| 1 | Sat 14 Aug 2021 | 50-0 v EspanyolOsasuna 0-0 Espanyol | Spanish La Liga |
| 2 | Mon 23 Aug 2021 | 50-0 v Celta VigoOsasuna 0-0 Celta Vigo | Spanish La Liga |
| 3 | Sun 29 Aug 2021 | 53-2 v CádizCádiz 2-3 Osasuna | Spanish La Liga |
| 4 | Sun 12 Sep 2021 | 5 1-4 v ValenciaOsasuna 1-4 Valencia | Spanish La Liga |
| 5 | Sat 18 Sep 2021 | 52-0 v AlavésAlavés 0-2 Osasuna | Spanish La Liga |
| 6 | Thu 23 Sep 2021 | 5 1-3 v Real BetisOsasuna 1-3 Real Betis | Spanish La Liga |
| 7 | Sun 26 Sep 2021 | 53-2 v MallorcaMallorca 2-3 Osasuna | Spanish La Liga |
| 8 | Sat 2 Oct 2021 | 51-0 v Rayo VallecanoOsasuna 1-0 Rayo Vallecano | Spanish La Liga |
| 9 | Sun 17 Oct 2021 | 5 2-1 v VillarrealVillarreal 1-2 Osasuna | Spanish La Liga |
| 10 | Fri 22 Oct 2021 | 51-1 v GranadaOsasuna 1-1 Granada | Spanish La Liga |
| 11 | Wed 27 Oct 2021 | 50-0 v Real MadridReal Madrid 0-0 Osasuna | Spanish La Liga |
| 12 | Sat 30 Oct 2021 | 50-2 v SevillaSevilla 2-0 Osasuna | Spanish La Liga |
| 13 | Sun 7 Nov 2021 | 50-2 v Real SociedadOsasuna 0-2 Real Sociedad | Spanish La Liga |
| 14 | Sat 20 Nov 2021 | 5 0-1 v Atlético MadridAtlético Madrid 1-0 Osasuna | Spanish La Liga |
| 15 | Mon 29 Nov 2021 | 51-1 v ElcheOsasuna 1-1 Elche | Spanish La Liga |
| 16 | Sun 5 Dec 2021 | 50-0 v LevanteLevante 0-0 Osasuna | Spanish La Liga |
| 17 | Sun 12 Dec 2021 | 5 2-2 v BarcelonaOsasuna 2-2 Barcelona | Spanish La Liga |
| 18 | Mon 3 Jan 2022 | 51-3 v Athletic BilbaoOsasuna 1-3 Athletic Bilbao | Spanish La Liga |
| 19 | Sun 9 Jan 2022 | 52-0 v CádizOsasuna 2-0 Cádiz | Spanish La Liga |
| 20 | Sun 23 Jan 2022 | 52-0 v GranadaGranada 0-2 Osasuna | Spanish La Liga |
| 21 | Sat 5 Feb 2022 | 50-0 v SevillaOsasuna 0-0 Sevilla | Spanish La Liga |
| 22 | Sat 12 Feb 2022 | 53-0 v Rayo VallecanoRayo Vallecano 0-3 Osasuna | Spanish La Liga |
| 23 | Sat 19 Feb 2022 | 50-3 v Atlético MadridOsasuna 0-3 Atlético Madrid | Spanish La Liga |
| 24 | Sun 27 Feb 2022 | 50-1 v Real SociedadReal Sociedad 1-0 Osasuna | Spanish La Liga |
| 25 | Sat 5 Mar 2022 | 51-0 v VillarrealOsasuna 1-0 Villarreal | Spanish La Liga |
| 26 | Sun 13 Mar 2022 | 5 0-4 v BarcelonaBarcelona 4-0 Osasuna | Spanish La Liga |
| 27 | Sat 19 Mar 2022 | 53-1 v LevanteOsasuna 3-1 Levante | Spanish La Liga |
| 28 | Sun 3 Apr 2022 | 5 1-4 v Real BetisReal Betis 4-1 Osasuna | Spanish La Liga |
| 29 | Sun 10 Apr 2022 | 51-0 v AlavésOsasuna 1-0 Alavés | Spanish La Liga |
| 30 | Sat 16 Apr 2022 | 52-1 v ValenciaValencia 1-2 Osasuna | Spanish La Liga |
| 31 | Wed 20 Apr 2022 | 51-3 v Real MadridOsasuna 1-3 Real Madrid | Spanish La Liga |
| 32 | Sun 1 May 2022 | 51-1 v ElcheElche 1-1 Osasuna | Spanish La Liga |
| 33 | Sun 8 May 2022 | 51-1 v EspanyolEspanyol 1-1 Osasuna | Spanish La Liga |
| 34 | Wed 11 May 2022 | 51-1 v GetafeOsasuna 1-1 Getafe | Spanish La Liga |
| 35 | Sun 22 May 2022 | 5 0-2 v MallorcaOsasuna 0-2 Mallorca | Spanish La Liga |
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