| 1 | Tue 4 Aug | 81-2 v Sparta PragueSparta Prague 2-1 Olympique Lyonnais | UEFA Champions League Third Qualifying Round |
| 2 | Tue 11 Aug | 83-0 v Sparta PragueOlympique Lyonnais 3-0 Sparta Prague | UEFA Champions League Third Qualifying Round |
| 3 | Tue 18 Aug | 81-1 v FenerbahçeFenerbahçe 1-1 Olympique Lyonnais | UEFA Champions League Play-off |
| 4 | Sat 22 Aug | 82-0 v ToulouseToulouse 0-2 Olympique Lyonnais | French Ligue 1 |
| 5 | Wed 26 Aug | 81-2 v FenerbahçeOlympique Lyonnais 1-2 Fenerbahçe | UEFA Champions League Play-off |
| 6 | Sat 29 Aug | 81-1 v Le HavreOlympique Lyonnais 1-1 Le Havre | French Ligue 1 |
| 7 | Fri 4 Sep | 83-1 v AuxerreOlympique Lyonnais 3-1 Auxerre | French Ligue 1 |
| 8 | Sat 12 Sep | 80-0 v Paris FCParis FC 0-0 Olympique Lyonnais | French Ligue 1 |
| 9 | Wed 16 Sep | 82-1 v RSC AnderlechtRSC Anderlecht 1-2 Olympique Lyonnais | UEFA Europa League Matchday 1 |
| 10 | Sat 19 Sep | 84-0 v RennesOlympique Lyonnais 4-0 Rennes | French Ligue 1 |
| 11 | Fri 9 Oct | 81-2 v LensLens 2-1 Olympique Lyonnais | French Ligue 1 |
| 12 | Thu 15 Oct | 83-2 v Crystal PalaceOlympique Lyonnais 3-2 Crystal Palace | UEFA Europa League Matchday 2 |
| 13 | Sun 18 Oct | 82-1 v NiceOlympique Lyonnais 2-1 Nice | French Ligue 1 |
| 14 | Thu 22 Oct | 80-3 v TSG HoffenheimTSG Hoffenheim 3-0 Olympique Lyonnais | UEFA Europa League Matchday 3 |
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