| 1 | Tue 18 Aug | 21-1 v FenerbahçeFenerbahçe 1-1 Olympique Lyonnais | UEFA Champions League Play-off |
| 2 | Sat 22 Aug | 22-0 v ToulouseToulouse 0-2 Olympique Lyonnais | French Ligue 1 |
| 3 | Wed 26 Aug | 21-2 v FenerbahçeOlympique Lyonnais 1-2 Fenerbahçe | UEFA Champions League Play-off |
| 4 | Sat 29 Aug | 21-1 v Le HavreOlympique Lyonnais 1-1 Le Havre | French Ligue 1 |
| 5 | Fri 4 Sep | 23-1 v AuxerreOlympique Lyonnais 3-1 Auxerre | French Ligue 1 |
| 6 | Sat 12 Sep | 20-0 v Paris FCParis FC 0-0 Olympique Lyonnais | French Ligue 1 |
| 7 | Wed 16 Sep | 22-1 v RSC AnderlechtRSC Anderlecht 1-2 Olympique Lyonnais | UEFA Europa League Matchday 1 |
| 8 | Sat 19 Sep | 24-0 v RennesOlympique Lyonnais 4-0 Rennes | French Ligue 1 |
| 9 | Fri 9 Oct | 21-2 v LensLens 2-1 Olympique Lyonnais | French Ligue 1 |
| 10 | Thu 15 Oct | 23-2 v Crystal PalaceOlympique Lyonnais 3-2 Crystal Palace | UEFA Europa League Matchday 2 |
| 11 | Sun 18 Oct | 22-1 v NiceOlympique Lyonnais 2-1 Nice | French Ligue 1 |
| 12 | Thu 22 Oct | 20-3 v TSG HoffenheimTSG Hoffenheim 3-0 Olympique Lyonnais | UEFA Europa League Matchday 3 |
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