| 1 | Sun 8 Aug 2021 | 91-0 v Vitória GuimarãesVitória Guimarães 0-1 Portimonense |
| 2 | Sun 26 Sep 2021 | 9 0-0 v VizelaPortimonense 0-0 Vizela |
| 3 | Sun 3 Oct 2021 | 91-0 v BenficaBenfica 0-1 Portimonense |
| 4 | Sat 6 Nov 2021 | 92-0 v BelenensesPortimonense 2-0 Belenenses |
| 5 | Sat 27 Nov 2021 | 93-0 v FamalicãoFamalicão 0-3 Portimonense |
| 6 | Fri 3 Dec 2021 | 90-3 v FC PortoPortimonense 0-3 FC Porto |
| 7 | Sun 12 Dec 2021 | 91-0 v MoreirenseMoreirense 0-1 Portimonense |
| 8 | Sat 18 Dec 2021 | 91-1 v AroucaPortimonense 1-1 Arouca |
| 9 | Wed 29 Dec 2021 | 92-3 v Sporting LisbonSporting Lisbon 3-2 Portimonense |
| 10 | Sun 9 Jan 2022 | 91-2 v MarítimoPortimonense 1-2 Marítimo |
| 11 | Mon 17 Jan 2022 | 91-1 v Vitória GuimarãesPortimonense 1-1 Vitória Guimarães |
| 12 | Sun 23 Jan 2022 | 90-1 v Gil VicenteGil Vicente 1-0 Portimonense |
| 13 | Sun 30 Jan 2022 | 91-2 v TondelaPortimonense 1-2 Tondela |
| 14 | Sat 12 Feb 2022 | 91-1 v BoavistaPortimonense 1-1 Boavista |
| 15 | Mon 21 Feb 2022 | 91-1 v Santa ClaraSanta Clara 1-1 Portimonense |
| 16 | Sun 27 Feb 2022 | 9 1-1 v VizelaVizela 1-1 Portimonense |
| 17 | Sat 5 Mar 2022 | 91-2 v BenficaPortimonense 1-2 Benfica |
| 18 | Sat 12 Mar 2022 | 90-2 v Estoril PraiaEstoril Praia 2-0 Portimonense |
| 19 | Sun 20 Mar 2022 | 91-2 v Sporting BragaPortimonense 1-2 Sporting Braga |
| 20 | Sat 2 Apr 2022 | 90-2 v BelenensesBelenenses 2-0 Portimonense |
| 21 | Sun 10 Apr 2022 | 91-0 v FamalicãoPortimonense 1-0 Famalicão |
| 22 | Sat 16 Apr 2022 | 90-7 v FC PortoFC Porto 7-0 Portimonense |
| 23 | Sat 23 Apr 2022 | 91-0 v MoreirensePortimonense 1-0 Moreirense |
| 24 | Sat 30 Apr 2022 | 90-1 v AroucaArouca 1-0 Portimonense |
| 25 | Sat 7 May 2022 | 92-3 v Sporting LisbonPortimonense 2-3 Sporting Lisbon |
| 26 | Sat 14 May 2022 | 91-0 v MarítimoMarítimo 0-1 Portimonense |
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