Madrid 4-2 Napoli | UEFA Champions League Group C |
| 19 | Sun 3 Dec | 220-3 v Inter MilanNapoli 0-3 Inter Milan | Italian Serie A |
| 20 | Fri 8 Dec | 220-1 v JuventusJuventus 1-0 Napoli | Italian Serie A |
| 21 | Tue 12 Dec | 222-0 v Sporting BragaNapoli 2-0 Sporting Braga | UEFA Champions League Group C |
| 22 | Sat 16 Dec | 222-1 v CagliariNapoli 2-1 Cagliari | Italian Serie A |
| 23 | Sat 23 Dec | 220-2 v RomaRoma 2-0 Napoli | Italian Serie A |
| 24 | Fri 29 Dec | 22 0-0 v MonzaNapoli 0-0 Monza | Italian Serie A |
| 25 | Sun 7 Jan | 220-3 v TorinoTorino 3-0 Napoli | Italian Serie A |
| 26 | Sat 13 Jan | 222-1 v SalernitanaNapoli 2-1 Salernitana | Italian Serie A |
| 27 | Sun 28 Jan | 220-0 v LazioLazio 0-0 Napoli | Italian Serie A |
| 28 | Sun 4 Feb | 222-1 v Hellas VeronaNapoli 2-1 Hellas Verona | Italian Serie A |
| 29 | Sun 11 Feb | 220-1 v AC MilanAC Milan 1-0 Napoli | Italian Serie A |
| 30 | Sat 17 Feb | 22 1-1 v GenoaNapoli 1-1 Genoa | Italian Serie A |
| 31 | Wed 21 Feb | 221-1 v BarcelonaNapoli 1-1 Barcelona | UEFA Champions League Round of 16 |
| 32 | Wed 28 Feb | 226-1 v SassuoloSassuolo 1-6 Napoli | Italian Serie A |
| 33 | Sun 3 Mar | 222-1 v JuventusNapoli 2-1 Juventus | Italian Serie A |
| 34 | Fri 8 Mar | 221-1 v TorinoNapoli 1-1 Torino | Italian Serie A |
| 35 | Tue 12 Mar | 221-3 v BarcelonaBarcelona 3-1 Napoli | UEFA Champions League Round of 16 |
| 36 | Sun 17 Mar | 221-1 v Inter MilanInter Milan 1-1 Napoli | Italian Serie A |
| 37 | Sat 30 Mar | 22 0-3 v AtalantaNapoli 0-3 Atalanta | Italian Serie A |
| 38 | Sun 7 Apr | 224-2 v MonzaMonza 2-4 Napoli | Italian Serie A |
| 39 | Sun 14 Apr | 222-2 v FrosinoneNapoli 2-2 Frosinone | Italian Serie A |
| 40 | Sat 20 Apr | 220-1 v EmpoliEmpoli 1-0 Napoli | Italian Serie A |
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