| 1 | Sat 23 Sep | 41-0 v BurnleyBurnley 0-1 Manchester United |
| 2 | Sat 30 Sep | 4 0-1 v Crystal PalaceManchester United 0-1 Crystal Palace |
| 3 | Sat 7 Oct | 42-1 v BrentfordManchester United 2-1 Brentford |
| 4 | Sat 21 Oct | 42-1 v Sheffield UnitedSheffield United 1-2 Manchester United |
| 5 | Sun 29 Oct | 4 0-3 v Manchester CityManchester United 0-3 Manchester City |
| 6 | Sun 26 Nov | 43-0 v EvertonEverton 0-3 Manchester United |
| 7 | Sat 2 Dec | 40-1 v Newcastle UnitedNewcastle United 1-0 Manchester United |
| 8 | Wed 6 Dec | 42-1 v ChelseaManchester United 2-1 Chelsea |
| 9 | Sat 9 Dec | 40-3 v AFC BournemouthManchester United 0-3 AFC Bournemouth |
| 10 | Sun 17 Dec | 4 0-0 v LiverpoolLiverpool 0-0 Manchester United |
| 11 | Sun 11 Feb | 42-1 v Aston VillaAston Villa 1-2 Manchester United |
| 12 | Sun 18 Feb | 42-1 v Luton TownLuton Town 1-2 Manchester United |
| 13 | Sun 3 Mar | 41-3 v Manchester CityManchester City 3-1 Manchester United |
| 14 | Sat 9 Mar | 42-0 v EvertonManchester United 2-0 Everton |
| 15 | Sun 7 Apr | 42-2 v LiverpoolManchester United 2-2 Liverpool |
| 16 | Wed 24 Apr | 44-2 v Sheffield UnitedManchester United 4-2 Sheffield United |
| 17 | Sat 27 Apr | 41-1 v BurnleyManchester United 1-1 Burnley |
| 18 | Mon 6 May | 4 0-4 v Crystal PalaceCrystal Palace 4-0 Manchester United |
| 19 | Sun 12 May | 40-1 v ArsenalManchester United 0-1 Arsenal |
| 20 | Wed 15 May | 4 3-2 v Newcastle UnitedManchester United 3-2 Newcastle United |
| 21 | Sun 19 May | 4 2-0 v Brighton & Hove AlbionBrighton & Hove Albion 0-2 Manchester United |
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