| 1 | 31/7/2021 | 331-1 v Cercle BruggeCercle Brugge 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 2 | 8/8/2021 | 331-1 v Sporting de CharleroiOud-Heverlee Leuven 1-1 Sporting de Charleroi | Belgian First Division A |
| 3 | 14/8/2021 | 330-4 v KRC GenkKRC Genk 4-0 Oud-Heverlee Leuven | Belgian First Division A |
| 4 | 21/8/2021 | 331-4 v KAS EupenOud-Heverlee Leuven 1-4 KAS Eupen | Belgian First Division A |
| 5 | 29/8/2021 | 33 2-2 v Royal AntwerpRoyal Antwerp 2-2 Oud-Heverlee Leuven | Belgian First Division A |
| 6 | 12/9/2021 | 332-1 v KV KortrijkOud-Heverlee Leuven 2-1 KV Kortrijk | Belgian First Division A |
| 7 | 18/9/2021 | 330-2 v MechelenMechelen 2-0 Oud-Heverlee Leuven | Belgian First Division A |
| 8 | 24/9/2021 | 33 1-1 v Club BruggeClub Brugge 1-1 Oud-Heverlee Leuven | Belgian First Division A |
| 9 | 2/10/2021 | 33 0-0 v Germinal BeerschotOud-Heverlee Leuven 0-0 Germinal Beerschot | Belgian First Division A |
| 10 | 16/10/2021 | 332-2 v Standard LiègeStandard Liège 2-2 Oud-Heverlee Leuven | Belgian First Division A |
| 11 | 24/10/2021 | 334-1 v Sint-Truidense VVOud-Heverlee Leuven 4-1 Sint-Truidense VV | Belgian First Division A |
| 12 | 31/10/2021 | 332-2 v RSC AnderlechtRSC Anderlecht 2-2 Oud-Heverlee Leuven | Belgian First Division A |
| 13 | 5/11/2021 | 331-0 v KV OostendeOud-Heverlee Leuven 1-0 KV Oostende | Belgian First Division A |
| 14 | 4/12/2021 | 330-1 v KAA GentOud-Heverlee Leuven 0-1 KAA Gent | Belgian First Division A |
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