| 1 | Sat 5 Aug | 150-2 v Cambridge UnitedCambridge United 2-0 Oxford United | Sky Bet League One |
| 2 | Wed 9 Aug | 151-5 v Bristol CityBristol City 5-1 Oxford United | Carabao Cup First Round South |
| 3 | Tue 15 Aug | 152-1 v Derby CountyDerby County 1-2 Oxford United | Sky Bet League One |
| 4 | Sat 19 Aug | 153-1 v BarnsleyBarnsley 1-3 Oxford United | Sky Bet League One |
| 5 | Sat 26 Aug | 152-1 v Charlton AthleticOxford United 2-1 Charlton Athletic | Sky Bet League One |
| 6 | Sat 2 Sep | 15 1-2 v Port ValeOxford United 1-2 Port Vale | Sky Bet League One |
| 7 | Sat 16 Sep | 153-0 v Fleetwood TownFleetwood Town 0-3 Oxford United | Sky Bet League One |
| 8 | Tue 19 Sep | 150-1 v Milton Keynes DonsOxford United 0-1 Milton Keynes Dons | EFL Trophy |
| 9 | Sat 30 Sep | 153-1 v StevenageStevenage 1-3 Oxford United | Sky Bet League One |
| 10 | Tue 3 Oct | 153-0 v Shrewsbury TownOxford United 3-0 Shrewsbury Town | Sky Bet League One |
| 11 | Sat 7 Oct | 152-1 v Bristol RoversOxford United 2-1 Bristol Rovers | Sky Bet League One |
| 12 | Sat 21 Oct | 151-1 v BlackpoolOxford United 1-1 Blackpool | Sky Bet League One |
| 13 | Sat 28 Oct | 152-2 v Wycombe WanderersOxford United 2-2 Wycombe Wanderers | Sky Bet League One |
| 14 | Tue 31 Oct | 152-0 v Lincoln CityLincoln City 0-2 Oxford United | Sky Bet League One |
| 15 | Sat 11 Nov | 153-2 v Leyton OrientLeyton Orient 2-3 Oxford United | Sky Bet League One |
| 16 | Sat 25 Nov | 150-2 v Cheltenham TownCheltenham Town 2-0 Oxford United | Sky Bet League One |
| 17 | Tue 28 Nov | 150-0 v Bolton WanderersOxford United 0-0 Bolton Wanderers | Sky Bet League One |
| 18 | Sat 2 Dec | 152-0 v Grimsby TownOxford United 2-0 Grimsby Town | Emirates FA Cup Second Round |
| 19 | Tue 5 Dec | 151-0 v Forest Green RoversForest Green Rovers 0-1 Oxford United | EFL Trophy Second Round |
| 20 | Sat 9 Dec | 150-3 v Peterborough UnitedPeterborough United 3-0 Oxford United | Sky Bet League One |
| 21 | Tue 12 Dec | 151-1 v ReadingReading 1-1 Oxford United | Sky Bet League One |
| 22 | Sat 16 Dec | 153-0 v Burton AlbionOxford United 3-0 Burton Albion | Sky Bet League One |
| 23 | Sat 23 Dec | 151-2 v Northampton TownNorthampton Town 2-1 Oxford United | Sky Bet League One |
| 24 | Tue 26 Dec | 152-1 v Cambridge UnitedOxford United 2-1 Cambridge United | Sky Bet League One |
| 25 | Fri 29 Dec | 152-3 v Derby CountyOxford United 2-3 Derby County | Sky Bet League One |
| 26 | Mon 1 Jan | 152-1 v Charlton AthleticCharlton Athletic 1-2 Oxford United | Sky Bet League One |
| 27 | Sat 6 Jan | 152-6 v Coventry CityCoventry City 6-2 Oxford United | Emirates FA Cup Third Round |
| 28 | Tue 9 Jan | 150-2 v AFC WimbledonAFC Wimbledon 2-0 Oxford United | EFL Trophy Third Round |
| 29 | Sat 13 Jan | 153-1 v Carlisle UnitedCarlisle United 1-3 Oxford United | Sky Bet League One |
| 30 | Tue 23 Jan | 150-1 v BarnsleyOxford United 0-1 Barnsley | Sky Bet League One |
| 31 | Sat 27 Jan | 15 1-3 v Bristol RoversBristol Rovers 3-1 Oxford United | Sky Bet League One |
| 32 | Tue 30 Jan | 152-2 v PortsmouthOxford United 2-2 Portsmouth | Sky Bet League One |
| 33 | Sat 2 Mar | 151-2 v PortsmouthPortsmouth 2-1 Oxford United | Sky Bet League One |
| 34 | Sat 9 Mar | 152-1 v Cheltenham TownOxford United 2-1 Cheltenham Town | Sky Bet League One |
| 35 | Tue 12 Mar | 150-5 v Bolton WanderersBolton Wanderers 5-0 Oxford United | Sky Bet League One |
| 36 | Sat 6 Apr | 154-0 v Burton AlbionBurton Albion 0-4 Oxford United | Sky Bet League One |
| 37 | Sat 13 Apr | 155-0 v Peterborough UnitedOxford United 5-0 Peterborough United | Sky Bet League One |
| 38 | Tue 16 Apr | 150-1 v Lincoln CityOxford United 0-1 Lincoln City | Sky Bet League One |
| 39 | Fri 19 Apr | 151-1 v StevenageOxford United 1-1 Stevenage | Sky Bet League One |
| 40 | Sat 27 Apr | 15 2-1 v Exeter CityExeter City 1-2 Oxford United | Sky Bet League One |
| 41 | Sat 4 May | 151-0 v Peterborough UnitedOxford United 1-0 Peterborough United | Sky Bet League One Play-off Semi Final |
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