| 1 | Sun 11 Aug | 20-4 v Sheffield WednesdaySheffield Wednesday 4-0 Plymouth Argyle | Sky Bet Championship |
| 2 | Wed 14 Aug | 23-0 v Cheltenham TownPlymouth Argyle 3-0 Cheltenham Town | Carabao Cup First Round |
| 3 | Sat 17 Aug | 21-1 v Hull CityPlymouth Argyle 1-1 Hull City | Sky Bet Championship |
| 4 | Sat 24 Aug | 21-1 v Queens Park RangersQueens Park Rangers 1-1 Plymouth Argyle | Sky Bet Championship |
| 5 | Sat 31 Aug | 20-1 v Stoke CityPlymouth Argyle 0-1 Stoke City | Sky Bet Championship |
| 6 | Sat 14 Sep | 23-2 v SunderlandPlymouth Argyle 3-2 Sunderland | Sky Bet Championship |
| 7 | Sat 21 Sep | 20-1 v West Bromwich AlbionWest Bromwich Albion 1-0 Plymouth Argyle | Sky Bet Championship |
| 8 | Fri 27 Sep | 23-1 v Luton TownPlymouth Argyle 3-1 Luton Town | Sky Bet Championship |
| 9 | Tue 1 Oct | 20-1 v BurnleyBurnley 1-0 Plymouth Argyle | Sky Bet Championship |
| 10 | Sat 5 Oct | 2 2-1 v Blackburn RoversPlymouth Argyle 2-1 Blackburn Rovers | Sky Bet Championship |
| 11 | Sat 19 Oct | 20-5 v Cardiff CityCardiff City 5-0 Plymouth Argyle | Sky Bet Championship |
| 12 | Wed 23 Oct | 20-1 v MillwallMillwall 1-0 Plymouth Argyle | Sky Bet Championship |
| 13 | Sat 26 Oct | 23-3 v Preston North EndPlymouth Argyle 3-3 Preston North End | Sky Bet Championship |
| 14 | Sat 2 Nov | 20-3 v Leeds UnitedLeeds United 3-0 Plymouth Argyle | Sky Bet Championship |
| 15 | Tue 5 Nov | 21-0 v PortsmouthPlymouth Argyle 1-0 Portsmouth | Sky Bet Championship |
| 16 | Sat 9 Nov | 2 1-1 v Derby CountyDerby County 1-1 Plymouth Argyle | Sky Bet Championship |
| 17 | Fri 22 Nov | 2 2-2 v WatfordPlymouth Argyle 2-2 Watford | Sky Bet Championship |
| 18 | Tue 26 Nov | 21-6 v Norwich CityNorwich City 6-1 Plymouth Argyle | Sky Bet Championship |
| 19 | Sat 30 Nov | 20-4 v Bristol CityBristol City 4-0 Plymouth Argyle | Sky Bet Championship |
| 20 | Tue 10 Dec | 21-2 v Swansea CityPlymouth Argyle 1-2 Swansea City | Sky Bet Championship |
| 21 | Sat 14 Dec | 20-2 v Sheffield UnitedSheffield United 2-0 Plymouth Argyle | Sky Bet Championship |
| 22 | Sat 21 Dec | 23-3 v MiddlesbroughPlymouth Argyle 3-3 Middlesbrough | Sky Bet Championship |
| 23 | Thu 26 Dec | 20-4 v Coventry CityCoventry City 4-0 Plymouth Argyle | Sky Bet Championship |
| 24 | Sun 29 Dec | 20-2 v Oxford UnitedOxford United 2-0 Plymouth Argyle | Sky Bet Championship |
| 25 | Wed 1 Jan | 22-2 v Bristol CityPlymouth Argyle 2-2 Bristol City | Sky Bet Championship |
| 26 | Sat 4 Jan | 20-0 v Stoke CityStoke City 0-0 Plymouth Argyle | Sky Bet Championship |
| 27 | Sat 11 Jan | 21-0 v BrentfordBrentford 0-1 Plymouth Argyle | Emirates FA Cup Third Round |
| 28 | Tue 14 Jan | 21-1 v Oxford UnitedPlymouth Argyle 1-1 Oxford United | Sky Bet Championship |
| 29 | Sat 18 Jan | 20-1 v Queens Park RangersPlymouth Argyle 0-1 Queens Park Rangers | Sky Bet Championship |
| 30 | Wed 22 Jan | 20-5 v BurnleyPlymouth Argyle 0-5 Burnley | Sky Bet Championship |
| 31 | Sat 25 Jan | 22-2 v SunderlandSunderland 2-2 Plymouth Argyle | Sky Bet Championship |
| 32 | Wed 12 Feb | 25-1 v MillwallPlymouth Argyle 5-1 Millwall | Sky Bet Championship |
| 33 | Sat 22 Feb | 21-1 v Cardiff CityPlymouth Argyle 1-1 Cardiff City | Sky Bet Championship |
| 34 | Sat 1 Mar | 21-3 v Manchester CityManchester City 3-1 Plymouth Argyle | Emirates FA Cup Fifth Round |
| 35 | Tue 4 Mar | 20-2 v Hull CityHull City 2-0 Plymouth Argyle | Sky Bet Championship |
| 36 | Sat 8 Mar | 20-3 v Sheffield WednesdayPlymouth Argyle 0-3 Sheffield Wednesday | Sky Bet Championship |
| 37 | Wed 12 Mar | 22-1 v PortsmouthPortsmouth 1-2 Plymouth Argyle | Sky Bet Championship |
| 38 | Sat 15 Mar | 22-3 v Derby CountyPlymouth Argyle 2-3 Derby County | Sky Bet Championship |
| 39 | Sat 29 Mar | 20-0 v WatfordWatford 0-0 Plymouth Argyle | Sky Bet Championship |
| 40 | Sat 5 Apr | 22-1 v Norwich CityPlymouth Argyle 2-1 Norwich City | Sky Bet Championship |
| 41 | Wed 9 Apr | 20-3 v Swansea CitySwansea City 3-0 Plymouth Argyle | Sky Bet Championship |
| 42 | Sat 12 Apr | 22-1 v Sheffield UnitedPlymouth Argyle 2-1 Sheffield United | Sky Bet Championship |
| 43 | Fri 18 Apr | 21-2 v MiddlesbroughMiddlesbrough 2-1 Plymouth Argyle | Sky Bet Championship |
| 44 | Mon 21 Apr | 23-1 v Coventry CityPlymouth Argyle 3-1 Coventry City | Sky Bet Championship |
| 45 | Sat 26 Apr | 22-1 v Preston North EndPreston North End 1-2 Plymouth Argyle | Sky Bet Championship |
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