| 1 | Sat 10 Aug | 52-0 v Norwich CityOxford United 2-0 Norwich City | Sky Bet Championship |
| 2 | Tue 13 Aug | 52-0 v Peterborough UnitedOxford United 2-0 Peterborough United | Carabao Cup First Round |
| 3 | Fri 16 Aug | 52-3 v Coventry CityCoventry City 3-2 Oxford United | Sky Bet Championship |
| 4 | Sat 14 Sep | 51-0 v Stoke CityOxford United 1-0 Stoke City | Sky Bet Championship |
| 5 | Sat 21 Sep | 5 1-2 v Bristol CityBristol City 2-1 Oxford United | Sky Bet Championship |
| 6 | Sat 28 Sep | 50-0 v BurnleyOxford United 0-0 Burnley | Sky Bet Championship |
| 7 | Tue 1 Oct | 5 2-2 v Luton TownLuton Town 2-2 Oxford United | Sky Bet Championship |
| 8 | Sat 19 Oct | 51-1 v West Bromwich AlbionOxford United 1-1 West Bromwich Albion | Sky Bet Championship |
| 9 | Tue 22 Oct | 51-1 v Derby CountyOxford United 1-1 Derby County | Sky Bet Championship |
| 10 | Sat 26 Oct | 50-2 v SunderlandSunderland 2-0 Oxford United | Sky Bet Championship |
| 11 | Sat 2 Nov | 51-2 v Swansea CityOxford United 1-2 Swansea City | Sky Bet Championship |
| 12 | Tue 5 Nov | 5 1-0 v Hull CityOxford United 1-0 Hull City | Sky Bet Championship |
| 13 | Fri 8 Nov | 5 0-1 v WatfordWatford 1-0 Oxford United | Sky Bet Championship |
| 14 | Sat 23 Nov | 5 2-6 v MiddlesbroughOxford United 2-6 Middlesbrough | Sky Bet Championship |
| 15 | Sat 30 Nov | 51-1 v MillwallOxford United 1-1 Millwall | Sky Bet Championship |
| 16 | Wed 11 Dec | 5 0-2 v Queens Park RangersQueens Park Rangers 2-0 Oxford United | Sky Bet Championship |
| 17 | Sat 14 Dec | 51-3 v Sheffield WednesdayOxford United 1-3 Sheffield Wednesday | Sky Bet Championship |
| 18 | Sat 21 Dec | 50-4 v Leeds UnitedLeeds United 4-0 Oxford United | Sky Bet Championship |
| 19 | Thu 26 Dec | 53-2 v Cardiff CityOxford United 3-2 Cardiff City | Sky Bet Championship |
| 20 | Sun 29 Dec | 52-0 v Plymouth ArgyleOxford United 2-0 Plymouth Argyle | Sky Bet Championship |
| 21 | Wed 1 Jan | 51-0 v MillwallMillwall 0-1 Oxford United | Sky Bet Championship |
| 22 | Sat 1 Mar | 52-3 v Coventry CityOxford United 2-3 Coventry City | Sky Bet Championship |
| 23 | Fri 7 Mar | 5 1-1 v Norwich CityNorwich City 1-1 Oxford United | Sky Bet Championship |
| 24 | Wed 12 Mar | 51-2 v Hull CityHull City 2-1 Oxford United | Sky Bet Championship |
| 25 | Mon 21 Apr | 51-1 v Cardiff CityCardiff City 1-1 Oxford United | Sky Bet Championship |
| 26 | Sat 26 Apr | 52-0 v SunderlandOxford United 2-0 Sunderland | Sky Bet Championship |
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