| 1 | 20/8/2021 | 54-2 v BrestBrest 2-4 Paris St Germain | French Ligue 1 |
| 2 | 29/8/2021 | 52-0 v ReimsReims 0-2 Paris St Germain | French Ligue 1 |
| 3 | 15/9/2021 | 51-1 v Club BruggeClub Brugge 1-1 Paris St Germain | UEFA Champions League Group A |
| 4 | 19/9/2021 | 5 2-1 v LyonParis St Germain 2-1 Lyon | French Ligue 1 |
| 5 | 22/9/2021 | 52-1 v MetzMetz 1-2 Paris St Germain | French Ligue 1 |
| 6 | 25/9/2021 | 52-0 v MontpellierParis St Germain 2-0 Montpellier | French Ligue 1 |
| 7 | 28/9/2021 | 52-0 v Manchester CityParis St Germain 2-0 Manchester City | UEFA Champions League Group A |
| 8 | 3/10/2021 | 50-2 v RennesRennes 2-0 Paris St Germain | French Ligue 1 |
| 9 | 19/10/2021 | 53-2 v RB LeipzigParis St Germain 3-2 RB Leipzig | UEFA Champions League Group A |
| 10 | 24/10/2021 | 5 0-0 v MarseilleMarseille 0-0 Paris St Germain | French Ligue 1 |
| 11 | 29/10/2021 | 52-1 v LilleParis St Germain 2-1 Lille | French Ligue 1 |
| 12 | 3/11/2021 | 52-2 v RB LeipzigRB Leipzig 2-2 Paris St Germain | UEFA Champions League Group A |
| 13 | 6/11/2021 | 53-2 v BordeauxBordeaux 2-3 Paris St Germain | French Ligue 1 |
| 14 | 24/11/2021 | 51-2 v Manchester CityManchester City 2-1 Paris St Germain | UEFA Champions League Group A |
| 15 | 28/11/2021 | 53-1 v Saint ÉtienneSaint Étienne 1-3 Paris St Germain | French Ligue 1 |
| 16 | 1/12/2021 | 50-0 v NiceParis St Germain 0-0 Nice | French Ligue 1 |
| 17 | 4/12/2021 | 51-1 v LensLens 1-1 Paris St Germain | French Ligue 1 |
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